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Page 1
Saturation variant interpretation using CRISPR prime editing.
Erwood S, Bily TMI, Lequyer J, Yan J, Gulati N, Brewer RA, Zhou L, Pelletier L, Ivakine EA, Cohn RD. Erwood S, et al. Among authors: ivakine ea. Nat Biotechnol. 2022 Jun;40(6):885-895. doi: 10.1038/s41587-021-01201-1. Epub 2022 Feb 21. Nat Biotechnol. 2022. PMID: 35190686
An optimized toolkit for prime editing.
Marks RM, Scott O, Ivakine EA, Cohn RD. Marks RM, et al. Among authors: ivakine ea. Nat Biotechnol. 2024 Feb;42(2):187-189. doi: 10.1038/s41587-023-02091-1. Nat Biotechnol. 2024. PMID: 38287161 No abstract available.
Efficient prime editing in two-cell mouse embryos using PEmbryo.
Kim-Yip RP, McNulty R, Joyce B, Mollica A, Chen PJ, Ravisankar P, Law BK, Liu DR, Toettcher JE, Ivakine EA, Posfai E, Adamson B. Kim-Yip RP, et al. Among authors: ivakine ea. Nat Biotechnol. 2024 Feb 6. doi: 10.1038/s41587-023-02106-x. Online ahead of print. Nat Biotechnol. 2024. PMID: 38321114
Saturation genome editing maps the functional spectrum of pathogenic VHL alleles.
Buckley M, Terwagne C, Ganner A, Cubitt L, Brewer R, Kim DK, Kajba CM, Forrester N, Dace P, De Jonghe J, Shepherd STC, Sawyer C, McEwen M, Diederichs S, Neumann-Haefelin E, Turajlic S, Ivakine EA, Findlay GM. Buckley M, et al. Among authors: ivakine ea. Nat Genet. 2024 Jul;56(7):1446-1455. doi: 10.1038/s41588-024-01800-z. Epub 2024 Jul 5. Nat Genet. 2024. PMID: 38969834 Free PMC article.
A new mouse model of ATR-X syndrome carrying a common patient mutation exhibits neurological and morphological defects.
Tillotson R, Yan K, Ruston J, DeYoung T, Córdova A, Turcotte-Cardin V, Yee Y, Taylor C, Visuvanathan S, Babbs C, Ivakine EA, Sled JG, Nieman BJ, Picketts DJ, Justice MJ. Tillotson R, et al. Among authors: ivakine ea. Hum Mol Genet. 2023 Jul 20;32(15):2485-2501. doi: 10.1093/hmg/ddad075. Hum Mol Genet. 2023. PMID: 37171606 Free PMC article.
The human Stat1 gain-of-function T385M mutation causes expansion of activated T-follicular helper/T-helper 1-like CD4 T cells and sex-biased autoimmunity in specific pathogen-free mice.
Scott O, Visuvanathan S, Reddy E, Mahamed D, Gu B, Roifman CM, Cohn RD, Guidos CJ, Ivakine EA. Scott O, et al. Among authors: ivakine ea. Front Immunol. 2023 May 19;14:1183273. doi: 10.3389/fimmu.2023.1183273. eCollection 2023. Front Immunol. 2023. PMID: 37275873 Free PMC article.
30 results