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Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates.

Savastano A, Ibáñez de Opakua A, Rankovic M, Zweckstetter M. Savastano A, et al. Among authors: ibanez de opakua a. Nat Commun. 2020 Nov 27;11(1):6041. doi: 10.1038/s41467-020-19843-1. Nat Commun. 2020. PMID: 33247108 Free PMC article.

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A Novel SNCA A30G Mutation Causes Familial Parkinson's Disease.

Liu H, Koros C, Strohäker T, Schulte C, Bozi M, Varvaresos S, Ibáñez de Opakua A, Simitsi AM, Bougea A, Voumvourakis K, Maniati M, Papageorgiou SG, Hauser AK, Becker S, Zweckstetter M, Stefanis L, Gasser T. Liu H, et al. Among authors: ibanez de opakua a. Mov Disord. 2021 Jul;36(7):1624-1633. doi: 10.1002/mds.28534. Epub 2021 Feb 22. Mov Disord. 2021. PMID: 33617693

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Determination of Complex Small-Molecule Structures Using Molecular Alignment Simulation.

Ibáñez de Opakua A, Klama F, Ndukwe IE, Martin GE, Williamson RT, Zweckstetter M. Ibáñez de Opakua A, et al. Angew Chem Int Ed Engl. 2020 Apr 6;59(15):6172-6176. doi: 10.1002/anie.202000311. Epub 2020 Feb 24. Angew Chem Int Ed Engl. 2020. PMID: 31971323 Free PMC article.

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Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution.

Ukmar-Godec T, Fang P, Ibáñez de Opakua A, Henneberg F, Godec A, Pan KT, Cima-Omori MS, Chari A, Mandelkow E, Urlaub H, Zweckstetter M. Ukmar-Godec T, et al. Among authors: ibanez de opakua a. Sci Adv. 2020 Jul 22;6(30):eaba3916. doi: 10.1126/sciadv.aba3916. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832664 Free PMC article.

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Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization.

Dominguez-Meijide A, Vasili E, König A, Cima-Omori MS, Ibáñez de Opakua A, Leonov A, Ryazanov S, Zweckstetter M, Griesinger C, Outeiro TF. Dominguez-Meijide A, et al. Among authors: ibanez de opakua a. Sci Rep. 2020 Jul 30;10(1):12827. doi: 10.1038/s41598-020-69744-y. Sci Rep. 2020. PMID: 32732936 Free PMC article.

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TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.

Hoffmann S, Smedegaard S, Nakamura K, Mortuza GB, Räschle M, Ibañez de Opakua A, Oka Y, Feng Y, Blanco FJ, Mann M, Montoya G, Groth A, Bekker-Jensen S, Mailand N. Hoffmann S, et al. Among authors: ibanez de opakua a. J Cell Biol. 2016 Jan 4;212(1):63-75. doi: 10.1083/jcb.201506071. Epub 2015 Dec 28. J Cell Biol. 2016. PMID: 26711499 Free PMC article.

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Molecular Basis of Small-Molecule Binding to α-Synuclein.

Robustelli P, Ibanez-de-Opakua A, Campbell-Bezat C, Giordanetto F, Becker S, Zweckstetter M, Pan AC, Shaw DE. Robustelli P, et al. Among authors: ibanez de opakua a. J Am Chem Soc. 2022 Feb 16;144(6):2501-2510. doi: 10.1021/jacs.1c07591. Epub 2022 Feb 7. J Am Chem Soc. 2022. PMID: 35130691 Free PMC article.

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A generalized approach for NMR studies of lipid-protein interactions based on sparse fluorination of acyl chains.

De Biasio A , Ibáñez de Opakua A , Bostock MJ , Nietlispach D , Diercks T , Blanco FJ . De Biasio A , et al. Among authors: ibanez de opakua a. Chem Commun (Camb). 2018 Jun 28;54(53):7306-7309. doi: 10.1039/c8cc02483a. Chem Commun (Camb). 2018. PMID: 29905339

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The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark.

Ormaza G, Rodríguez JA, Ibáñez de Opakua A, Merino N, Villate M, Gorroño I, Rábano M, Palmero I, Vilaseca M, Kypta R, Vivanco MDM, Rojas AL, Blanco FJ. Ormaza G, et al. Among authors: ibanez de opakua a. J Mol Biol. 2019 May 31;431(12):2298-2319. doi: 10.1016/j.jmb.2019.04.018. Epub 2019 Apr 24. J Mol Biol. 2019. PMID: 31026448 Free article.

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The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).

Gonzalez-Magaña A, Ibáñez de Opakua A, Romano-Moreno M, Murciano-Calles J, Merino N, Luque I, Rojas AL, Onesti S, Blanco FJ, De Biasio A. Gonzalez-Magaña A, et al. Among authors: ibanez de opakua a. J Biol Chem. 2019 Mar 15;294(11):3947-3956. doi: 10.1074/jbc.RA118.006391. Epub 2019 Jan 17. J Biol Chem. 2019. PMID: 30655288 Free PMC article.

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