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Page 1
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases.
Sturm G, Karan KR, Monzel AS, Santhanam B, Taivassalo T, Bris C, Ware SA, Cross M, Towheed A, Higgins-Chen A, McManus MJ, Cardenas A, Lin J, Epel ES, Rahman S, Vissing J, Grassi B, Levine M, Horvath S, Haller RG, Lenaers G, Wallace DC, St-Onge MP, Tavazoie S, Procaccio V, Kaufman BA, Seifert EL, Hirano M, Picard M. Sturm G, et al. Among authors: karan kr. Commun Biol. 2023 Jan 12;6(1):22. doi: 10.1038/s42003-022-04303-x. Commun Biol. 2023. PMID: 36635485 Free PMC article.
Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging.
Bobba-Alves N, Sturm G, Lin J, Ware SA, Karan KR, Monzel AS, Bris C, Procaccio V, Lenaers G, Higgins-Chen A, Levine M, Horvath S, Santhanam BS, Kaufman BA, Hirano M, Epel E, Picard M. Bobba-Alves N, et al. Among authors: karan kr. Psychoneuroendocrinology. 2023 Sep;155:106322. doi: 10.1016/j.psyneuen.2023.106322. Epub 2023 Jun 14. Psychoneuroendocrinology. 2023. PMID: 37423094 Free PMC article.
Stress and circulating cell-free mitochondrial DNA: A systematic review of human studies, physiological considerations, and technical recommendations.
Trumpff C, Michelson J, Lagranha CJ, Taleon V, Karan KR, Sturm G, Lindqvist D, Fernström J, Moser D, Kaufman BA, Picard M. Trumpff C, et al. Among authors: karan kr. Mitochondrion. 2021 Jul;59:225-245. doi: 10.1016/j.mito.2021.04.002. Epub 2021 Apr 9. Mitochondrion. 2021. PMID: 33839318 Free PMC article. Review.
Rare SLC1A1 variants in hot water epilepsy.
Karan KR, Satishchandra P, Sinha S, Anand A. Karan KR, et al. Hum Genet. 2017 Jun;136(6):693-703. doi: 10.1007/s00439-017-1778-7. Epub 2017 Mar 21. Hum Genet. 2017. PMID: 28324217
Dynamic behavior of cell-free mitochondrial DNA in human saliva.
Trumpff C, Rausser S, Haahr R, Karan KR, Gouspillou G, Puterman E, Kirschbaum C, Picard M. Trumpff C, et al. Among authors: karan kr. Psychoneuroendocrinology. 2022 Sep;143:105852. doi: 10.1016/j.psyneuen.2022.105852. Epub 2022 Jun 30. Psychoneuroendocrinology. 2022. PMID: 35834882 Free PMC article.
13 results