Structural-functional interactions of NS1-BP protein with the splicing and mRNA export machineries for viral and host gene expression.
Zhang K, Shang G, Padavannil A, Wang J, Sakthivel R, Chen X, Kim M, Thompson MG, García-Sastre A, Lynch KW, Chen ZJ, Chook YM, Fontoura BMA.
Zhang K, et al.
Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12218-E12227. doi: 10.1073/pnas.1818012115. Epub 2018 Dec 11.
Proc Natl Acad Sci U S A. 2018.
PMID: 30538201
Free PMC article.
The central BACK domain of NS1-BP interacts directly with splicing factors such as hnRNP K and PTBP1 and with the viral NS1 protein. The BACK domain is also the site for interactions with mRNA export factor Aly/REF and is required for viral M mRNA nuclear export. .. …
The central BACK domain of NS1-BP interacts directly with splicing factors such as hnRNP K and PTBP1 and with the viral NS1 protein. …