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Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus.
Iannitelli AF, Hassenein L, Mulvey B, Blankenship HE, Liles LC, Sharpe AL, Pare JF, Segal A, Sloan SA, Martinowich K, McCann KE, Dougherty JD, Smith Y, Beckstead MJ, Weinshenker D. Iannitelli AF, et al. bioRxiv [Preprint]. 2024 Aug 4:2023.03.07.530845. doi: 10.1101/2023.03.07.530845. bioRxiv. 2024. PMID: 36945637 Free PMC article. Preprint.
The Neurotoxin DSP-4 Dysregulates the Locus Coeruleus-Norepinephrine System and Recapitulates Molecular and Behavioral Aspects of Prodromal Neurodegenerative Disease.
Iannitelli AF, Kelberman MA, Lustberg DJ, Korukonda A, McCann KE, Mulvey B, Segal A, Liles LC, Sloan SA, Dougherty JD, Weinshenker D. Iannitelli AF, et al. eNeuro. 2023 Jan 6;10(1):ENEURO.0483-22.2022. doi: 10.1523/ENEURO.0483-22.2022. Print 2023 Jan. eNeuro. 2023. PMID: 36635251 Free PMC article.
Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease.
Butkovich LM, Houser MC, Chalermpalanupap T, Porter-Stransky KA, Iannitelli AF, Boles JS, Lloyd GM, Coomes AS, Eidson LN, De Sousa Rodrigues ME, Oliver DL, Kelly SD, Chang J, Bengoa-Vergniory N, Wade-Martins R, Giasson BI, Joers V, Weinshenker D, Tansey MG. Butkovich LM, et al. Among authors: iannitelli af. J Neurosci. 2020 Sep 23;40(39):7559-7576. doi: 10.1523/JNEUROSCI.1468-19.2020. Epub 2020 Aug 31. J Neurosci. 2020. PMID: 32868457 Free PMC article.