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Reduced vitamin K status as a potentially modifiable risk factor of severe COVID-19.

Dofferhoff ASM, Piscaer I, Schurgers LJ, Visser MPJ, van den Ouweland JMW, de Jong PA, Gosens R, Hackeng TM, van Daal H, Lux P, Maassen C, Karssemeijer EGA, Vermeer C, Wouters EFM, Kistemaker LEM, Walk J, Janssen R. Dofferhoff ASM, et al. Among authors: kistemaker lem. Clin Infect Dis. 2020 Aug 27:ciaa1258. doi: 10.1093/cid/ciaa1258. Online ahead of print. Clin Infect Dis. 2020. PMID: 32852539 Free PMC article.

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Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors.

Wu X, van Dijk EM, Ng-Blichfeldt JP, Bos IST, Ciminieri C, Königshoff M, Kistemaker LEM, Gosens R. Wu X, et al. Among authors: kistemaker lem. Cells. 2019 Sep 25;8(10):1147. doi: 10.3390/cells8101147. Cells. 2019. PMID: 31557955 Free PMC article.

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Airway Innervation and Plasticity in Asthma.

Kistemaker LEM, Prakash YS. Kistemaker LEM, et al. Physiology (Bethesda). 2019 Jul 1;34(4):283-298. doi: 10.1152/physiol.00050.2018. Physiology (Bethesda). 2019. PMID: 31165683 Free PMC article. Review.

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Mouse Lung Tissue Slice Culture.

Wu X, van Dijk EM, Bos IST, Kistemaker LEM, Gosens R. Wu X, et al. Among authors: kistemaker lem. Methods Mol Biol. 2019;1940:297-311. doi: 10.1007/978-1-4939-9086-3_21. Methods Mol Biol. 2019. PMID: 30788834

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Cholinergic neuroplasticity in asthma driven by TrkB signaling.

Dragunas G, Woest ME, Nijboer S, Bos ST, van Asselt J, de Groot AP, Vohlídalová E, Vermeulen CJ, Ditz B, Vonk JM, Koppelman GH, van den Berge M, Ten Hacken NHT, Timens W, Munhoz CD, Prakash YS, Gosens R, Kistemaker LEM. Dragunas G, et al. Among authors: kistemaker lem. FASEB J. 2020 Jun;34(6):7703-7717. doi: 10.1096/fj.202000170R. Epub 2020 Apr 11. FASEB J. 2020. PMID: 32277855 Free PMC article.

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Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling.

Kistemaker LE, Gosens R. Kistemaker LE, et al. Trends Pharmacol Sci. 2015 Mar;36(3):164-71. doi: 10.1016/j.tips.2014.11.005. Epub 2014 Dec 13. Trends Pharmacol Sci. 2015. PMID: 25511176 Review.

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A new perspective on muscarinic receptor antagonism in obstructive airways diseases.

Meurs H, Oenema TA, Kistemaker LE, Gosens R. Meurs H, et al. Among authors: kistemaker le. Curr Opin Pharmacol. 2013 Jun;13(3):316-23. doi: 10.1016/j.coph.2013.04.004. Epub 2013 May 3. Curr Opin Pharmacol. 2013. PMID: 23643733 Review.

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Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling.

Noble PB, Pascoe CD, Lan B, Ito S, Kistemaker LE, Tatler AL, Pera T, Brook BS, Gosens R, West AR. Noble PB, et al. Among authors: kistemaker le. Pulm Pharmacol Ther. 2014 Dec;29(2):96-107. doi: 10.1016/j.pupt.2014.07.005. Epub 2014 Jul 23. Pulm Pharmacol Ther. 2014. PMID: 25062835 Review.

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Regulation of airway inflammation and remodeling by muscarinic receptors: perspectives on anticholinergic therapy in asthma and COPD.

Kistemaker LE, Oenema TA, Meurs H, Gosens R. Kistemaker LE, et al. Life Sci. 2012 Nov 27;91(21-22):1126-33. doi: 10.1016/j.lfs.2012.02.021. Epub 2012 Mar 3. Life Sci. 2012. PMID: 22406302 Review.

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Second M₃ muscarinic receptor binding site contributes to bronchoprotection by tiotropium.

Kistemaker LEM, Elzinga CRS, Tautermann CS, Pieper MP, Seeliger D, Alikhil S, Schmidt M, Meurs H, Gosens R. Kistemaker LEM, et al. Br J Pharmacol. 2019 Aug;176(16):2864-2876. doi: 10.1111/bph.14707. Epub 2019 Jul 2. Br J Pharmacol. 2019. PMID: 31077341 Free PMC article.

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