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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 12
2003 15
2004 13
2005 26
2006 20
2007 24
2008 30
2009 29
2010 32
2011 34
2012 60
2013 63
2014 52
2015 32
2016 24
2017 39
2018 34
2019 33
2020 36
2021 54
2022 53
2023 30
2024 30

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645 results

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Page 1
Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial.
Davies M, Færch L, Jeppesen OK, Pakseresht A, Pedersen SD, Perreault L, Rosenstock J, Shimomura I, Viljoen A, Wadden TA, Lingvay I; STEP 2 Study Group. Davies M, et al. Among authors: shimomura i. Lancet. 2021 Mar 13;397(10278):971-984. doi: 10.1016/S0140-6736(21)00213-0. Epub 2021 Mar 2. Lancet. 2021. PMID: 33667417 Clinical Trial.
HSP47 levels determine the degree of body adiposity.
Shin J, Toyoda S, Okuno Y, Hayashi R, Nishitani S, Onodera T, Sakamoto H, Ito S, Kobayashi S, Nagao H, Kita S, Otsuki M, Fukuhara A, Nagata K, Shimomura I. Shin J, et al. Among authors: shimomura i. Nat Commun. 2023 Nov 11;14(1):7319. doi: 10.1038/s41467-023-43080-x. Nat Commun. 2023. PMID: 37951979 Free PMC article.
Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice.
Nakamura Y, Kita S, Tanaka Y, Fukuda S, Obata Y, Okita T, Nishida H, Takahashi Y, Kawachi Y, Tsugawa-Shimizu Y, Fujishima Y, Nishizawa H, Takakura Y, Miyagawa S, Sawa Y, Maeda N, Shimomura I. Nakamura Y, et al. Among authors: shimomura i. Mol Ther. 2020 Oct 7;28(10):2203-2219. doi: 10.1016/j.ymthe.2020.06.026. Epub 2020 Jul 10. Mol Ther. 2020. PMID: 32652045 Free PMC article.
Suppression of aging in mice by the hormone Klotho.
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M. Kurosu H, et al. Among authors: shimomura i. Science. 2005 Sep 16;309(5742):1829-33. doi: 10.1126/science.1112766. Epub 2005 Aug 25. Science. 2005. PMID: 16123266 Free PMC article.
The Rubicon-WIPI axis regulates exosome biogenesis during ageing.
Yanagawa K, Kuma A, Hamasaki M, Kita S, Yamamuro T, Nishino K, Nakamura S, Omori H, Kaminishi T, Oikawa S, Kato Y, Edahiro R, Kawagoe R, Taniguchi T, Tanaka Y, Shima T, Tabata K, Iwatani M, Bekku N, Hanayama R, Okada Y, Akimoto T, Kosako H, Takahashi A, Shimomura I, Sakata Y, Yoshimori T. Yanagawa K, et al. Among authors: shimomura i. Nat Cell Biol. 2024 Sep;26(9):1558-1570. doi: 10.1038/s41556-024-01481-0. Epub 2024 Aug 22. Nat Cell Biol. 2024. PMID: 39174742
Human adipose-derived mesenchymal stem cells prevent type 1 diabetes induced by immune checkpoint blockade.
Kawada-Horitani E, Kita S, Okita T, Nakamura Y, Nishida H, Honma Y, Fukuda S, Tsugawa-Shimizu Y, Kozawa J, Sakaue T, Kawachi Y, Fujishima Y, Nishizawa H, Azuma M, Maeda N, Shimomura I. Kawada-Horitani E, et al. Among authors: shimomura i. Diabetologia. 2022 Jul;65(7):1185-1197. doi: 10.1007/s00125-022-05708-3. Epub 2022 May 5. Diabetologia. 2022. PMID: 35511238 Free PMC article.
Increased oxidative stress in obesity and its impact on metabolic syndrome.
Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I. Furukawa S, et al. Among authors: shimomura i. J Clin Invest. 2004 Dec;114(12):1752-61. doi: 10.1172/JCI21625. J Clin Invest. 2004. PMID: 15599400 Free PMC article.
Retraction.
Fukuhara A, Matsuda M, Nishizawa M, Segawa K, Tanaka M, Kishimoto K, Matsuki Y, Murakami M, Ichisaka T, Murakami H, Watanabe E, Takagi T, Akiyoshi M, Ohtsubo T, Kihara S, Yamashita S, Makishima M, Funahashi T, Yamanaka S, Hiramatsu R, Matsuzawa Y, Shimomura I. Fukuhara A, et al. Among authors: shimomura i. Science. 2007 Oct 26;318(5850):565. doi: 10.1126/science.318.5850.565b. Science. 2007. PMID: 17962537 No abstract available.
Definition, criteria, and core concepts of guidelines for the management of obesity disease in Japan.
Ogawa W, Hirota Y, Miyazaki S, Nakamura T, Ogawa Y, Shimomura I, Yamauchi T, Yokote K; Creation Committee for Guidelines for the Management of Obesity Disease 2022 by Japan Society for the Study of Obesity (JASSO). Ogawa W, et al. Among authors: shimomura i. Endocr J. 2024 Mar 28;71(3):223-231. doi: 10.1507/endocrj.EJ23-0593. Epub 2023 Dec 20. Endocr J. 2024. PMID: 38123337 Free article.
645 results