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Ubiquitin regulates GGA3-mediated degradation of BACE1.
Kang EL, Cameron AN, Piazza F, Walker KR, Tesco G. Kang EL, et al. J Biol Chem. 2010 Jul 30;285(31):24108-19. doi: 10.1074/jbc.M109.092742. Epub 2010 May 18. J Biol Chem. 2010. PMID: 20484053 Free PMC article.
Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity.
Tesco G, Koh YH, Kang EL, Cameron AN, Das S, Sena-Esteves M, Hiltunen M, Yang SH, Zhong Z, Shen Y, Simpkins JW, Tanzi RE. Tesco G, et al. Among authors: kang el. Neuron. 2007 Jun 7;54(5):721-37. doi: 10.1016/j.neuron.2007.05.012. Neuron. 2007. PMID: 17553422 Free PMC article.