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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 2
1953 1
1956 1
1981 1
1998 1
2000 2
2001 2
2002 4
2003 2
2004 5
2005 4
2006 4
2007 4
2008 8
2009 6
2010 7
2011 19
2012 9
2013 17
2014 9
2015 19
2016 20
2017 24
2018 18
2019 22
2020 25
2021 36
2022 27
2023 14

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282 results

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Page 1
The future of engineered immune cell therapies.
Irvine DJ, Maus MV, Mooney DJ, Wong WW. Irvine DJ, et al. Science. 2022 Nov 25;378(6622):853-858. doi: 10.1126/science.abq6990. Epub 2022 Nov 24. Science. 2022. PMID: 36423279 Free PMC article. Review.
Enhancing cancer immunotherapy with nanomedicine.
Irvine DJ, Dane EL. Irvine DJ, et al. Nat Rev Immunol. 2020 May;20(5):321-334. doi: 10.1038/s41577-019-0269-6. Epub 2020 Jan 31. Nat Rev Immunol. 2020. PMID: 32005979 Free PMC article. Review.
STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity.
Dane EL, Belessiotis-Richards A, Backlund C, Wang J, Hidaka K, Milling LE, Bhagchandani S, Melo MB, Wu S, Li N, Donahue N, Ni K, Ma L, Okaniwa M, Stevens MM, Alexander-Katz A, Irvine DJ. Dane EL, et al. Among authors: irvine dj. Nat Mater. 2022 Jun;21(6):710-720. doi: 10.1038/s41563-022-01251-z. Epub 2022 May 23. Nat Mater. 2022. PMID: 35606429 Free PMC article.
Long-primed germinal centres with enduring affinity maturation and clonal migration.
Lee JH, Sutton HJ, Cottrell CA, Phung I, Ozorowski G, Sewall LM, Nedellec R, Nakao C, Silva M, Richey ST, Torres JL, Lee WH, Georgeson E, Kubitz M, Hodges S, Mullen TM, Adachi Y, Cirelli KM, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Kalyuzhniy O, Liguori A, Carnathan DG, Silvestri G, Shen X, Montefiori DC, Veazey RS, Ward AB, Hangartner L, Burton DR, Irvine DJ, Schief WR, Crotty S. Lee JH, et al. Among authors: irvine dj. Nature. 2022 Sep;609(7929):998-1004. doi: 10.1038/s41586-022-05216-9. Epub 2022 Sep 21. Nature. 2022. PMID: 36131022 Free PMC article.
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Borriello F, Poli V, Shrock E, Spreafico R, Liu X, Pishesha N, Carpenet C, Chou J, Di Gioia M, McGrath ME, Dillen CA, Barrett NA, Lacanfora L, Franco ME, Marongiu L, Iwakura Y, Pucci F, Kruppa MD, Ma Z, Lowman DW, Ensley HE, Nanishi E, Saito Y, O'Meara TR, Seo HS, Dhe-Paganon S, Dowling DJ, Frieman M, Elledge SJ, Levy O, Irvine DJ, Ploegh HL, Williams DL, Zanoni I. Borriello F, et al. Among authors: irvine dj. Cell. 2022 Feb 17;185(4):614-629.e21. doi: 10.1016/j.cell.2022.01.009. Epub 2022 Feb 10. Cell. 2022. PMID: 35148840 Free PMC article.
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.
Silva M, Kato Y, Melo MB, Phung I, Freeman BL, Li Z, Roh K, Van Wijnbergen JW, Watkins H, Enemuo CA, Hartwell BL, Chang JYH, Xiao S, Rodrigues KA, Cirelli KM, Li N, Haupt S, Aung A, Cossette B, Abraham W, Kataria S, Bastidas R, Bhiman J, Linde C, Bloom NI, Groschel B, Georgeson E, Phelps N, Thomas A, Bals J, Carnathan DG, Lingwood D, Burton DR, Alter G, Padera TP, Belcher AM, Schief WR, Silvestri G, Ruprecht RM, Crotty S, Irvine DJ. Silva M, et al. Among authors: irvine dj. Sci Immunol. 2021 Dec 3;6(66):eabf1152. doi: 10.1126/sciimmunol.abf1152. Epub 2021 Dec 3. Sci Immunol. 2021. PMID: 34860581 Free PMC article.
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Metallo CM, Gameiro PA, Bell EL, Mattaini KR, Yang J, Hiller K, Jewell CM, Johnson ZR, Irvine DJ, Guarente L, Kelleher JK, Vander Heiden MG, Iliopoulos O, Stephanopoulos G. Metallo CM, et al. Among authors: irvine dj. Nature. 2011 Nov 20;481(7381):380-4. doi: 10.1038/nature10602. Nature. 2011. PMID: 22101433 Free PMC article.
Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer.
Westcott PMK, Sacks NJ, Schenkel JM, Ely ZA, Smith O, Hauck H, Jaeger AM, Zhang D, Backlund CM, Beytagh MC, Patten JJ, Elbashir R, Eng G, Irvine DJ, Yilmaz OH, Jacks T. Westcott PMK, et al. Among authors: irvine dj. Nat Cancer. 2021 Oct;2(10):1071-1085. doi: 10.1038/s43018-021-00247-z. Epub 2021 Sep 30. Nat Cancer. 2021. PMID: 34738089 Free PMC article.
282 results