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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 2
2007 2
2008 4
2009 2
2010 7
2011 5
2012 6
2013 1
2014 4
2015 4
2016 1
2017 2
2019 1
2020 1
2022 2
2023 1
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42 results
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Functional genomics of human pre-implantation development.
Sudheer S, Adjaye J. Sudheer S, et al. Among authors: adjaye j. Brief Funct Genomic Proteomic. 2007 Jun;6(2):120-32. doi: 10.1093/bfgp/elm012. Epub 2007 Jul 31. Brief Funct Genomic Proteomic. 2007. PMID: 17670767 Review.
Mitochondrial function in pluripotent stem cells and cellular reprogramming.
Bukowiecki R, Adjaye J, Prigione A. Bukowiecki R, et al. Among authors: adjaye j. Gerontology. 2014;60(2):174-82. doi: 10.1159/000355050. Epub 2013 Nov 19. Gerontology. 2014. PMID: 24281332 Free article. Review.
Their loss of functionality may indeed contribute to the development of aging and age-related neurodegenerative disorders. Recently, mitochondria have been shown to exhibit peculiar features in pluripotent stem cells (PSCs). ...Here, we review these recent findings and dis …
Their loss of functionality may indeed contribute to the development of aging and age-related neurodegenerative disorders. Recently, …
Human skin stem cells and the ageing process.
Zouboulis CC, Adjaye J, Akamatsu H, Moe-Behrens G, Niemann C. Zouboulis CC, et al. Among authors: adjaye j. Exp Gerontol. 2008 Nov;43(11):986-97. doi: 10.1016/j.exger.2008.09.001. Epub 2008 Sep 9. Exp Gerontol. 2008. PMID: 18809487 Review.
Despite accumulation of senescence markers in aged skin, epidermal stem cells are maintained at normal levels throughout life. Therefore, skin ageing is induced by impaired stem cell mobilisation or reduced number of stem cells able to respond to proliferative signals. ... …
Despite accumulation of senescence markers in aged skin, epidermal stem cells are maintained at normal levels throughout life. Therefore, sk …
Skin and brain age together: The role of hormones in the ageing process.
Makrantonaki E, Schönknecht P, Hossini AM, Kaiser E, Katsouli MM, Adjaye J, Schröder J, Zouboulis CC. Makrantonaki E, et al. Among authors: adjaye j. Exp Gerontol. 2010 Oct;45(10):801-13. doi: 10.1016/j.exger.2010.08.005. Epub 2010 Aug 16. Exp Gerontol. 2010. PMID: 20719245 Review.
The importance of the endocrine environment in the initiation of the ageing process has been elucidated in several in vivo and in vitro studies. ...On the other hand, recent data suggest that skin is a window to the human organism and represents an adequate model for ag …
The importance of the endocrine environment in the initiation of the ageing process has been elucidated in several in vivo and in vit …
Crosstalk between age accumulated DNA-damage and the SIRT1-AKT-GSK3ß axis in urine derived renal progenitor cells.
Erichsen L, Adjaye J. Erichsen L, et al. Among authors: adjaye j. Aging (Albany NY). 2022 Sep 24;14(20):8179-8204. doi: 10.18632/aging.204300. Epub 2022 Sep 24. Aging (Albany NY). 2022. PMID: 36170022 Free PMC article.
The aging process is manifested by a multitude of inter-linked biological processes. ...Furthermore, we show that the SIRT1 promoter region is methylation sensitive and becomes methylated during aging, dividing them into SIRT1-high and -low expressing UdRPCs. ...
The aging process is manifested by a multitude of inter-linked biological processes. ...Furthermore, we show that the SIRT1 promoter …
Urine-Based Detection of Biomarkers Indicative of Chronic Kidney Disease in a Patient Cohort from Ghana.
Wruck W, Boima V, Erichsen L, Thimm C, Koranteng T, Kwakyi E, Antwi S, Adu D, Adjaye J. Wruck W, et al. Among authors: adjaye j. J Pers Med. 2022 Dec 24;13(1):38. doi: 10.3390/jpm13010038. J Pers Med. 2022. PMID: 36675700 Free PMC article.
Chronic kidney disease (CKD) is a global health burden with a continuously increasing prevalence associated with an increasing incidence of diabetes and hypertension in aging populations. CKD is characterized by low glomerular filtration rate (GFR) and other renal impairme …
Chronic kidney disease (CKD) is a global health burden with a continuously increasing prevalence associated with an increasing incidence of …
Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature.
Spitzhorn LS, Megges M, Wruck W, Rahman MS, Otte J, Degistirici Ö, Meisel R, Sorg RV, Oreffo ROC, Adjaye J. Spitzhorn LS, et al. Among authors: adjaye j. Stem Cell Res Ther. 2019 Mar 18;10(1):100. doi: 10.1186/s13287-019-1209-x. Stem Cell Res Ther. 2019. PMID: 30885246 Free PMC article.
BACKGROUND: Primary mesenchymal stem cells (MSCs) are fraught with aging-related shortfalls. Human-induced pluripotent stem cell (iPSC)-derived MSCs (iMSCs) have been shown to be a useful clinically relevant source of MSCs that circumvent these aging-associated draw …
BACKGROUND: Primary mesenchymal stem cells (MSCs) are fraught with aging-related shortfalls. Human-induced pluripotent stem cell (iPS …
42 results