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Year Number of Results
2002 2
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2006 1
2007 3
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2009 4
2010 5
2011 5
2012 9
2013 7
2014 9
2015 6
2016 1
2017 3
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2019 7
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89 results

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Page 1
Acquired Resistance to KRASG12C Inhibition in Cancer.
Awad MM, Liu S, Rybkin II, Arbour KC, Dilly J, Zhu VW, Johnson ML, Heist RS, Patil T, Riely GJ, Jacobson JO, Yang X, Persky NS, Root DE, Lowder KE, Feng H, Zhang SS, Haigis KM, Hung YP, Sholl LM, Wolpin BM, Wiese J, Christiansen J, Lee J, Schrock AB, Lim LP, Garg K, Li M, Engstrom LD, Waters L, Lawson JD, Olson P, Lito P, Ou SI, Christensen JG, Jänne PA, Aguirre AJ. Awad MM, et al. Among authors: haigis km. N Engl J Med. 2021 Jun 24;384(25):2382-2393. doi: 10.1056/NEJMoa2105281. N Engl J Med. 2021. PMID: 34161704 Free PMC article.
Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers.
Loi P, Schade AE, Rodriguez CL, Krishnan A, Perurena N, Nguyen VTM, Xu Y, Watanabe M, Davis RA, Gardner A, Pilla NF, Mattioli K, Popow O, Gunduz N, Lannagan TRM, Fitzgerald S, Sicinska ET, Lin JR, Tan W, Brais LK, Haigis KM, Giannakis M, Ng K, Santagata S, Helin K, Sansom OJ, Cichowski K. Loi P, et al. Among authors: haigis km. Cancer Discov. 2024 Dec 2;14(12):2430-2449. doi: 10.1158/2159-8290.CD-23-0866. Cancer Discov. 2024. PMID: 39121480 Free PMC article.
GUK1 activation is a metabolic liability in lung cancer.
Schneider JL, Kurmi K, Dai Y, Dhiman I, Joshi S, Gassaway BM, Johnson CW, Jones N, Li Z, Joschko CP, Fujino T, Paulo JA, Yoda S, Baquer G, Ruiz D, Stopka SA, Kelley L, Do A, Mino-Kenudson M, Sequist LV, Lin JJ, Agar NYR, Gygi SP, Haigis KM, Hata AN, Haigis MC. Schneider JL, et al. Among authors: haigis km. Cell. 2025 Mar 6;188(5):1248-1264.e23. doi: 10.1016/j.cell.2025.01.024. Epub 2025 Feb 6. Cell. 2025. PMID: 39919745 Free PMC article.
Oncogenic K-Ras suppresses global miRNA function.
Shui B, Beyett TS, Chen Z, Li X, La Rocca G, Gazlay WM, Eck MJ, Lau KS, Ventura A, Haigis KM. Shui B, et al. Among authors: haigis km. Mol Cell. 2023 Jul 20;83(14):2509-2523.e13. doi: 10.1016/j.molcel.2023.06.008. Epub 2023 Jul 3. Mol Cell. 2023. PMID: 37402366 Free PMC article.
Interplay between K-RAS and miRNAs.
Shui B, La Rocca G, Ventura A, Haigis KM. Shui B, et al. Among authors: haigis km. Trends Cancer. 2022 May;8(5):384-396. doi: 10.1016/j.trecan.2022.01.002. Epub 2022 Jan 31. Trends Cancer. 2022. PMID: 35093302 Free PMC article. Review.
Comprehensive structure-function analysis reveals gain- and loss-of-function mechanisms impacting oncogenic KRAS activity.
Kwon JJ, Dilly J, Liu S, Kim E, Bian Y, Dharmaiah S, Tran TH, Kapner KS, Ly SH, Yang X, Rabara D, Waybright TJ, Giacomelli AO, Hong AL, Misek S, Wang B, Ravi A, Doench JG, Beroukhim R, Lemke CT, Haigis KM, Esposito D, Root DE, Nissley DV, Stephen AG, McCormick F, Simanshu DK, Hahn WC, Aguirre AJ. Kwon JJ, et al. Among authors: haigis km. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.618529. doi: 10.1101/2024.10.22.618529. bioRxiv. 2024. PMID: 39484452 Free PMC article. Preprint.
KRAS Alleles: The Devil Is in the Detail.
Haigis KM. Haigis KM. Trends Cancer. 2017 Oct;3(10):686-697. doi: 10.1016/j.trecan.2017.08.006. Epub 2017 Sep 12. Trends Cancer. 2017. PMID: 28958387 Free PMC article. Review.
89 results