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69 results

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Page 1
Characterization of the Small Bowel Microbiome Reveals Different Profiles in Human Subjects Who Are Overweight or Have Obesity.
Leite G, Barlow GM, Rashid M, Hosseini A, Cohrs D, Parodi G, Morales W, Weitsman S, Rezaie A, Pimentel M, Mathur R. Leite G, et al. Am J Gastroenterol. 2024 Jun 1;119(6):1141-1153. doi: 10.14309/ajg.0000000000002790. Epub 2024 Apr 5. Am J Gastroenterol. 2024. PMID: 38578969 Free PMC article.
Overweight-specific duodenal microbial features include lower relative abundance (RA) of Bifidobacterium species and Escherichia coli strain K-12 and higher Lactobacillus intestinalis , L. johnsonii , and Prevotella loescheii RA. ...
Overweight-specific duodenal microbial features include lower relative abundance (RA) of Bifidobacterium species and Escherichia coli strain …
Hybrid consensus and k-nearest neighbours (kNN) strategies to classify dual BRD4/PLK1 inhibitors.
Rezaie H, Asadollahi-Baboli M, Hassaninejad-Darzi SK. Rezaie H, et al. SAR QSAR Environ Res. 2022 Oct;33(10):779-792. doi: 10.1080/1062936X.2022.2139292. Epub 2022 Nov 4. SAR QSAR Environ Res. 2022. PMID: 36330747
A novel decision-making procedure is proposed here for the first time to identify active/inactive and selective/non-selective dual inhibitors using consensus approaches and pools of k-nearest neighbours (kNN) classifications instead of individual models. Dual BRD4/PLK1 inh …
A novel decision-making procedure is proposed here for the first time to identify active/inactive and selective/non-selective dual inhibitor …
Protease-activated receptor signalling by coagulation proteases in endothelial cells.
Rezaie AR. Rezaie AR. Thromb Haemost. 2014 Nov;112(5):876-82. doi: 10.1160/TH14-02-0167. Epub 2014 Jul 3. Thromb Haemost. 2014. PMID: 24990498 Free PMC article. Review.
A small family of G-protein coupled receptors, termed protease-activated receptors (PAR1-4), can be specifically activated by coagulation proteases, thereby modulating a diverse array of cellular activities under various pathophysiological conditions. Thrombin and all vitamin …
A small family of G-protein coupled receptors, termed protease-activated receptors (PAR1-4), can be specifically activated by coagulation pr …
Exosite-dependent regulation of the protein C anticoagulant pathway.
Rezaie AR. Rezaie AR. Trends Cardiovasc Med. 2003 Jan;13(1):8-15. doi: 10.1016/s1050-1738(02)00191-3. Trends Cardiovasc Med. 2003. PMID: 12554095 Review.
Activated protein C (APC) is a vitamin K-dependent anticoagulant serine protease in plasma that downregulates the coagulation cascade by degrading cofactors Va and VIIIa by limited proteolysis. ...
Activated protein C (APC) is a vitamin K-dependent anticoagulant serine protease in plasma that downregulates the coagulation cascade …
Electrostatic dependence of the thrombin-thrombomodulin interaction.
Baerga-Ortiz A, Rezaie AR, Komives EA. Baerga-Ortiz A, et al. J Mol Biol. 2000 Feb 18;296(2):651-8. doi: 10.1006/jmbi.1999.3447. J Mol Biol. 2000. PMID: 10669614
The rate constants for the binding interaction between thrombin and a fully active fragment of its anticoagulant cofactor, thrombomodulin, have been determined by surface plasmon resonance. At physiological ionic strength, the k(a) was 6.7x10(6) M(-1) s(-1 )and the dissoci …
The rate constants for the binding interaction between thrombin and a fully active fragment of its anticoagulant cofactor, thrombomodulin, h …
Determinants of specificity of factor xa interaction with its physiological inhibitors.
Rezaie AR. Rezaie AR. Mini Rev Med Chem. 2006 Aug;6(8):859-65. doi: 10.2174/138955706777935017. Mini Rev Med Chem. 2006. PMID: 16918492 Review.
Factor Xa (fXa) is the vitamin K-dependent serine protease of the prothrombinase complex (fXa, factor Va, negatively charged membrane, and calcium) which is responsible for the conversion of prothrombin to thrombin in the final stage of the coagulation cascade. ...
Factor Xa (fXa) is the vitamin K-dependent serine protease of the prothrombinase complex (fXa, factor Va, negatively charged membrane …
The Cardioprotective Signaling Activity of Activated Protein C in Heart Failure and Ischemic Heart Diseases.
Ren D, Giri H, Li J, Rezaie AR. Ren D, et al. Int J Mol Sci. 2019 Apr 10;20(7):1762. doi: 10.3390/ijms20071762. Int J Mol Sci. 2019. PMID: 30974752 Free PMC article. Review.
Activated protein C (APC) is a vitamin-K dependent plasma serine protease, which functions as a natural anticoagulant to downregulate thrombin generation in the clotting cascade. ...
Activated protein C (APC) is a vitamin-K dependent plasma serine protease, which functions as a natural anticoagulant to downregulate …
69 results