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The multiple faces of quercetin in neuroprotection.

Ossola B, Kääriäinen TM, Männistö PT. Ossola B, et al. Among authors: kaariainen tm. Expert Opin Drug Saf. 2009 Jul;8(4):397-409. doi: 10.1517/14740330903026944. Expert Opin Drug Saf. 2009. PMID: 19538101 Review.

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Biochemical and Functional Characterization of the Trace Amine-Associated Receptor 1 (TAAR1) Agonist RO5263397.

Espinoza S, Leo D, Sotnikova TD, Shahid M, Kääriäinen TM, Gainetdinov RR. Espinoza S, et al. Among authors: kaariainen tm. Front Pharmacol. 2018 Jun 21;9:645. doi: 10.3389/fphar.2018.00645. eCollection 2018. Front Pharmacol. 2018. PMID: 29977204 Free PMC article.

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Brain pharmacokinetics of ganciclovir in rats with orthotopic BT4C glioma.

Gynther M, Kääriäinen TM, Hakkarainen JJ, Jalkanen AJ, Petsalo A, Lehtonen M, Peura L, Kurkipuro J, Samaranayake H, Ylä-Herttuala S, Rautio J, Forsberg MM. Gynther M, et al. Among authors: kaariainen tm. Drug Metab Dispos. 2015 Jan;43(1):140-6. doi: 10.1124/dmd.114.059840. Epub 2014 Oct 27. Drug Metab Dispos. 2015. PMID: 25349125

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Combined ipsilateral limb use score as an index of motor deficits and neurorestoration in parkinsonian rats.

Leikas JV, Kääriäinen TM, Jalkanen AJ, Lehtonen M, Rantamäki T, Forsberg MM. Leikas JV, et al. Among authors: kaariainen tm. J Neurosci Res. 2017 Sep;95(9):1858-1870. doi: 10.1002/jnr.24022. Epub 2017 Jan 30. J Neurosci Res. 2017. PMID: 28134996

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L-dopa-induced desensitization depends on 5-hydroxytryptamine imbalance in hemiparkinsonian rats.

Kääriäinen TM, García-Horsman JA, Piltonen M, Männistö PT. Kääriäinen TM, et al. Neuroreport. 2009 Feb 18;20(3):313-8. doi: 10.1097/WNR.0b013e328321e704. Neuroreport. 2009. PMID: 19188858

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Brain pharmacokinetics of two prolyl oligopeptidase inhibitors, JTP-4819 and KYP-2047, in the rat.

Jalkanen AJ, Hakkarainen JJ, Lehtonen M, Venäläinen T, Kääriäinen TM, Jarho E, Suhonen M, Forsberg MM. Jalkanen AJ, et al. Among authors: kaariainen tm. Basic Clin Pharmacol Toxicol. 2011 Dec;109(6):443-51. doi: 10.1111/j.1742-7843.2011.00747.x. Epub 2011 Jul 28. Basic Clin Pharmacol Toxicol. 2011. PMID: 21707925 Free article.

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Comparison of in vitro cell models in predicting in vivo brain entry of drugs.

Hakkarainen JJ, Jalkanen AJ, Kääriäinen TM, Keski-Rahkonen P, Venäläinen T, Hokkanen J, Mönkkönen J, Suhonen M, Forsberg MM. Hakkarainen JJ, et al. Among authors: kaariainen tm. Int J Pharm. 2010 Dec 15;402(1-2):27-36. doi: 10.1016/j.ijpharm.2010.09.016. Epub 2010 Oct 8. Int J Pharm. 2010. PMID: 20920560

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Localization of prolyl oligopeptidase in the thalamic and cortical projection neurons: a retrograde neurotracing study in the rat brain.

Myöhänen TT, Kääriäinen TM, Jalkanen AJ, Piltonen M, Männistö PT. Myöhänen TT, et al. Among authors: kaariainen tm. Neurosci Lett. 2009 Jan 30;450(2):201-5. doi: 10.1016/j.neulet.2008.11.038. Epub 2008 Nov 21. Neurosci Lett. 2009. PMID: 19041368

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Unpredictable rotational responses to L-dopa in the rat model of Parkinson's disease: the role of L-dopa pharmacokinetics and striatal dopamine depletion.

Kääriäinen TM, Käenmäki M, Forsberg MM, Oinas N, Tammimäki A, Männistö PT. Kääriäinen TM, et al. Basic Clin Pharmacol Toxicol. 2012 Feb;110(2):162-70. doi: 10.1111/j.1742-7843.2011.00782.x. Epub 2011 Sep 13. Basic Clin Pharmacol Toxicol. 2012. PMID: 21848668 Free article.

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Serotonergic activation after 2-week intrastriatal infusion of L-dopa and slow recovery of circling in rats with unilateral nigral lesions.

Kääriäinen TM, García-Horsman JA, Piltonen M, Huotari M, Männistö PT. Kääriäinen TM, et al. Basic Clin Pharmacol Toxicol. 2008 Mar;102(3):300-7. doi: 10.1111/j.1742-7843.2007.00153.x. Epub 2007 Oct 31. Basic Clin Pharmacol Toxicol. 2008. PMID: 17973898 Free article.

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