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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1994 2
1995 1
1996 2
1997 1
1998 3
1999 3
2000 2
2001 3
2002 3
2003 6
2004 5
2005 5
2006 6
2007 6
2008 5
2009 9
2010 7
2011 12
2012 11
2013 11
2014 8
2015 9
2016 10
2017 9
2018 8
2019 4
2020 8
2021 5
2022 12
2023 0
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157 results
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Page 1
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Owen DR, Allerton CMN, Anderson AS, Aschenbrenner L, Avery M, Berritt S, Boras B, Cardin RD, Carlo A, Coffman KJ, Dantonio A, Di L, Eng H, Ferre R, Gajiwala KS, Gibson SA, Greasley SE, Hurst BL, Kadar EP, Kalgutkar AS, Lee JC, Lee J, Liu W, Mason SW, Noell S, Novak JJ, Obach RS, Ogilvie K, Patel NC, Pettersson M, Rai DK, Reese MR, Sammons MF, Sathish JG, Singh RSP, Steppan CM, Stewart AE, Tuttle JB, Updyke L, Verhoest PR, Wei L, Yang Q, Zhu Y. Owen DR, et al. Among authors: kalgutkar as. Science. 2021 Dec 24;374(6575):1586-1593. doi: 10.1126/science.abl4784. Epub 2021 Nov 2. Science. 2021. PMID: 34726479 Free article.
A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
Griffith DA, Edmonds DJ, Fortin JP, Kalgutkar AS, Kuzmiski JB, Loria PM, Saxena AR, Bagley SW, Buckeridge C, Curto JM, Derksen DR, Dias JM, Griffor MC, Han S, Jackson VM, Landis MS, Lettiere D, Limberakis C, Liu Y, Mathiowetz AM, Patel JC, Piotrowski DW, Price DA, Ruggeri RB, Tess DA. Griffith DA, et al. Among authors: kalgutkar as. J Med Chem. 2022 Jun 23;65(12):8208-8226. doi: 10.1021/acs.jmedchem.1c01856. Epub 2022 Jun 1. J Med Chem. 2022. PMID: 35647711 Free PMC article.
Comprehensive Nonclinical Safety Assessment of Nirmatrelvir Supporting Timely Development of the SARS-COV-2 Antiviral Therapeutic, Paxlovid™.
Sathish JG, Bhatt S, DaSilva JK, Flynn D, Jenkinson S, Kalgutkar AS, Liu M, Manickam B, Pinkstaff J, Reagan WJ, Shirai N, Shoieb AM, Sirivelu M, Vispute S, Vitsky A, Walters K, Wisialowski TA, Updyke LW. Sathish JG, et al. Among authors: kalgutkar as. Int J Toxicol. 2022 Aug;41(4):276-290. doi: 10.1177/10915818221095489. Epub 2022 May 21. Int J Toxicol. 2022. PMID: 35603517 Free PMC article.
Biotransformation novel advances - 2021 year in review.
Khojasteh SC, Argikar UA, Cho S, Crouch R, Heck CJS, Johnson KM, Kalgutkar AS, King L, Maw HH, Seneviratne HK, Wang S, Wei C, Zhang D, Jackson KD. Khojasteh SC, et al. Among authors: kalgutkar as. Drug Metab Rev. 2022 Aug;54(3):207-245. doi: 10.1080/03602532.2022.2097253. Epub 2022 Aug 30. Drug Metab Rev. 2022. PMID: 35815654 Review.
Metabolic activation in drug-induced liver injury.
Leung L, Kalgutkar AS, Obach RS. Leung L, et al. Among authors: kalgutkar as. Drug Metab Rev. 2012 Feb;44(1):18-33. doi: 10.3109/03602532.2011.605791. Epub 2011 Sep 23. Drug Metab Rev. 2012. PMID: 21939431 Review.
157 results