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Year Number of Results
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26 results

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Page 1
LSD1 inhibition suppresses ASCL1 and de-represses YAP1 to drive potent activity against neuroendocrine prostate cancer.
Mandl A, Jasmine S, Krueger T, Kumar R, Coleman IM, Dalrymple SL, Antony L, Rosen DM, Jing Y, Hanratty B, Patel RA, Jin-Yih L, Dias J, Celatka CA, Tapper AE, Kleppe M, Kanayama M, Speranzini V, Wang YZ, Luo J, Corey E, Sena LA, Casero RA, Lotan T, Trock BJ, Kachhap SK, Denmeade SR, Carducci MA, Mattevi A, Haffner MC, Nelson PS, Rienhoff HY, Isaacs JT, Brennen WN. Mandl A, et al. Among authors: kachhap sk. bioRxiv [Preprint]. 2024 Jan 22:2024.01.17.576106. doi: 10.1101/2024.01.17.576106. bioRxiv. 2024. PMID: 38328141 Free PMC article. Preprint.
Phase I Trial of Intravenous Mistletoe Extract in Advanced Cancer.
Paller CJ, Wang L, Fu W, Kumar R, Durham JN, Azad NS, Laheru DA, Browner I, Kachhap SK, Boyapati K, Odeny T, Armstrong DK, Meyer CF, Gaillard S, Brahmer JR, Page I, Wang H, Diaz LA Jr. Paller CJ, et al. Among authors: kachhap sk. Cancer Res Commun. 2023 Feb 28;3(2):338-346. doi: 10.1158/2767-9764.CRC-23-0002. eCollection 2023 Feb. Cancer Res Commun. 2023. PMID: 36860652 Free PMC article. Clinical Trial.
Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC.
Sena LA, Kumar R, Sanin DE, Thompson EA, Rosen DM, Dalrymple SL, Antony L, Yang Y, Gomes-Alexandre C, Hicks JL, Jones T, Bowers KA, Eskra JN, Meyers J, Gupta A, Skaist A, Yegnasubramanian S, Luo J, Brennen WN, Kachhap SK, Antonarakis ES, De Marzo AM, Isaacs JT, Markowski MC, Denmeade SR. Sena LA, et al. Among authors: kachhap sk. J Clin Invest. 2022 Dec 1;132(23):e162396. doi: 10.1172/JCI162396. J Clin Invest. 2022. PMID: 36194476 Free PMC article.
Supraphysiologic Testosterone Induces Ferroptosis and Activates Immune Pathways through Nucleophagy in Prostate Cancer.
Kumar R, Mendonca J, Owoyemi O, Boyapati K, Thomas N, Kanacharoen S, Coffey M, Topiwala D, Gomes C, Ozbek B, Jones T, Rosen M, Dong L, Wiens S, Brennen WN, Isaacs JT, De Marzo AM, Markowski MC, Antonarakis ES, Qian DZ, Pienta KJ, Pardoll DM, Carducci MA, Denmeade SR, Kachhap SK. Kumar R, et al. Among authors: kachhap sk. Cancer Res. 2021 Dec 1;81(23):5948-5962. doi: 10.1158/0008-5472.CAN-20-3607. Epub 2021 Oct 13. Cancer Res. 2021. PMID: 34645612 Free PMC article.
HIF1 and ID1 Interplay Confers Adaptive Survival to HIF1α-Inhibition.
Geng H, Ko HK, Pittsenbarger J, Harvey CT, Xue C, Liu Q, Wiens S, Kachhap SK, Beer TM, Qian DZ. Geng H, et al. Among authors: kachhap sk. Front Cell Dev Biol. 2021 Nov 8;9:724059. doi: 10.3389/fcell.2021.724059. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34820369 Free PMC article.
CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor.
Kumar R, Mendonca J, Shetty A, Yang Y, Owoyemi O, Wilson L, Boyapati K, Topiwala D, Thomas N, Nguyen H, Luo J, Paller CJ, Denmeade S, Carducci MA, Kachhap SK. Kumar R, et al. Among authors: kachhap sk. bioRxiv [Preprint]. 2024 Feb 16:2024.02.13.579966. doi: 10.1101/2024.02.13.579966. bioRxiv. 2024. Update in: FASEB J. 2025 Jan 31;39(2):e70342. doi: 10.1096/fj.202400490R. PMID: 38405771 Free PMC article. Updated. Preprint.
Muscadine grape skin extract inhibits prostate cancer cells by inducing cell-cycle arrest, and decreasing migration through heat shock protein 40.
Ignacio DN, Mason KD, Hackett-Morton EC, Albanese C, Ringer L, Wagner WD, Wang PC, Carducci MA, Kachhap SK, Paller CJ, Mendonca J, Li-Ying Chan L, Lin B, Hartle DK, Green JE, Brown CA, Hudson TS. Ignacio DN, et al. Among authors: kachhap sk. Heliyon. 2019 Jan 16;5(1):e01128. doi: 10.1016/j.heliyon.2019.e01128. eCollection 2019 Jan. Heliyon. 2019. PMID: 30705983 Free PMC article.
26 results