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Year Number of Results
1977 1
1983 2
1986 1
2003 1
2012 1
2013 1
2017 1
2018 2
2019 2
2020 9
2021 4
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22 results
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Page 1
Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening.
Lin GL, Wilson KM, Ceribelli M, Stanton BZ, Woo PJ, Kreimer S, Qin EY, Zhang X, Lennon J, Nagaraja S, Morris PJ, Quezada M, Gillespie SM, Duveau DY, Michalowski AM, Shinn P, Guha R, Ferrer M, Klumpp-Thomas C, Michael S, McKnight C, Minhas P, Itkin Z, Raabe EH, Chen L, Ghanem R, Geraghty AC, Ni L, Andreasson KI, Vitanza NA, Warren KE, Thomas CJ, Monje M. Lin GL, et al. Among authors: itkin z. Sci Transl Med. 2019 Nov 20;11(519):eaaw0064. doi: 10.1126/scitranslmed.aaw0064. Sci Transl Med. 2019. PMID: 31748226 Free PMC article.
High-Throughput Screening for Drug Combinations.
Shinn P, Chen L, Ferrer M, Itkin Z, Klumpp-Thomas C, McKnight C, Michael S, Mierzwa T, Thomas C, Wilson K, Guha R. Shinn P, et al. Among authors: itkin z. Methods Mol Biol. 2019;1939:11-35. doi: 10.1007/978-1-4939-9089-4_2. Methods Mol Biol. 2019. PMID: 30848454
The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators.
Gorshkov K, Chen CZ, Bostwick R, Rasmussen L, Xu M, Pradhan M, Tran BN, Zhu W, Shamim K, Huang W, Hu X, Shen M, Klumpp-Thomas C, Itkin Z, Shinn P, Simeonov A, Michael S, Hall MD, Lo DC, Zheng W. Gorshkov K, et al. Among authors: itkin z. bioRxiv. 2020 May 28:2020.05.16.091520. doi: 10.1101/2020.05.16.091520. Preprint. bioRxiv. 2020. PMID: 32511355 Free PMC article. Updated.
Synergistic and Antagonistic Drug Combinations against SARS-CoV-2.
Bobrowski T, Chen L, Eastman RT, Itkin Z, Shinn P, Chen CZ, Guo H, Zheng W, Michael S, Simeonov A, Hall MD, Zakharov AV, Muratov EN. Bobrowski T, et al. Among authors: itkin z. Mol Ther. 2021 Feb 3;29(2):873-885. doi: 10.1016/j.ymthe.2020.12.016. Epub 2020 Dec 15. Mol Ther. 2021. PMID: 33333292 Free PMC article.
An OpenData portal to share COVID-19 drug repurposing data in real time.
Brimacombe KR, Zhao T, Eastman RT, Hu X, Wang K, Backus M, Baljinnyam B, Chen CZ, Chen L, Eicher T, Ferrer M, Fu Y, Gorshkov K, Guo H, Hanson QM, Itkin Z, Kales SC, Klumpp-Thomas C, Lee EM, Michael S, Mierzwa T, Patt A, Pradhan M, Renn A, Shinn P, Shrimp JH, Viraktamath A, Wilson KM, Xu M, Zakharov AV, Zhu W, Zheng W, Simeonov A, Mathé EA, Lo DC, Hall MD, Shen M. Brimacombe KR, et al. Among authors: itkin z. bioRxiv. 2020 Jun 5:2020.06.04.135046. doi: 10.1101/2020.06.04.135046. Preprint. bioRxiv. 2020. PMID: 32511420 Free PMC article.
Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.
Chen CZ, Shinn P, Itkin Z, Eastman RT, Bostwick R, Rasmussen L, Huang R, Shen M, Hu X, Wilson KM, Brooks B, Guo H, Zhao T, Klump-Thomas C, Simeonov A, Michael SG, Lo DC, Hall MD, Zheng W. Chen CZ, et al. Among authors: itkin z. bioRxiv. 2020 Aug 18:2020.08.18.255877. doi: 10.1101/2020.08.18.255877. Preprint. bioRxiv. 2020. PMID: 32839771 Free PMC article. Updated.
The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules.
Gorshkov K, Chen CZ, Bostwick R, Rasmussen L, Tran BN, Cheng YS, Xu M, Pradhan M, Henderson M, Zhu W, Oh E, Susumu K, Wolak M, Shamim K, Huang W, Hu X, Shen M, Klumpp-Thomas C, Itkin Z, Shinn P, Carlos de la Torre J, Simeonov A, Michael SG, Hall MD, Lo DC, Zheng W. Gorshkov K, et al. Among authors: itkin z. ACS Infect Dis. 2020 Dec 21:acsinfecdis.0c00349. doi: 10.1021/acsinfecdis.0c00349. Online ahead of print. ACS Infect Dis. 2020. PMID: 33346633 Free PMC article.
Modulation of Triple Artemisinin-Based Combination Therapy Pharmacodynamics by Plasmodium falciparum Genotype.
Ansbro MR, Itkin Z, Chen L, Zahoranszky-Kohalmi G, Amaratunga C, Miotto O, Peryea T, Hobbs CV, Suon S, Sá JM, Dondorp AM, van der Pluijm RW, Wellems TE, Simeonov A, Eastman RT. Ansbro MR, et al. Among authors: itkin z. ACS Pharmacol Transl Sci. 2020 Nov 2;3(6):1144-1157. doi: 10.1021/acsptsci.0c00110. eCollection 2020 Dec 11. ACS Pharmacol Transl Sci. 2020. PMID: 33344893
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