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2019 1
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2021 6
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Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease.
Rathnayake AD, Kim Y, Dampalla CS, Nguyen HN, Jesri AM, Kashipathy MM, Lushington GH, Battaile KP, Lovell S, Chang KO, Groutas WC. Rathnayake AD, et al. Among authors: kashipathy mm. J Med Chem. 2020 Oct 22;63(20):11945-11963. doi: 10.1021/acs.jmedchem.0c01252. Epub 2020 Oct 2. J Med Chem. 2020. PMID: 32945669
The SARS-CoV-2 conserved macrodomain is a highly efficient ADP-ribosylhydrolase enzyme.
Alhammad YMO, Kashipathy MM, Roy A, Gagné JP, McDonald P, Gao P, Nonfoux L, Battaile KP, Johnson DK, Holmstrom ED, Poirier GG, Lovell S, Fehr AR. Alhammad YMO, et al. Among authors: kashipathy mm. bioRxiv. 2020 May 12:2020.05.11.089375. doi: 10.1101/2020.05.11.089375. Preprint. bioRxiv. 2020. PMID: 32511412 Free PMC article. Updated.
The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase.
Alhammad YMO, Kashipathy MM, Roy A, Gagné JP, McDonald P, Gao P, Nonfoux L, Battaile KP, Johnson DK, Holmstrom ED, Poirier GG, Lovell S, Fehr AR. Alhammad YMO, et al. Among authors: kashipathy mm. J Virol. 2021 Jan 13;95(3):e01969-20. doi: 10.1128/JVI.01969-20. Print 2021 Jan 13. J Virol. 2021. PMID: 33158944 Free PMC article.
Costameric integrin and sarcoglycan protein levels are altered in a Drosophila model for Limb-girdle muscular dystrophy type 2H.
Bawa S, Gameros S, Baumann K, Brooks DS, Kollhoff JA, Zolkiewski M, Re Cecconi AD, Panini N, Russo M, Piccirillo R, Johnson DK, Kashipathy MM, Battaile KP, Lovell S, Bouyain SEA, Kawakami J, Geisbrecht ER. Bawa S, et al. Among authors: kashipathy mm. Mol Biol Cell. 2021 Feb 1;32(3):260-273. doi: 10.1091/mbc.E20-07-0453. Epub 2020 Dec 9. Mol Biol Cell. 2021. PMID: 33296226 Free PMC article.
Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases.
Wiedmann M, Dranchak PK, Aitha M, Queme B, Collmus CD, Kashipathy MM, Kanter L, Lamy L, Rogers JM, Tao D, Battaile KP, Rai G, Lovell S, Suga H, Inglese J. Wiedmann M, et al. Among authors: kashipathy mm. J Biol Chem. 2021 Jan-Jun;296:100628. doi: 10.1016/j.jbc.2021.100628. Epub 2021 Apr 1. J Biol Chem. 2021. PMID: 33812994 Free PMC article.
Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease.
Dampalla CS, Kim Y, Bickmeier N, Rathnayake AD, Nguyen HN, Zheng J, Kashipathy MM, Baird MA, Battaile KP, Lovell S, Perlman S, Chang KO, Groutas WC. Dampalla CS, et al. Among authors: kashipathy mm. J Med Chem. 2021 Jul 22;64(14):10047-10058. doi: 10.1021/acs.jmedchem.1c00319. Epub 2021 Jul 2. J Med Chem. 2021. PMID: 34213885 Free PMC article.
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