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2016 1
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2019 2
2020 8
2021 2
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14 results
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Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
Mathew D, Giles JR, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Ramage H, Cherry S, Hensley SE, Apostolidis SA, Huang AC, Vella LA; UPenn COVID Processing Unit, Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: ittner cag. Science. 2020 Sep 4;369(6508):eabc8511. doi: 10.1126/science.abc8511. Epub 2020 Jul 15. Science. 2020. PMID: 32669297 Free PMC article.
Comprehensive mapping of immune perturbations associated with severe COVID-19.
Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum RS, Mathew D, Baxter AE, Vella LA, Kuthuru O, Apostolidis SA, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR. Kuri-Cervantes L, et al. Among authors: ittner cag. Sci Immunol. 2020 Jul 15;5(49):eabd7114. doi: 10.1126/sciimmunol.abd7114. Sci Immunol. 2020. PMID: 32669287 Free PMC article.
Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection.
Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum R, Mathew D, Baxter AE, Vella L, Kuthuru O, Apostolidis S, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR. Kuri-Cervantes L, et al. Among authors: ittner cag. bioRxiv. 2020 May 18:2020.05.18.101717. doi: 10.1101/2020.05.18.101717. Preprint. bioRxiv. 2020. PMID: 32511394 Free PMC article.
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions.
Mathew D, Giles JR, Baxter AE, Greenplate AR, Wu JE, Alanio C, Oldridge DA, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Hensley SE, Apostolidis S, Huang AC, Vella LA; UPenn COVID Processing Unit, Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: ittner cag. bioRxiv. 2020 May 23:2020.05.20.106401. doi: 10.1101/2020.05.20.106401. Preprint. bioRxiv. 2020. PMID: 32511371 Free PMC article. Updated.
Erythrocytes Reveal Complement Activation in Patients with COVID-19.
Lam LM, Murphy SJ, Kuri-Cervantes L, Weisman AR, Ittner CAG, Reilly JP, Pampena MB, Betts MR, Wherry EJ, Song WC, Lambris JD, Cines DB, Meyer NJ, Mangalmurti NS. Lam LM, et al. Among authors: ittner cag. medRxiv. 2020 May 22:2020.05.20.20104398. doi: 10.1101/2020.05.20.20104398. Preprint. medRxiv. 2020. PMID: 32511554 Free PMC article.
Plasma Mitochondrial DNA Levels Are Associated With ARDS in Trauma and Sepsis Patients.
Faust HE, Reilly JP, Anderson BJ, Ittner CAG, Forker CM, Zhang P, Weaver BA, Holena DN, Lanken PN, Christie JD, Meyer NJ, Mangalmurti NS, Shashaty MGS. Faust HE, et al. Among authors: ittner cag. Chest. 2020 Jan;157(1):67-76. doi: 10.1016/j.chest.2019.09.028. Epub 2019 Oct 14. Chest. 2020. PMID: 31622590 Free PMC article.
Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis.
Reilly JP, Wang F, Jones TK, Palakshappa JA, Anderson BJ, Shashaty MGS, Dunn TG, Johansson ED, Riley TR, Lim B, Abbott J, Ittner CAG, Cantu E, Lin X, Mikacenic C, Wurfel MM, Christiani DC, Calfee CS, Matthay MA, Christie JD, Feng R, Meyer NJ. Reilly JP, et al. Among authors: ittner cag. Intensive Care Med. 2018 Nov;44(11):1849-1858. doi: 10.1007/s00134-018-5328-0. Epub 2018 Oct 21. Intensive Care Med. 2018. PMID: 30343317 Free PMC article.
Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study.
Guillen-Guio B, Lorenzo-Salazar JM, Ma SF, Hou PC, Hernandez-Beeftink T, Corrales A, García-Laorden MI, Jou J, Espinosa E, Muriel A, Domínguez D, Lorente L, Martín MM, Rodríguez-Gallego C, Solé-Violán J, Ambrós A, Carriedo D, Blanco J, Añón JM, Reilly JP, Jones TK, Ittner CA, Feng R, Schöneweck F, Kiehntopf M, Noth I, Scholz M, Brunkhorst FM, Scherag A, Meyer NJ, Villar J, Flores C. Guillen-Guio B, et al. Among authors: ittner ca. Lancet Respir Med. 2020 Mar;8(3):258-266. doi: 10.1016/S2213-2600(19)30368-6. Epub 2020 Jan 23. Lancet Respir Med. 2020. PMID: 31982041 Free PMC article.
Plasma sRAGE Acts as a Genetically Regulated Causal Intermediate in Sepsis-associated Acute Respiratory Distress Syndrome.
Jones TK, Feng R, Kerchberger VE, Reilly JP, Anderson BJ, Shashaty MGS, Wang F, Dunn TG, Riley TR, Abbott J, Ittner CAG, Christiani DC, Mikacenic C, Wurfel MM, Ware LB, Calfee CS, Matthay MA, Christie JD, Meyer NJ. Jones TK, et al. Among authors: ittner cag. Am J Respir Crit Care Med. 2020 Jan 1;201(1):47-56. doi: 10.1164/rccm.201810-2033OC. Am J Respir Crit Care Med. 2020. PMID: 31487195 Free PMC article.
Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study.
Shashaty MGS, Reilly JP, Faust HE, Forker CM, Ittner CAG, Zhang PX, Hotz MJ, Fitzgerald D, Yang W, Anderson BJ, Holena DN, Lanken PN, Christie JD, Meyer NJ, Mangalmurti NS. Shashaty MGS, et al. Among authors: ittner cag. Crit Care. 2019 Jun 28;23(1):235. doi: 10.1186/s13054-019-2482-x. Crit Care. 2019. PMID: 31253195 Free PMC article.
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