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2014 1
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2017 3
2018 1
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2023 2
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16 results

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Page 1
Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy.
Han H, Jain AD, Truica MI, Izquierdo-Ferrer J, Anker JF, Lysy B, Sagar V, Luan Y, Chalmers ZR, Unno K, Mok H, Vatapalli R, Yoo YA, Rodriguez Y, Kandela I, Parker JB, Chakravarti D, Mishra RK, Schiltz GE, Abdulkadir SA. Han H, et al. Among authors: jain ad. Cancer Cell. 2019 Nov 11;36(5):483-497.e15. doi: 10.1016/j.ccell.2019.10.001. Epub 2019 Oct 31. Cancer Cell. 2019. PMID: 31679823 Free PMC article.
Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway.
Richardson BG, Jain AD, Speltz TE, Moore TW. Richardson BG, et al. Among authors: jain ad. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2261-8. doi: 10.1016/j.bmcl.2015.04.019. Epub 2015 Apr 16. Bioorg Med Chem Lett. 2015. PMID: 25937010 Free PMC article. Review.
Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors.
Lazzara PR, Jain AD, Maldonado AC, Richardson B, Skowron KJ, David BP, Siddiqui Z, Ratia KM, Moore TW. Lazzara PR, et al. Among authors: jain ad. ACS Med Chem Lett. 2020 Feb 19;11(4):521-527. doi: 10.1021/acsmedchemlett.9b00631. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292559 Free PMC article.
Development of GLUT4-selective antagonists for multiple myeloma therapy.
Wei C, Bajpai R, Sharma H, Heitmeier M, Jain AD, Matulis SM, Nooka AK, Mishra RK, Hruz PW, Schiltz GE, Shanmugam M. Wei C, et al. Among authors: jain ad. Eur J Med Chem. 2017 Oct 20;139:573-586. doi: 10.1016/j.ejmech.2017.08.029. Epub 2017 Aug 14. Eur J Med Chem. 2017. PMID: 28837922 Free PMC article.
Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors.
Richardson BG, Jain AD, Potteti HR, Lazzara PR, David BP, Tamatam CR, Choma E, Skowron K, Dye K, Siddiqui Z, Wang YT, Krunic A, Reddy SP, Moore TW. Richardson BG, et al. Among authors: jain ad. J Med Chem. 2018 Sep 13;61(17):8029-8047. doi: 10.1021/acs.jmedchem.8b01133. Epub 2018 Aug 31. J Med Chem. 2018. PMID: 30122040 Free PMC article.
16 results