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1852 2
1856 3
1864 2
1865 3
1866 1
1867 1
1868 1
1870 1
1871 1
1872 4
1874 1
1875 1
1876 2
1878 3
1879 1
1881 3
1885 1
1886 4
1887 2
1889 1
1890 2
1891 1
1895 2
1896 1
1898 6
1899 1
1901 2
1902 2
1904 1
1905 4
1907 1
1908 2
1909 2
1910 4
1912 1
1913 2
1914 1
1915 2
1917 1
1918 1
1921 10
1924 4
1926 1
1927 1
1929 4
1930 3
1931 2
1932 1
1933 4
1934 2
1935 2
1936 2
1937 1
1938 4
1939 2
1940 1
1942 4
1944 1
1945 13
1946 28
1947 44
1948 56
1949 56
1950 68
1951 81
1952 80
1953 75
1954 82
1955 100
1956 59
1957 66
1958 60
1959 63
1960 38
1961 72
1962 81
1963 140
1964 135
1965 91
1966 104
1967 121
1968 133
1969 135
1970 139
1971 181
1972 143
1973 181
1974 179
1975 175
1976 125
1977 141
1978 143
1979 161
1980 160
1981 182
1982 188
1983 190
1984 212
1985 213
1986 210
1987 231
1988 244
1989 301
1990 313
1991 313
1992 321
1993 330
1994 333
1995 367
1996 372
1997 375
1998 389
1999 419
2000 479
2001 509
2002 496
2003 564
2004 606
2005 588
2006 735
2007 654
2008 774
2009 819
2010 823
2011 888
2012 984
2013 1075
2014 1177
2015 1210
2016 1272
2017 1347
2018 1456
2019 1530
2020 1796
2021 1966
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Page 1
Itch: Pathogenesis and treatment.
Sutaria N, Adawi W, Goldberg R, Roh YS, Choi J, Kwatra SG. Sutaria N, et al. J Am Acad Dermatol. 2022 Jan;86(1):17-34. doi: 10.1016/j.jaad.2021.07.078. Epub 2021 Oct 12. J Am Acad Dermatol. 2022. PMID: 34648873 Review.
Optimal management of itch requires that treatment approaches be tailored to specific etiologic itch subtypes. ...In the second article of this 2-part series, we outline our current understanding of itch pathogenesis and discuss available and emerging treatme …
Optimal management of itch requires that treatment approaches be tailored to specific etiologic itch subtypes. ...In the secon …
Physiology and Pathophysiology of Itch.
Cevikbas F, Lerner EA. Cevikbas F, et al. Physiol Rev. 2020 Jul 1;100(3):945-982. doi: 10.1152/physrev.00017.2019. Epub 2019 Dec 23. Physiol Rev. 2020. PMID: 31869278 Free PMC article. Review.
Itch is a topic to which everyone can relate. The physiological roles of itch are increasingly understood and appreciated. ...Itch is a disease, not only a symptom of disease....
Itch is a topic to which everyone can relate. The physiological roles of itch are increasingly understood and appreciated. ... …
Itch.
Murphy LN, Lumpkin EA, Bautista DM. Murphy LN, et al. Curr Biol. 2025 Jan 20;35(2):R51-R57. doi: 10.1016/j.cub.2024.12.021. Curr Biol. 2025. PMID: 39837268 Free article. Review.
Whether due to an insect bite, a poisonous plant, or a chronic skin disease, everyone has experienced the urgent sensation of itch and the sweet relief of scratching. The itch-scratch cycle is so powerful that just reading about itch or seeing someone scratch …
Whether due to an insect bite, a poisonous plant, or a chronic skin disease, everyone has experienced the urgent sensation of itch an …
Peripheral itch sensitization in atopic dermatitis.
Tominaga M, Takamori K. Tominaga M, et al. Allergol Int. 2022 Jul;71(3):265-277. doi: 10.1016/j.alit.2022.04.003. Epub 2022 May 25. Allergol Int. 2022. PMID: 35624035 Free article. Review.
Atopic dermatitis is a skin disorder caused by skin dryness and barrier dysfunction, resulting in skin inflammation and chronic itch (or pruritus). The pathogenesis of atopic dermatitis is thought to be initiated by a lowering of the itch threshold due to dry …
Atopic dermatitis is a skin disorder caused by skin dryness and barrier dysfunction, resulting in skin inflammation and chronic itch …
Itch: Epidemiology, clinical presentation, and diagnostic workup.
Roh YS, Choi J, Sutaria N, Kwatra SG. Roh YS, et al. J Am Acad Dermatol. 2022 Jan;86(1):1-14. doi: 10.1016/j.jaad.2021.07.076. Epub 2021 Aug 21. J Am Acad Dermatol. 2022. PMID: 34428534 Free PMC article. Review.
Itch, or pruritus, is the uncomfortable sensation underlying the desire to scratch. Itch is a very common complaint in the general population that can result from dermatologic, systemic (eg, renal, hepatobiliary, endocrine), paraneoplastic, neuropathic, and p …
Itch, or pruritus, is the uncomfortable sensation underlying the desire to scratch. Itch is a very common complaint in …
Itch: From mechanism to (novel) therapeutic approaches.
Yosipovitch G, Rosen JD, Hashimoto T. Yosipovitch G, et al. J Allergy Clin Immunol. 2018 Nov;142(5):1375-1390. doi: 10.1016/j.jaci.2018.09.005. J Allergy Clin Immunol. 2018. PMID: 30409247 Review.
In patients with these conditions, itch is often severe and significantly affects quality of life. Itch is encoded by 2 major neuronal pathways: histaminergic (in acute itch) and nonhistaminergic (in chronic itch). In the majority of cases, crosstalk e …
In patients with these conditions, itch is often severe and significantly affects quality of life. Itch is encoded by 2 major …
Peripheral and Central Mechanisms of Itch.
Dong X, Dong X. Dong X, et al. Neuron. 2018 May 2;98(3):482-494. doi: 10.1016/j.neuron.2018.03.023. Neuron. 2018. PMID: 29723501 Free PMC article. Review.
Itch interacts with the other sensory modalities at multiple locations, from its initiation in a particular dermatome to its transmission to the brain where it is finally perceived. In this review, we summarize the current understanding of the molecular and neural mechanis …
Itch interacts with the other sensory modalities at multiple locations, from its initiation in a particular dermatome to its transmis …
Neuropathic itch.
Steinhoff M, Oaklander AL, Szabó IL, Ständer S, Schmelz M. Steinhoff M, et al. Pain. 2019 May;160 Suppl 1:S11-S16. doi: 10.1097/j.pain.0000000000001551. Pain. 2019. PMID: 31008844 Review.
In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their exact role in the pathophysiology of neuropathic itch is still unclear. ...Thus, clinical neuropathy may generate itch by changes in the spatial an …
In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their exact role in the pat …
Atopic Dermatitis Itch: Scratching for an Explanation.
Biazus Soares G, Hashimoto T, Yosipovitch G. Biazus Soares G, et al. J Invest Dermatol. 2024 May;144(5):978-988. doi: 10.1016/j.jid.2023.10.048. Epub 2024 Feb 16. J Invest Dermatol. 2024. PMID: 38363270 Free article. Review.
Chronic pruritus is a cardinal symptom of atopic dermatitis (AD). The mechanisms underlying atopic itch involve intricate crosstalk among skin, immune components, and neural components. In this review, we explore these mechanisms, focusing on key players and interac …
Chronic pruritus is a cardinal symptom of atopic dermatitis (AD). The mechanisms underlying atopic itch involve intricate cros …
Basic mechanisms of itch.
Misery L, Pierre O, Le Gall-Ianotto C, Lebonvallet N, Chernyshov PV, Le Garrec R, Talagas M. Misery L, et al. J Allergy Clin Immunol. 2023 Jul;152(1):11-23. doi: 10.1016/j.jaci.2023.05.004. Epub 2023 May 16. J Allergy Clin Immunol. 2023. PMID: 37201903 Review.
Pruritus (or itch) is an unpleasant sensation leading to a desire to scratch. In the epidermis, there are selective C or Adelta epidermal nerve endings that are pruriceptors. ...A notable phenomenon is the sensitization to pruritus, in which regardless of the …
Pruritus (or itch) is an unpleasant sensation leading to a desire to scratch. In the epidermis, there are selective C or Adelt …
36,702 results
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