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Anti-embolic and anti-oxidative effects of a novel (E)-4-amino-N'-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl) ethylidene) benzohydrazide against isoproterenol and vitamin-K induced ischemic stroke.
Mnafgui K, Khdhiri E, Ghazouani L, Ncir M, Zaafouri Z, Allouche N, Elfeki A, Ammar H, Abid S, Hajji R. Mnafgui K, et al. Arch Physiol Biochem. 2021 Dec;127(6):527-540. doi: 10.1080/13813455.2019.1657900. Epub 2019 Aug 30. Arch Physiol Biochem. 2021. PMID: 31469295
Overall, HC is endowed with a thrombolytic potential against MI and stroke in such severe conditions through an anti-vit K (AVK) mechanism....
Overall, HC is endowed with a thrombolytic potential against MI and stroke in such severe conditions through an anti-vit K (AVK) mech …
A novel synthetised sulphonylhydrazone coumarin (E)-4-methyl-N'-(1-(3-oxo-3H-benzo[f]chromen-2- yl)ethylidene)benzenesulphonohydrazide protect against isoproterenol-induced myocardial infarction in rats by attenuating oxidative damage, biological changes and electrocardiogram.
Ghazouani L, Khdhiri E, Elmufti A, Zarei A, Feriani A, Baaziz I, Hajji R, Abid M, Ammar H, Abid S, Allouche N, Mnafgui K, Ramazani A, Tlili N. Ghazouani L, et al. Clin Exp Pharmacol Physiol. 2022 Sep;49(9):1010-1026. doi: 10.1111/1440-1681.13690. Epub 2022 Jul 24. Clin Exp Pharmacol Physiol. 2022. PMID: 35717592
Furthermore, in silico analysis showed that 5,6-PhSHC possess high computational affinities (E-value >-9.0 kcal/mol) against cyclooxygenase-2 (PDB-ID: 1CX2), vitamin K epoxide reductase (PDB-ID: 3KP9), glycoprotein-IIb/IIIa (PDB-ID: 2VDM) and catalase (PDB-ID: 1DGF). .. …
Furthermore, in silico analysis showed that 5,6-PhSHC possess high computational affinities (E-value >-9.0 kcal/mol) against cyclooxygena …
Improving productivity and soil fertility in Medicago sativa and Hordeum marinum through intercropping under saline conditions.
Guerchi A, Mnafgui W, Jabri C, Merghni M, Sifaoui K, Mahjoub A, Ludidi N, Badri M. Guerchi A, et al. BMC Plant Biol. 2024 Mar 1;24(1):158. doi: 10.1186/s12870-024-04820-3. BMC Plant Biol. 2024. PMID: 38429693 Free PMC article.
Furthermore, both intercropping systems alleviated the nutrient uptake under salt stress, as noted by the highest levels of K(+)/Na(+) and Ca(2+)/Mg(2+) ratios compared to monoculture. However, the intercropping mode reduced the pH and the electroconductivity (CEC) of the …
Furthermore, both intercropping systems alleviated the nutrient uptake under salt stress, as noted by the highest levels of K(+)/Na(+ …
Inhibitory Activities of Zygophyllum album: A Natural Weight-Lowering Plant on Key Enzymes in High-Fat Diet-Fed Rats.
Mnafgui K, Hamden K, Ben Salah H, Kchaou M, Nasri M, Slama S, Derbali F, Allouche N, Elfeki A. Mnafgui K, et al. Evid Based Complement Alternat Med. 2012;2012:620384. doi: 10.1155/2012/620384. Epub 2012 Nov 8. Evid Based Complement Alternat Med. 2012. PMID: 23258993 Free PMC article.
Interestingly, supplementation of EZA modulated key enzyme related to hypertension such as ACE by 36% in serum of HFD animals and improve some of serum electrolytes such as Na(+), K(+), Cl(-), Ca(2+) and Mg(2+). Moreover, EZA significantly protected the liver-kidney functi …
Interestingly, supplementation of EZA modulated key enzyme related to hypertension such as ACE by 36% in serum of HFD animals and improve so …