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Page 1
Saturation genome editing maps the functional spectrum of pathogenic VHL alleles.
Buckley M, Terwagne C, Ganner A, Cubitt L, Brewer R, Kim DK, Kajba CM, Forrester N, Dace P, De Jonghe J, Shepherd STC, Sawyer C, McEwen M, Diederichs S, Neumann-Haefelin E, Turajlic S, Ivakine EA, Findlay GM. Buckley M, et al. Among authors: ivakine ea. Nat Genet. 2024 Jul;56(7):1446-1455. doi: 10.1038/s41588-024-01800-z. Epub 2024 Jul 5. Nat Genet. 2024. PMID: 38969834 Free PMC article.
Efficient prime editing in two-cell mouse embryos using PEmbryo.
Kim-Yip RP, McNulty R, Joyce B, Mollica A, Chen PJ, Ravisankar P, Law BK, Liu DR, Toettcher JE, Ivakine EA, Posfai E, Adamson B. Kim-Yip RP, et al. Among authors: ivakine ea. Nat Biotechnol. 2024 Dec;42(12):1822-1830. doi: 10.1038/s41587-023-02106-x. Epub 2024 Feb 6. Nat Biotechnol. 2024. PMID: 38321114 Free PMC article.
An optimized toolkit for prime editing.
Marks RM, Scott O, Ivakine EA, Cohn RD. Marks RM, et al. Among authors: ivakine ea. Nat Biotechnol. 2024 Feb;42(2):187-189. doi: 10.1038/s41587-023-02091-1. Nat Biotechnol. 2024. PMID: 38287161 No abstract available.
Saturation variant interpretation using CRISPR prime editing.
Erwood S, Bily TMI, Lequyer J, Yan J, Gulati N, Brewer RA, Zhou L, Pelletier L, Ivakine EA, Cohn RD. Erwood S, et al. Among authors: ivakine ea. Nat Biotechnol. 2022 Jun;40(6):885-895. doi: 10.1038/s41587-021-01201-1. Epub 2022 Feb 21. Nat Biotechnol. 2022. PMID: 35190686
Mutations in the β-tubulin TUBB impair ciliogenesis and are associated with ciliopathy-like phenotypes.
Mollica A, Omer S, Forguson G, Steiman S, Evagelou SL, Naumenko S, Walker S, Li LY, Teeling A, Lindsay K, Erwood S, Visuvanathan S, Vig A, Vernon RM, Akman B, Smith-Hicks C, Forman-Kay JD, Shroff M, Pai V, Harrison RE, Cohn RD, Ivakine EA. Mollica A, et al. Among authors: ivakine ea. Nat Commun. 2025 Nov 27;16(1):10637. doi: 10.1038/s41467-025-65634-x. Nat Commun. 2025. PMID: 41309602 Free PMC article.
34 results