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Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process.

Caudle KE, Klein TE, Hoffman JM, Muller DJ, Whirl-Carrillo M, Gong L, McDonagh EM, Sangkuhl K, Thorn CF, Schwab M, Agundez JA, Freimuth RR, Huser V, Lee MT, Iwuchukwu OF, Crews KR, Scott SA, Wadelius M, Swen JJ, Tyndale RF, Stein CM, Roden D, Relling MV, Williams MS, Johnson SG. Caudle KE, et al. Among authors: iwuchukwu of. Curr Drug Metab. 2014 Feb;15(2):209-17. doi: 10.2174/1389200215666140130124910. Curr Drug Metab. 2014. PMID: 24479687 Free PMC article.

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy.

Desta Z, Gammal RS, Gong L, Whirl-Carrillo M, Gaur AH, Sukasem C, Hockings J, Myers A, Swart M, Tyndale RF, Masimirembwa C, Iwuchukwu OF, Chirwa S, Lennox J, Gaedigk A, Klein TE, Haas DW. Desta Z, et al. Among authors: iwuchukwu of. Clin Pharmacol Ther. 2019 Oct;106(4):726-733. doi: 10.1002/cpt.1477. Epub 2019 Jul 5. Clin Pharmacol Ther. 2019. PMID: 31006110 Free PMC article.

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Using Personalized Medicine in the Management of Diabetes Mellitus.

Elk N, Iwuchukwu OF. Elk N, et al. Among authors: iwuchukwu of. Pharmacotherapy. 2017 Sep;37(9):1131-1149. doi: 10.1002/phar.1976. Epub 2017 Aug 15. Pharmacotherapy. 2017. PMID: 28654165 Review.

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Update on tools for evaluation of uridine diphosphoglucuronosyltransferase polymorphisms.

Argikar UA, Iwuchukwu OF, Nagar S. Argikar UA, et al. Among authors: iwuchukwu of. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):879-94. doi: 10.1517/17425255.4.7.879. Expert Opin Drug Metab Toxicol. 2008. PMID: 18624677 Review.

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing.

Gammal RS, Court MH, Haidar CE, Iwuchukwu OF, Gaur AH, Alvarellos M, Guillemette C, Lennox JL, Whirl-Carrillo M, Brummel SS, Ratain MJ, Klein TE, Schackman BR, Caudle KE, Haas DW; Clinical Pharmacogenetics Implementation Consortium. Gammal RS, et al. Among authors: iwuchukwu of. Clin Pharmacol Ther. 2016 Apr;99(4):363-9. doi: 10.1002/cpt.269. Epub 2015 Nov 9. Clin Pharmacol Ther. 2016. PMID: 26417955 Free PMC article. Review.

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In vivo-formed versus preformed metabolite kinetics of trans-resveratrol-3-sulfate and trans-resveratrol-3-glucuronide.

Sharan S, Iwuchukwu OF, Canney DJ, Zimmerman CL, Nagar S. Sharan S, et al. Among authors: iwuchukwu of. Drug Metab Dispos. 2012 Oct;40(10):1993-2001. doi: 10.1124/dmd.112.046417. Epub 2012 Jul 17. Drug Metab Dispos. 2012. PMID: 22807110 Free PMC article.

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Analytical method development for synthesized conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies.

Iwuchukwu OF, Sharan S, Canney DJ, Nagar S. Iwuchukwu OF, et al. J Pharm Biomed Anal. 2012 Apr 7;63:1-8. doi: 10.1016/j.jpba.2011.12.006. Epub 2011 Dec 16. J Pharm Biomed Anal. 2012. PMID: 22342060 Free PMC article.

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Genetic determinants of variability in warfarin response after the dose-titration phase.

Iwuchukwu OF, Ramirez AH, Shi Y, Bowton EA, Kawai VK, Schildcrout JS, Roden DM, Denny JC, Stein CM. Iwuchukwu OF, et al. Pharmacogenet Genomics. 2016 Nov;26(11):510-516. doi: 10.1097/FPC.0000000000000244. Pharmacogenet Genomics. 2016. PMID: 27632229 Free PMC article.

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Characterization of statin dose response in electronic medical records.

Wei WQ, Feng Q, Jiang L, Waitara MS, Iwuchukwu OF, Roden DM, Jiang M, Xu H, Krauss RM, Rotter JI, Nickerson DA, Davis RL, Berg RL, Peissig PL, McCarty CA, Wilke RA, Denny JC. Wei WQ, et al. Among authors: iwuchukwu of. Clin Pharmacol Ther. 2014 Mar;95(3):331-8. doi: 10.1038/clpt.2013.202. Epub 2013 Oct 4. Clin Pharmacol Ther. 2014. PMID: 24096969 Free PMC article.

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Creation and Validation of an EMR-based Algorithm for Identifying Major Adverse Cardiac Events while on Statins.

Wei WQ, Feng Q, Weeke P, Bush W, Waitara MS, Iwuchukwu OF, Roden DM, Wilke RA, Stein CM, Denny JC. Wei WQ, et al. Among authors: iwuchukwu of. AMIA Jt Summits Transl Sci Proc. 2014 Apr 7;2014:112-9. eCollection 2014. AMIA Jt Summits Transl Sci Proc. 2014. PMID: 25717410 Free PMC article.

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