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2013 1
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Page 1
Identification of Omicron-Delta Coinfections Using PCR-Based Genotyping.
Roychoudhury P, Luo S, Hayashibara K, Hajian P, Mills MG, Lozach J, Cassens T, Wendm ST, Arnould I, Becker D, Wesselman T, Davis-Turak J, Creager R, Lai E, Jerome KR, Basler T, Dei Rossi A, Lee W, Greninger AL. Roychoudhury P, et al. Microbiol Spectr. 2022 Jun 29;10(3):e0060522. doi: 10.1128/spectrum.00605-22. Epub 2022 May 3. Microbiol Spectr. 2022. PMID: 35502920 Free PMC article. No abstract available.
Mechanisms of clinical resistance to selective FGFR2 inhibition by lirafugratinib.
Ellis H, Balasooriya ER, Varkaris A, Hajian B, Wan J, Shekhar M, Gritti I, Vijay V, Albertelli L, Piot S, Lau K, Kehlmann A, Chevalier N, Nugent FW, Zhen Y, Silveira VS, Sellers WR, Corcoran RB, Juric D, Bardeesy N. Ellis H, et al. Ann Oncol. 2026 Jun;37(6):798-812. doi: 10.1016/j.annonc.2026.01.004. Epub 2026 Jan 20. Ann Oncol. 2026. PMID: 41571046
Resistance profiles differed markedly from pan-FGFR inhibitors, with decreased FGFR2 V565F/L and N550H/K mutations, increased M538I and L618F mutations, and more frequent RTK-MAPK bypass alterations. ...
Resistance profiles differed markedly from pan-FGFR inhibitors, with decreased FGFR2 V565F/L and N550H/K mutations, increased M538I a …
Synthetic genomes unveil the effects of synonymous recoding.
Nyerges A, Chiappino-Pepe A, Budnik B, Baas-Thomas M, Flynn R, Yan S, Ostrov N, Liu M, Wang M, Zheng Q, Hu F, Chen K, Rudolph A, Chen D, Ahn J, Spencer O, Ayalavarapu V, Tarver A, Harmon-Smith M, Hamilton M, Blaby I, Yoshikuni Y, Hajian B, Jin A, Kintses B, Szamel M, Seregi V, Shen Y, Li Z, Church GM. Nyerges A, et al. bioRxiv [Preprint]. 2024 Jun 16:2024.06.16.599206. doi: 10.1101/2024.06.16.599206. bioRxiv. 2024. PMID: 38915524 Free PMC article. Preprint.
A synthesis of evidence for policy from behavioural science during COVID-19.
Ruggeri K, Stock F, Haslam SA, Capraro V, Boggio P, Ellemers N, Cichocka A, Douglas KM, Rand DG, van der Linden S, Cikara M, Finkel EJ, Druckman JN, Wohl MJA, Petty RE, Tucker JA, Shariff A, Gelfand M, Packer D, Jetten J, Van Lange PAM, Pennycook G, Peters E, Baicker K, Crum A, Weeden KA, Napper L, Tabri N, Zaki J, Skitka L, Kitayama S, Mobbs D, Sunstein CR, Ashcroft-Jones S, Todsen AL, Hajian A, Verra S, Buehler V, Friedemann M, Hecht M, Mobarak RS, Karakasheva R, Tünte MR, Yeung SK, Rosenbaum RS, Lep Ž, Yamada Y, Hudson STJ, Macchia L, Soboleva I, Dimant E, Geiger SJ, Jarke H, Wingen T, Berkessel JB, Mareva S, McGill L, Papa F, Većkalov B, Afif Z, Buabang EK, Landman M, Tavera F, Andrews JL, Bursalıoğlu A, Zupan Z, Wagner L, Navajas J, Vranka M, Kasdan D, Chen P, Hudson KR, Novak LM, Teas P, Rachev NR, Galizzi MM, Milkman KL, Petrović M, Van Bavel JJ, Willer R. Ruggeri K, et al. Nature. 2024 Jan;625(7993):134-147. doi: 10.1038/s41586-023-06840-9. Epub 2023 Dec 13. Nature. 2024. PMID: 38093007 Free PMC article.
A Molecular Dynamics Simulation Study of In- and Cross-Plane Thermal Conductivity of Bilayer Graphene.
Mohammadi R, Ghaderi MR, Hajian E. Mohammadi R, et al. Materials (Basel). 2023 Oct 16;16(20):6714. doi: 10.3390/ma16206714. Materials (Basel). 2023. PMID: 37895695 Free PMC article.
In addition, increasing temperature from 300 K to 600 K decreases the in-plane thermal conductivity of a 10 nm 10 nm zigzag BLG by about 34%. ...Furthermore, the cross-plane thermal conductivity of BLG at 300 K is estimated to be 0.05 W/m.K, signific …
In addition, increasing temperature from 300 K to 600 K decreases the in-plane thermal conductivity of a 10 nm 10 nm zigzag …
Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence.
Zhou J, Horton JR, Menna M, Fiorentino F, Ren R, Yu D, Hajian T, Vedadi M, Mazzoccanti G, Ciogli A, Weinhold E, Hüben M, Blumenthal RM, Zhang X, Mai A, Rotili D, Cheng X. Zhou J, et al. J Med Chem. 2023 Jan 12;66(1):934-950. doi: 10.1021/acs.jmedchem.2c01789. Epub 2022 Dec 29. J Med Chem. 2023. PMID: 36581322 Free PMC article.
The most potent of these inhibitors, compound 39 (IC(50) 0.4 muM and K(D) 0.2 muM), is selective for CamA against closely related bacterial and mammalian DNA and RNA adenine methyltransferases, protein lysine and arginine methyltransferases, and human adenosine recepto …
The most potent of these inhibitors, compound 39 (IC(50) 0.4 muM and K(D) 0.2 muM), is selective for CamA against closely related …
Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain.
Senisterra G, Zhu HY, Luo X, Zhang H, Xun G, Lu C, Xiao W, Hajian T, Loppnau P, Chau I, Li F, Allali-Hassani A, Atadja P, Oyang C, Li E, Brown PJ, Arrowsmith CH, Zhao K, Yu Z, Vedadi M. Senisterra G, et al. SLAS Discov. 2018 Oct;23(9):930-940. doi: 10.1177/2472555218766278. Epub 2018 Mar 21. SLAS Discov. 2018. PMID: 29562800 Free article.
This screen resulted in the identification of NV01, which bound to UHRF1-TTD with a K(d) value of 5 muM. The structure of UHRF1-TTD in complex with NV01 confirmed binding to the H3K9me3-binding pocket. Limited structure-based optimization of NV01 led to the discovery of NV …
This screen resulted in the identification of NV01, which bound to UHRF1-TTD with a K(d) value of 5 muM. The structure of UHRF1-TTD i …
Probing the limits of genetic recoding using multi-omics-guided evolution.
Nyerges A, Chiappino-Pepe A, Budnik B, Baas-Thomas M, Rhuby E, Flynn R, Yan S, Ostrov N, Liu M, Wang M, Zheng Q, Hu F, Chen K, Rudolph A, Chen D, Ahn J, Spencer O, Ayalavarapu V, Tarver A, Harmon-Smith M, Hamilton M, Blaby I, Yoshikuni Y, Hajian B, Jin A, Kintses B, Szamel M, Seregi V, Shen Y, Li Z, Church GM. Nyerges A, et al. Nat Commun. 2026 Jun 22;17(1):5311. doi: 10.1038/s41467-026-74300-9. Nat Commun. 2026. PMID: 42331836 Free PMC article.
Fabrication of an electrochemical sensor for determination of doxorubicin in human plasma and its interaction with DNA.
Hajian R, Tayebi Z, Shams N. Hajian R, et al. J Pharm Anal. 2017 Feb;7(1):27-33. doi: 10.1016/j.jpha.2016.07.005. Epub 2016 Jul 19. J Pharm Anal. 2017. PMID: 29404015 Free PMC article.
Moreover, cyclic voltammetry studies of DOX in the presence of DNA showed an intercalation mechanism with binding constant (K(b)) of 1.12 10(5) L/mol....
Moreover, cyclic voltammetry studies of DOX in the presence of DNA showed an intercalation mechanism with binding constant (K(b)) of …
15 results