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Targeted degradation via direct 26S proteasome recruitment.
Bashore C, Prakash S, Johnson MC, Conrad RJ, Kekessie IA, Scales SJ, Ishisoko N, Kleinheinz T, Liu PS, Popovych N, Wecksler AT, Zhou L, Tam C, Zilberleyb I, Srinivasan R, Blake RA, Song A, Staben ST, Zhang Y, Arnott D, Fairbrother WJ, Foster SA, Wertz IE, Ciferri C, Dueber EC. Bashore C, et al. Among authors: kekessie ia. Nat Chem Biol. 2023 Jan;19(1):55-63. doi: 10.1038/s41589-022-01218-w. Epub 2022 Dec 28. Nat Chem Biol. 2023. PMID: 36577875 Free PMC article.
Liposomal Permeation Assay for Droplet-Scale Pharmacokinetic Screening.
Hu J, Chan AI, Adaligil E, Kekessie I, Takahashi M, Song A, Cunningham CN, Paegel BM. Hu J, et al. Among authors: kekessie i. J Med Chem. 2023 May 11;66(9):6288-6296. doi: 10.1021/acs.jmedchem.3c00138. Epub 2023 Apr 19. J Med Chem. 2023. PMID: 37075027 Free PMC article.