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Moderate intensity aerobic exercise alleviates motor deficits in 6-OHDA lesioned rats and reduces serum levels of biomarkers of Parkinson's disease severity without recovery of striatal dopamine or tyrosine hydroxylase.
Kasanga EA, Soto I, Centner A, McManus R, Shifflet MK, Navarrete W, Han Y, Lisk J, Ehrhardt T, Wheeler K, Mhatre-Winters I, Richardson JR, Bishop C, Nejtek VA, Salvatore MF. Kasanga EA, et al. Exp Neurol. 2024 Sep;379:114875. doi: 10.1016/j.expneurol.2024.114875. Epub 2024 Jun 27. Exp Neurol. 2024. PMID: 38944332 Free article.
Aging-related limit of exercise efficacy on motor decline.
Arnold JC, Cantu MA, Kasanga EA, Nejtek VA, Papa EV, Bugnariu N, Salvatore MF. Arnold JC, et al. Among authors: kasanga ea. PLoS One. 2017 Nov 27;12(11):e0188538. doi: 10.1371/journal.pone.0188538. eCollection 2017. PLoS One. 2017. PMID: 29176896 Free PMC article.
Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs.
Kasanga EA, Han Y, Shifflet MK, Navarrete W, McManus R, Parry C, Barahona A, Nejtek VA, Manfredsson FP, Kordower JH, Richardson JR, Salvatore MF. Kasanga EA, et al. Exp Neurol. 2023 Oct;368:114509. doi: 10.1016/j.expneurol.2023.114509. Epub 2023 Aug 25. Exp Neurol. 2023. PMID: 37634696
Modulation of nigral dopamine signaling mitigates parkinsonian signs of aging: evidence from intervention with calorie restriction or inhibition of dopamine uptake.
Salvatore MF, Kasanga EA, Kelley DP, Venable KE, McInnis TR, Cantu MA, Terrebonne J, Lanza K, Meadows SM, Centner A, Bishop C, Ingram DK. Salvatore MF, et al. Among authors: kasanga ea. Geroscience. 2023 Feb;45(1):45-63. doi: 10.1007/s11357-022-00583-7. Epub 2022 May 30. Geroscience. 2023. PMID: 35635679 Free PMC article.
Moderate intensity aerobic exercise in 6-OHDA-lesioned rats alleviates established motor deficits and reduces neurofilament light and glial fibrillary acidic protein serum levels without increased striatal dopamine or tyrosine hydroxylase protein.
Kasanga EA, Soto I, Centner A, McManus R, Shifflet MK, Navarrete W, Han Y, Lisk J, Wheeler K, Mhatre-Winters I, Richardson JR, Bishop C, Nejtek VA, Salvatore MF. Kasanga EA, et al. bioRxiv [Preprint]. 2023 Jul 12:2023.07.11.548638. doi: 10.1101/2023.07.11.548638. bioRxiv. 2023. Update in: Exp Neurol. 2024 Sep;379:114875. doi: 10.1016/j.expneurol.2024.114875 PMID: 37502851 Free PMC article. Updated. Preprint.
19 results