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Page 1
Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest.
Eastwood G, Nichol AD, Hodgson C, Parke RL, McGuinness S, Nielsen N, Bernard S, Skrifvars MB, Stub D, Taccone FS, Archer J, Kutsogiannis D, Dankiewicz J, Lilja G, Cronberg T, Kirkegaard H, Capellier G, Landoni G, Horn J, Olasveengen T, Arabi Y, Chia YW, Markota A, Hænggi M, Wise MP, Grejs AM, Christensen S, Munk-Andersen H, Granfeldt A, Andersen GØ, Qvigstad E, Flaa A, Thomas M, Sweet K, Bewley J, Bäcklund M, Tiainen M, Iten M, Levis A, Peck L, Walsham J, Deane A, Ghosh A, Annoni F, Chen Y, Knight D, Lesona E, Tlayjeh H, Svenšek F, McGuigan PJ, Cole J, Pogson D, Hilty MP, Düring JP, Bailey MJ, Paul E, Ady B, Ainscough K, Hunt A, Monahan S, Trapani T, Fahey C, Bellomo R; TAME Study Investigators. Eastwood G, et al. N Engl J Med. 2023 Jul 6;389(1):45-57. doi: 10.1056/NEJMoa2214552. Epub 2023 Jun 15. N Engl J Med. 2023. PMID: 37318140 Clinical Trial.
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA.
Dmytrenko O, Neumann GC, Hallmark T, Keiser DJ, Crowley VM, Vialetto E, Mougiakos I, Wandera KG, Domgaard H, Weber J, Gaudin T, Metcalf J, Gray BN, Begemann MB, Jackson RN, Beisel CL. Dmytrenko O, et al. Nature. 2023 Jan;613(7944):588-594. doi: 10.1038/s41586-022-05559-3. Epub 2023 Jan 4. Nature. 2023. PMID: 36599979 Free PMC article.
Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies.
Fernbach S, Mair NK, Abela IA, Groen K, Kuratli R, Lork M, Thorball CW, Bernasconi E, Filippidis P, Leuzinger K, Notter J, Rauch A, Hirsch HH, Huber M, Günthard HF, Fellay J, Kouyos RD, Hale BG; Swiss HIV Cohort Study. Fernbach S, et al. J Exp Med. 2024 Sep 2;221(9):e20240365. doi: 10.1084/jem.20240365. Epub 2024 Jul 17. J Exp Med. 2024. PMID: 39017930 Free PMC article.
Comparison of Different Functional Tests for Leg Power and Normative Bilateral Asymmetry Index in Healthy Collegiate Athletes.
Sullivan SW, Fleet NA, Brooks VA, Bido J, Nwachukwu BU, Brubaker PH. Sullivan SW, et al. Open Access J Sports Med. 2021 Aug 6;12:119-128. doi: 10.2147/OAJSM.S315162. eCollection 2021. Open Access J Sports Med. 2021. PMID: 34393525 Free PMC article.
As an injury predictor, leg power is accurately measured with the Keiser Air420 seated leg press. PURPOSE: To measure and analyze lower leg asymmetry in healthy collegiate athletes across each test battery. ...The mean absolute BAI were 5.42 4.9%, 6.64 4.9% and 5.36 4.7% f …
As an injury predictor, leg power is accurately measured with the Keiser Air420 seated leg press. PURPOSE: To measure and analyze low …
The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer).
Olliaro P, Delgado-Romero P, Keiser J. Olliaro P, et al. J Antimicrob Chemother. 2014 Apr;69(4):863-70. doi: 10.1093/jac/dkt491. Epub 2014 Jan 2. J Antimicrob Chemother. 2014. PMID: 24390933 Review.
In addition, preschool-aged children are now recognized as a vulnerable population and a group for targeted treatment, but they may be difficult to dose correctly with the available product--a racemate, based on the biologically active enantiomer (R-praziquantel) and the i …
In addition, preschool-aged children are now recognized as a vulnerable population and a group for targeted treatment, but they may be diffi …
Type I interferon autoantibody footprints reveal neutralizing mechanisms and allow inhibitory decoy design.
Groen K, Kuratli R, Enkelmann J, Fernbach S, Wendel-Garcia PD, Staiger WI, Lejeune M, Sauras-Colón E, Roche-Campo F, Filippidis P, Rauch A; Swiss HIV Cohort Study; Trkola A, Günthard HF, Kouyos RD, Brugger SD, Hale BG. Groen K, et al. J Exp Med. 2025 Jun 2;222(6):e20242039. doi: 10.1084/jem.20242039. Epub 2025 Mar 20. J Exp Med. 2025. PMID: 40111224 Free PMC article.
Circulating HBV RNA and Hepatitis B Core-Related Antigen Trajectories in Persons With HIV/HBV Coinfection and Hepatitis B Surface Antigen Loss During Tenofovir Therapy.
Begré L, Boyd A, Plissonnier ML, Testoni B, Salazar-Vizcaya L, Suter-Riniker F, Scholtès C, Béguelin C, Rockstroh JK, Günthard HF, Calmy A, Cavassini M, Hirsch HH, Schmid P, Bernasconi E, Levrero M, Wandeler G, Zoulim F, Rauch A; Swiss HIV Cohort Study. Begré L, et al. J Infect Dis. 2024 Oct 16;230(4):e954-e963. doi: 10.1093/infdis/jiae189. J Infect Dis. 2024. PMID: 38626170 Free PMC article.
Prioritizing Virtual Screening with Interpretable Interaction Fingerprints.
Fassio AV, Shub L, Ponzoni L, McKinley J, O'Meara MJ, Ferreira RS, Keiser MJ, de Melo Minardi RC. Fassio AV, et al. J Chem Inf Model. 2022 Sep 26;62(18):4300-4318. doi: 10.1021/acs.jcim.2c00695. Epub 2022 Sep 14. J Chem Inf Model. 2022. PMID: 36102784
First, we trained machine learning models to reproduce DOCK3.7 scores using 1 million docked Dopamine D4 complexes. We found that EIFP-4,096 performed (R(2) = 0.61) superior to related molecular and interaction fingerprints. Second, we used LUNA to support interpretable ma …
First, we trained machine learning models to reproduce DOCK3.7 scores using 1 million docked Dopamine D4 complexes. We found that EIFP-4,096 …
Antibody and T-Cell Response to Bivalent Booster SARS-CoV-2 Vaccines in People With Compromised Immune Function: COVERALL-3 Study.
Amstutz A, Chammartin F, Audigé A, Eichenberger AL, Braun DL, Amico P, Stoeckle MP, Hasse B, Papadimitriou-Olivgeris M, Manuel O, Bongard C, Schuurmans MM, Hage R, Damm D, Tamm M, Mueller NJ, Rauch A, Günthard HF, Koller MT, Schönenberger CM, Griessbach A, Labhardt ND, Kouyos RD, Trkola A, Kusejko K, Bucher HC, Abela IA, Briel M, Speich B; Swiss HIV Cohort Study; Swiss Transplant Cohort. Amstutz A, et al. J Infect Dis. 2024 Oct 16;230(4):e847-e859. doi: 10.1093/infdis/jiae291. J Infect Dis. 2024. PMID: 38848312 Free PMC article. Clinical Trial.
Reliability and Validity of Different Lower-Limb Strength Tests to Determine 1RM in the Keiser A300 Leg Press.
Larsen F, Loturco I, Sigvaldsen E, Strand MF, Kalhovde JM, Haugen T. Larsen F, et al. J Strength Cond Res. 2023 Oct 1;37(10):1963-1968. doi: 10.1519/JSC.0000000000004516. J Strength Cond Res. 2023. PMID: 37729511
Reliability and validity of different lower-limb strength tests to determine 1RM in the Keiser A300 leg press. J Strength Cond Res 37(10): 1963-1968, 2023-The aim of this study was to explore the reliability and validity of different lower-limb strength tests to det …
Reliability and validity of different lower-limb strength tests to determine 1RM in the Keiser A300 leg press. J Strength Cond …
68 results