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Year Number of Results
2002 1
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278 results

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Page 1
ITGA3 acts as a purity-independent biomarker of both immunotherapy and chemotherapy resistance in pancreatic cancer: bioinformatics and experimental analysis.
Zheng X, Du Y, Liu M, Wang C. Zheng X, et al. Funct Integr Genomics. 2023 Jun 4;23(2):196. doi: 10.1007/s10142-023-01122-z. Funct Integr Genomics. 2023. Retraction in: Funct Integr Genomics. 2024 May 11;24(3):86. doi: 10.1007/s10142-024-01373-4 PMID: 37270717 Free PMC article. Retracted.
After constructing a three-gene (TMEM80, EIF4EBP1, and ITGA3) purity-independent Cox regression model using machine learning, ITGA3 was identified as a critical integrin subunit gene in pancreatic cancer. ITGA3 is involved in the molecular transformation from …
After constructing a three-gene (TMEM80, EIF4EBP1, and ITGA3) purity-independent Cox regression model using machine learning, ITGA …
YY1/ITGA3 pathway may affect trophoblastic cells migration and invasion ability.
Wang Y, Yang D, Zhu R, Dai F, Yuan M, Zhang L, Zheng Y, Liu S, Yang X, Cheng Y. Wang Y, et al. J Reprod Immunol. 2022 Sep;153:103666. doi: 10.1016/j.jri.2022.103666. Epub 2022 Jul 26. J Reprod Immunol. 2022. PMID: 35970081
Chip-seq dataset analysis results predict YY1 can regulate ITGA3/7 expression by binding to the promoter region of ITGA3/7. Furthermore, results from chip experiment, RT-PCR, Dual-luciferase reporter gene assay showed that YY1 was able to bind to the promoter region …
Chip-seq dataset analysis results predict YY1 can regulate ITGA3/7 expression by binding to the promoter region of ITGA3/7. Fu …
Evaluation of ITGA3 as a Biomarker of Progression and Recurrence in Papillary Thyroid Carcinoma.
Zhang G, Li B, Lin Y. Zhang G, et al. Front Oncol. 2022 Jan 31;11:614955. doi: 10.3389/fonc.2021.614955. eCollection 2021. Front Oncol. 2022. PMID: 35174063 Free PMC article.

Survival analysis showed that patients with high expression of ITGA3 in PTC had a poorer relapse-free survival (RFS) than patients with low expression of ITGA3 (P < 0.05). ...High expression of ITGA3 may have the potential role of predicting PTC recurrence

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Survival analysis showed that patients with high expression of ITGA3 in PTC had a poorer relapse-free survival (RFS) than patients wi …
ITGA3 serves as a diagnostic and prognostic biomarker for pancreatic cancer.
Jiao Y, Li Y, Liu S, Chen Q, Liu Y. Jiao Y, et al. Onco Targets Ther. 2019 May 27;12:4141-4152. doi: 10.2147/OTT.S201675. eCollection 2019. Onco Targets Ther. 2019. PMID: 31213833 Free PMC article.
Survival analysis and Cox regression analysis were used to examine the prognostic value of ITGA3 expression. Gene Set Enrichment Analysis (GSEA) was used to identify signaling pathways related to ITGA3 expression. ...Cox analysis indicated that high ITGA3 exp …
Survival analysis and Cox regression analysis were used to examine the prognostic value of ITGA3 expression. Gene Set Enrichment Anal …
ITGA3 Is Associated With Immune Cell Infiltration and Serves as a Favorable Prognostic Biomarker for Breast Cancer.
Li Y, Li F, Bai X, Li Y, Ni C, Zhao X, Zhang D. Li Y, et al. Front Oncol. 2021 May 20;11:658547. doi: 10.3389/fonc.2021.658547. eCollection 2021. Front Oncol. 2021. PMID: 34094951 Free PMC article.
High expression of ITGA3 was associated with better prognosis of breast cancer patients. ROC analysis indicated that ITGA3 had significant diagnostic value. Genomic analysis revealed that promoter methylation of ITGA3 leads to transcriptional silencing, which …
High expression of ITGA3 was associated with better prognosis of breast cancer patients. ROC analysis indicated that ITGA3 had …
ITGA3 interacts with VASP to regulate stemness and epithelial-mesenchymal transition of breast cancer cells.
Zhang H, Cui X, Cao A, Li X, Li L. Zhang H, et al. Gene. 2020 Apr 15;734:144396. doi: 10.1016/j.gene.2020.144396. Epub 2020 Jan 25. Gene. 2020. PMID: 31987909
However, the mechanism of ITGA3 in breast cancer is unknown. METHODS: The impact of ITGA3 on the biological features of breast cancer cells was explored using the Transwell and wound healing assays. ...Our findings indicate that ITGA3 interacts with VASP and …
However, the mechanism of ITGA3 in breast cancer is unknown. METHODS: The impact of ITGA3 on the biological features of breast …
Detection of bladder cancer with aberrantly fucosylated ITGA3.
Islam MK, Syed P, Dhondt B, Gidwani K, Pettersson K, Lamminmäki U, Leivo J. Islam MK, et al. Anal Biochem. 2021 Sep 1;628:114283. doi: 10.1016/j.ab.2021.114283. Epub 2021 Jun 5. Anal Biochem. 2021. PMID: 34102169 Free article.
We describe a simple, non-invasive assay to identify fucosylated-glycoisoform of integrin alpha-3 (ITGA3) directly from unprocessed urine. ITGA3 was detected directly from the urine of bladder cancer (BlCa) (n = 13) and benign prostatic hyperplasia (BPH) (n = 9) pat …
We describe a simple, non-invasive assay to identify fucosylated-glycoisoform of integrin alpha-3 (ITGA3) directly from unprocessed u …
Zinc-Dependent Regulation of ZEB1 and YAP1 Coactivation Promotes Epithelial-Mesenchymal Transition Plasticity and Metastasis in Pancreatic Cancer.
Liu M, Zhang Y, Yang J, Zhan H, Zhou Z, Jiang Y, Shi X, Fan X, Zhang J, Luo W, Fung KA, Xu C, Bronze MS, Houchen CW, Li M. Liu M, et al. Gastroenterology. 2021 Apr;160(5):1771-1783.e1. doi: 10.1053/j.gastro.2020.12.077. Epub 2021 Jan 6. Gastroenterology. 2021. PMID: 33421513 Free PMC article.
The transcriptional regulation of ZEB1, YAP1, and ITGA3 by ZIP4 was determined by chromatin immunoprecipitation, co-immunoprecipitation, and luciferase reporter assays. ...The ZIP4-miR-373-LATS2-ZEB1/YAP1-ITGA3 signaling axis has a significant impact on pancreatic c …
The transcriptional regulation of ZEB1, YAP1, and ITGA3 by ZIP4 was determined by chromatin immunoprecipitation, co-immunoprecipitati …
Varying mechanical forces drive sensory epithelium formation.
Xia M, Wu M, Li Y, Liu Y, Jia G, Lou Y, Ma J, Gao Q, Xie M, Chen Y, He Y, Li H, Li W. Xia M, et al. Sci Adv. 2023 Nov 3;9(44):eadf2664. doi: 10.1126/sciadv.adf2664. Epub 2023 Nov 3. Sci Adv. 2023. PMID: 37922362 Free PMC article.
As the driving force, moderate ECM stiffness activated the expansion of cochlear progenitor cell (CPC)-derived epithelial organoids by modulating the integrin alpha3 (ITGA3)/F-actin cytoskeleton/YAP signaling. Higher stiffness induced the transition of CPCs into sensory ha …
As the driving force, moderate ECM stiffness activated the expansion of cochlear progenitor cell (CPC)-derived epithelial organoids by modul …
278 results