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Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s.

Oba T, Long MD, Keler T, Marsh HC, Minderman H, Abrams SI, Liu S, Ito F. Oba T, et al. Among authors: keler t. Nat Commun. 2020 Oct 27;11(1):5415. doi: 10.1038/s41467-020-19192-z. Nat Commun. 2020. PMID: 33110069 Free PMC article.

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High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.

Alcántara-Hernández M, Leylek R, Wagar LE, Engleman EG, Keler T, Marinkovich MP, Davis MM, Nolan GP, Idoyaga J. Alcántara-Hernández M, et al. Among authors: keler t. Immunity. 2017 Dec 19;47(6):1037-1050.e6. doi: 10.1016/j.immuni.2017.11.001. Epub 2017 Dec 5. Immunity. 2017. PMID: 29221729 Free PMC article.

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Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial.

Weller M, Butowski N, Tran DD, Recht LD, Lim M, Hirte H, Ashby L, Mechtler L, Goldlust SA, Iwamoto F, Drappatz J, O'Rourke DM, Wong M, Hamilton MG, Finocchiaro G, Perry J, Wick W, Green J, He Y, Turner CD, Yellin MJ, Keler T, Davis TA, Stupp R, Sampson JH; ACT IV trial investigators. Weller M, et al. Among authors: keler t. Lancet Oncol. 2017 Oct;18(10):1373-1385. doi: 10.1016/S1470-2045(17)30517-X. Epub 2017 Aug 23. Lancet Oncol. 2017. PMID: 28844499 Free article. Clinical Trial.

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Antibody-targeted vaccines.

Keler T, He L, Ramakrishna V, Champion B. Keler T, et al. Oncogene. 2007 May 28;26(25):3758-67. doi: 10.1038/sj.onc.1210375. Oncogene. 2007. PMID: 17530028 Review.

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Mannose receptor-targeted vaccines.

Keler T, Ramakrishna V, Fanger MW. Keler T, et al. Expert Opin Biol Ther. 2004 Dec;4(12):1953-62. doi: 10.1517/14712598.4.12.1953. Expert Opin Biol Ther. 2004. PMID: 15571457 Review.

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Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity.

Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ, Steinman RM. Trumpfheller C, et al. Among authors: keler t. J Intern Med. 2012 Feb;271(2):183-92. doi: 10.1111/j.1365-2796.2011.02496.x. Epub 2012 Jan 4. J Intern Med. 2012. PMID: 22126373 Free PMC article. Review.

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Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy.

Vitale LA, Thomas LJ, He LZ, O'Neill T, Widger J, Crocker A, Sundarapandiyan K, Storey JR, Forsberg EM, Weidlick J, Baronas AR, Gergel LE, Boyer JM, Sisson C, Goldstein J, Marsh HC Jr, Keler T. Vitale LA, et al. Among authors: keler t. Cancer Immunol Immunother. 2019 Feb;68(2):233-245. doi: 10.1007/s00262-018-2267-0. Epub 2018 Oct 31. Cancer Immunol Immunother. 2019. PMID: 30382327

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A Critical Role of CD40 and CD70 Signaling in Conventional Type 1 Dendritic Cells in Expansion and Antitumor Efficacy of Adoptively Transferred Tumor-Specific T Cells.

Oba T, Hoki T, Yamauchi T, Keler T, Marsh HC, Cao X, Ito F. Oba T, et al. Among authors: keler t. J Immunol. 2020 Oct 1;205(7):1867-1877. doi: 10.4049/jimmunol.2000347. Epub 2020 Aug 26. J Immunol. 2020. PMID: 32848036 Free PMC article.

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CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer.

Morse MA, Bradley DA, Keler T, Laliberte RJ, Green JA, Davis TA, Inman BA. Morse MA, et al. Among authors: keler t. Expert Rev Vaccines. 2011 Jun;10(6):733-42. doi: 10.1586/erv.11.20. Expert Rev Vaccines. 2011. PMID: 21692696 Review.

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Conventional Dendritic Cells Impair Recovery after Myocardial Infarction.

Lee JS, Jeong SJ, Kim S, Chalifour L, Yun TJ, Miah MA, Li B, Majdoubi A, Sabourin A, Keler T, Guimond JV, Haddad E, Choi EY, Epelman S, Choi JH, Thibodeau J, Oh GT, Cheong C. Lee JS, et al. Among authors: keler t. J Immunol. 2018 Sep 15;201(6):1784-1798. doi: 10.4049/jimmunol.1800322. Epub 2018 Aug 10. J Immunol. 2018. PMID: 30097529 Free article.

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