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Year Number of Results
1947 1
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1988 5
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1995 5
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2006 17
2007 11
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2009 9
2010 16
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485 results

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Page 1
KERA: analysis tool for multi-process, multi-state single-molecule data.
Tibbs J, Ghoneim M, Caldwell CC, Buzynski T, Bowie W, Boehm EM, Washington MT, Tabei SMA, Spies M. Tibbs J, et al. Nucleic Acids Res. 2021 May 21;49(9):e53. doi: 10.1093/nar/gkab087. Nucleic Acids Res. 2021. PMID: 33660771 Free PMC article.
Here, we describe the kinetic event resolving algorithm (KERA), a software tool for organizing and sorting the discretized fluorescent trajectories from a range of single-molecule experiments. KERA organizes the data in groups by transition patterns, and displays ex …
Here, we describe the kinetic event resolving algorithm (KERA), a software tool for organizing and sorting the discretized fluorescen …
Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial.
Khanani AM, Patel SS, Staurenghi G, Tadayoni R, Danzig CJ, Eichenbaum DA, Hsu J, Wykoff CC, Heier JS, Lally DR, Monés J, Nielsen JS, Sheth VS, Kaiser PK, Clark J, Zhu L, Patel H, Tang J, Desai D, Jaffe GJ; GATHER2 trial investigators. Khanani AM, et al. Lancet. 2023 Oct 21;402(10411):1449-1458. doi: 10.1016/S0140-6736(23)01583-0. Epub 2023 Sep 8. Lancet. 2023. PMID: 37696275
A Novel KERA Mutation in a Case of Autosomal Recessive Cornea Plana With Primary Angle-Closure Glaucoma.
Kumari D, Tiwari A, Choudhury M, Kumar A, Rao A, Dixit M. Kumari D, et al. J Glaucoma. 2016 Feb;25(2):e106-9. doi: 10.1097/IJG.0000000000000258. J Glaucoma. 2016. PMID: 25967529
In human beings, mutations in keratocan (KERA) are associated with autosomal recessive cornea plana (CNA2), which is characterized by a flattened forward convex curvature of the cornea. Here, we report a novel mutation in a case of autosomal recessive bilateral cornea plan …
In human beings, mutations in keratocan (KERA) are associated with autosomal recessive cornea plana (CNA2), which is characterized by …
Tissue-specific functions of MSCs are linked to homeostatic muscle maintenance and alter with aging.
Kurosawa T, Ikemoto-Uezumi M, Yoshimoto Y, Minato K, Kaji N, Chaen T, Hase E, Minamikawa T, Yasui T, Horiguchi K, Iino S, Hori M, Uezumi A. Kurosawa T, et al. Aging Cell. 2024 Nov;23(11):e14299. doi: 10.1111/acel.14299. Epub 2024 Sep 25. Aging Cell. 2024. PMID: 39323233 Free PMC article.
By first analyzing age-related changes, we found that Kera is exclusively expressed in muscle MSCs and significantly down-regulated by aging. Kera knockout mice recapitulated some sarcopenic phenotypes including reduced muscle mass and specific force, revealing the …
By first analyzing age-related changes, we found that Kera is exclusively expressed in muscle MSCs and significantly down-regulated b …
Authors' response.
Fujijyama K, Kera Y, Yujin S, Tanikawa C, Yamashiro T, Guo X, Ni A, Deguchi T. Fujijyama K, et al. Am J Orthod Dentofacial Orthop. 2023 Jan;163(1):2-3. doi: 10.1016/j.ajodo.2022.05.017. Am J Orthod Dentofacial Orthop. 2023. PMID: 36549831 No abstract available.
Transforming growth factor beta receptor 2 (Tgfbr2) deficiency in keratocytes results in corneal ectasia.
Wang YC, Zolnik OB, Yasoda S, Yeh LK, Yuan Y, Kao W, Saika S, Liu CY. Wang YC, et al. Ocul Surf. 2023 Jul;29:557-565. doi: 10.1016/j.jtos.2023.06.014. Epub 2023 Jun 30. Ocul Surf. 2023. PMID: 37393064
RESULTS: Slit-Lamp revealed that corneas were transparent in both Tgfbr2(kera-cko) and Tgfbr2(Ctrl), however, Tgfbr2(kera-cko) cornea was 33.5% and 42.9% thinner as compared with those of Tgfbr2(Ctrl) at P42 and P70, respectively. H&E and semithin section staini …
RESULTS: Slit-Lamp revealed that corneas were transparent in both Tgfbr2(kera-cko) and Tgfbr2(Ctrl), however, Tgfbr2(kera-cko) …
SMAD4-Dependent Signaling Pathway Involves in the Pathogenesis of TGFBR2-Related CE-like Phenotype.
Wang YC, Zolnik OB, Liu CY. Wang YC, et al. Cells. 2024 Apr 4;13(7):626. doi: 10.3390/cells13070626. Cells. 2024. PMID: 38607065 Free PMC article.
Furthermore, the measurements of the Anterior Chamber and Corneal Radius indicated a substantial ectatic cornea in the Smad4(kera-cko) compared to Smad4(Ctrl). The H&E staining of Smad4(kera-cko) mimics the finding in the Tgfbr2(kera-cko). ...Both immunos …
Furthermore, the measurements of the Anterior Chamber and Corneal Radius indicated a substantial ectatic cornea in the Smad4(kera-cko …
Mutation in KERA identified by linkage analysis and targeted resequencing in a pedigree with premature atherosclerosis.
Maiwald S, Sivapalaratnam S, Motazacker MM, van Capelleveen JC, Bot I, de Jager SC, van Eck M, Jolley J, Kuiper J, Stephens J, Albers CA, Vosmeer CR, Kruize H, Geerke DP, van der Wal AC, van der Loos CM, Kastelein JJ, Trip MD, Ouwehand WH, Dallinga-Thie GM, Hovingh GK. Maiwald S, et al. PLoS One. 2014 May 30;9(5):e98289. doi: 10.1371/journal.pone.0098289. eCollection 2014. PLoS One. 2014. PMID: 24879339 Free PMC article.
KERA, a proteoglycan protein, was expressed in lipid-rich areas of human atherosclerotic lesions, but not in healthy arterial specimens. ...CONCLUSION: A rare variant in KERA was identified in a large kindred with premature atherosclerosis. The identification of …
KERA, a proteoglycan protein, was expressed in lipid-rich areas of human atherosclerotic lesions, but not in healthy arterial specime …
A novel KERA mutation associated with autosomal recessive cornea plana.
Khan A, Al-Saif A, Kambouris M. Khan A, et al. Ophthalmic Genet. 2004 Jun;25(2):147-52. doi: 10.1080/13816810490514397. Ophthalmic Genet. 2004. PMID: 15370545
PURPOSE: To report a novel KERA mutation associated with autosomal recessive cornea plana in members of a nuclear family and to describe their ophthalmic phenotypes. ...CONCLUSIONS: This novel point mutation in KERA is the fourth thus far described. The ocular pheno …
PURPOSE: To report a novel KERA mutation associated with autosomal recessive cornea plana in members of a nuclear family and to descr …
485 results