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Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey.
Ward KW, Stelman GJ, Morgan JA, Zeigler KS, Azzarano LM, Kehler JR, McSurdy-Freed JE, Proksch JW, Smith BR. Ward KW, et al. Among authors: kehler jr. Drug Metab Dispos. 2004 Feb;32(2):172-7. doi: 10.1124/dmd.32.2.172. Drug Metab Dispos. 2004. PMID: 14744938