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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1980 1
1981 1
1982 2
1999 1
2000 1
2002 3
2003 1
2004 4
2005 4
2006 12
2007 11
2008 8
2009 11
2010 9
2011 13
2012 11
2013 19
2014 13
2015 11
2016 12
2017 8
2018 7
2019 10
2020 6
2021 14
2022 5
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Search Results

190 results
Results by year
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Page 1
Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Xia S, Zhang Z, Magupalli VG, Pablo JL, Dong Y, Vora SM, Wang L, Fu TM, Jacobson MP, Greka A, Lieberman J, Ruan J, Wu H. Xia S, et al. Among authors: jacobson mp. Nature. 2021 May;593(7860):607-611. doi: 10.1038/s41586-021-03478-3. Epub 2021 Apr 21. Nature. 2021. PMID: 33883744 Free PMC article.
Dysregulated pH: a perfect storm for cancer progression.
Webb BA, Chimenti M, Jacobson MP, Barber DL. Webb BA, et al. Among authors: jacobson mp. Nat Rev Cancer. 2011 Aug 11;11(9):671-7. doi: 10.1038/nrc3110. Nat Rev Cancer. 2011. PMID: 21833026 Review.
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.
Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, Hellerstein M, Goetzman ES, Gibson BW, Verdin E. Rardin MJ, et al. Among authors: jacobson mp. Cell Metab. 2013 Dec 3;18(6):920-33. doi: 10.1016/j.cmet.2013.11.013. Cell Metab. 2013. PMID: 24315375 Free PMC article.
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor.
Fink EA, Xu J, Hübner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. Fink EA, et al. Among authors: jacobson mp. Science. 2022 Sep 30;377(6614):eabn7065. doi: 10.1126/science.abn7065. Epub 2022 Sep 30. Science. 2022. PMID: 36173843
Computer-aided antibody design.
Kuroda D, Shirai H, Jacobson MP, Nakamura H. Kuroda D, et al. Among authors: jacobson mp. Protein Eng Des Sel. 2012 Oct;25(10):507-21. doi: 10.1093/protein/gzs024. Epub 2012 Jun 2. Protein Eng Des Sel. 2012. PMID: 22661385 Free PMC article. Review.
Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium.
Pikman Y, Tasian SK, Sulis ML, Stevenson K, Blonquist TM, Apsel Winger B, Cooper TM, Pauly M, Maloney KW, Burke MJ, Brown PA, Gossai N, McNeer JL, Shukla NN, Cole PD, Kahn JM, Chen J, Barth MJ, Magee JA, Gennarini L, Adhav AA, Clinton CM, Ocasio-Martinez N, Gotti G, Li Y, Lin S, Imamovic A, Tognon CE, Patel T, Faust HL, Contreras CF, Cremer A, Cortopassi WA, Garrido Ruiz D, Jacobson MP, Dharia NV, Su A, Robichaud AL, Saur Conway A, Tarlock K, Stieglitz E, Place AE, Puissant A, Hunger SP, Kim AS, Lindeman NI, Gore L, Janeway KA, Silverman LB, Tyner JW, Harris MH, Loh ML, Stegmaier K. Pikman Y, et al. Among authors: jacobson mp. Cancer Discov. 2021 Jun;11(6):1424-1439. doi: 10.1158/2159-8290.CD-20-0564. Epub 2021 Feb 9. Cancer Discov. 2021. PMID: 33563661 Free PMC article. Clinical Trial.
Designing molecules to cross biological membranes.
Lokey RS, Liras J, Liras S, Jacobson MP. Lokey RS, et al. Among authors: jacobson mp. Curr Top Med Chem. 2013;13(7):775. doi: 10.2174/1568026611313070001. Curr Top Med Chem. 2013. PMID: 23578022 No abstract available.
The Enzyme Function Initiative.
Gerlt JA, Allen KN, Almo SC, Armstrong RN, Babbitt PC, Cronan JE, Dunaway-Mariano D, Imker HJ, Jacobson MP, Minor W, Poulter CD, Raushel FM, Sali A, Shoichet BK, Sweedler JV. Gerlt JA, et al. Among authors: jacobson mp. Biochemistry. 2011 Nov 22;50(46):9950-62. doi: 10.1021/bi201312u. Epub 2011 Oct 26. Biochemistry. 2011. PMID: 21999478 Free PMC article. Review.
A Crowding Barrier to Protein Inhibition in Colloidal Aggregates.
Lak P, O'Donnell H, Du X, Jacobson MP, Shoichet BK. Lak P, et al. Among authors: jacobson mp. J Med Chem. 2021 Apr 8;64(7):4109-4116. doi: 10.1021/acs.jmedchem.0c02253. Epub 2021 Mar 24. J Med Chem. 2021. PMID: 33761256 Free PMC article.
Synthesis and Screening of α-Xylosides in Human Glioblastoma Cells.
Kalita M, Villanueva-Meyer J, Ohkawa Y, Kalyanaraman C, Chen K, Mohamed E, Parker MFL, Jacobson MP, Phillips JJ, Evans MJ, Wilson DM. Kalita M, et al. Among authors: jacobson mp. Mol Pharm. 2021 Jan 4;18(1):451-460. doi: 10.1021/acs.molpharmaceut.0c00839. Epub 2020 Dec 14. Mol Pharm. 2021. PMID: 33315406 Free PMC article.
190 results