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Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus.
Iannitelli AF, Hassanein L, Tish MM, Mulvey B, Blankenship HE, Korukonda A, Liles LC, Sharpe AL, Pare JF, Villalba R, Segal A, Sloan SA, Martinowich K, Dougherty JD, McCann KE, Smith Y, Beckstead MJ, Weinshenker D. Iannitelli AF, et al. bioRxiv [Preprint]. 2025 Apr 5:2023.03.07.530845. doi: 10.1101/2023.03.07.530845. bioRxiv. 2025. PMID: 36945637 Free PMC article. Preprint.
Transgenic Mice Expressing Human α-Synuclein in Noradrenergic Neurons Develop Locus Ceruleus Pathology and Nonmotor Features of Parkinson's Disease.
Butkovich LM, Houser MC, Chalermpalanupap T, Porter-Stransky KA, Iannitelli AF, Boles JS, Lloyd GM, Coomes AS, Eidson LN, De Sousa Rodrigues ME, Oliver DL, Kelly SD, Chang J, Bengoa-Vergniory N, Wade-Martins R, Giasson BI, Joers V, Weinshenker D, Tansey MG. Butkovich LM, et al. Among authors: iannitelli af. J Neurosci. 2020 Sep 23;40(39):7559-7576. doi: 10.1523/JNEUROSCI.1468-19.2020. Epub 2020 Aug 31. J Neurosci. 2020. PMID: 32868457 Free PMC article.