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Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research.
Casas B, Vilén L, Bauer S, Kanebratt KP, Wennberg Huldt C, Magnusson L, Marx U, Andersson TB, Gennemark P, Cedersund G. Casas B, et al. Among authors: kanebratt kp. PLoS Comput Biol. 2022 Oct 19;18(10):e1010587. doi: 10.1371/journal.pcbi.1010587. eCollection 2022 Oct. PLoS Comput Biol. 2022. PMID: 36260620 Free PMC article.
The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids.
Prill S, Caddeo A, Baselli G, Jamialahmadi O, Dongiovanni P, Rametta R, Kanebratt KP, Pujia A, Pingitore P, Mancina RM, Lindén D, Whatling C, Janefeldt A, Kozyra M, Ingelman-Sundberg M, Valenti L, Andersson TB, Romeo S. Prill S, et al. Among authors: kanebratt kp. Sci Rep. 2019 Aug 12;9(1):11585. doi: 10.1038/s41598-019-47737-w. Sci Rep. 2019. PMID: 31406127 Free PMC article.
Publisher Correction: Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model.
Bauer S, Wennberg Huldt C, Kanebratt KP, Durieux I, Gunne D, Andersson S, Ewart L, Haynes WG, Maschmeyer I, Winter A, Ämmälä C, Marx U, Andersson TB. Bauer S, et al. Among authors: kanebratt kp. Sci Rep. 2018 Jan 23;8(1):1672. doi: 10.1038/s41598-018-20340-1. Sci Rep. 2018. PMID: 29362490 Free PMC article.
Critical differences in drug metabolic properties of human hepatic cellular models, including primary human hepatocytes, stem cell derived hepatocytes, and hepatoma cell lines.
Kvist AJ, Kanebratt KP, Walentinsson A, Palmgren H, O'Hara M, Björkbom A, Andersson LC, Ahlqvist M, Andersson TB. Kvist AJ, et al. Among authors: kanebratt kp. Biochem Pharmacol. 2018 Sep;155:124-140. doi: 10.1016/j.bcp.2018.06.026. Epub 2018 Jun 25. Biochem Pharmacol. 2018. PMID: 29953844
16 results