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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 1
2011 3
2012 1
2013 1
2016 2
2017 1
2018 3
2019 2
2020 2
2021 4
2022 4
2023 0

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22 results

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Page 1
Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax.
King HM, Rana S, Kubica SP, Mallareddy JR, Kizhake S, Ezell EL, Zahid M, Naldrett MJ, Alvarez S, Law HC, Woods NT, Natarajan A. King HM, et al. Among authors: kizhake s. Bioorg Med Chem Lett. 2021 Jul 1;43:128061. doi: 10.1016/j.bmcl.2021.128061. Epub 2021 Apr 23. Bioorg Med Chem Lett. 2021. PMID: 33895280 Free PMC article.
Selective degradation of CDK6 by a palbociclib based PROTAC.
Rana S, Bendjennat M, Kour S, King HM, Kizhake S, Zahid M, Natarajan A. Rana S, et al. Among authors: kizhake s. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1375-1379. doi: 10.1016/j.bmcl.2019.03.035. Epub 2019 Mar 26. Bioorg Med Chem Lett. 2019. PMID: 30935795 Free PMC article.
Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth.
Napoleon JV, Sagar S, Kubica SP, Boghean L, Kour S, King HM, Sonawane YA, Crawford AJ, Gautam N, Kizhake S, Bialk PA, Kmiec E, Mallareddy JR, Patil PP, Rana S, Singh S, Prahlad J, Grandgenett PM, Borgstahl GEO, Ghosal G, Alnouti Y, Hollingsworth MA, Radhakrishnan P, Natarajan A. Napoleon JV, et al. Among authors: kizhake s. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2115071119. doi: 10.1073/pnas.2115071119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476515 Free PMC article.
Symbiotic prodrugs (SymProDs) dual targeting of NFkappaB and CDK.
Rana S, Kour S, Sonawane YA, Robb CM, Contreras JI, Kizhake S, Zahid M, Karpf AR, Natarajan A. Rana S, et al. Among authors: kizhake s. Chem Biol Drug Des. 2020 Aug;96(2):773-784. doi: 10.1111/cbdd.13684. Epub 2020 Apr 22. Chem Biol Drug Des. 2020. PMID: 32237047 Free PMC article.
Correction: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.
Robb CM, Kour S, Contreras JI, Agarwal E, Barger CJ, Rana S, Sonawane Y, Neilsen BK, Taylor M, Kizhake S, Thakare RN, Chowdhury S, Wang J, Black JD, Hollingsworth MA, Brattain MG, Natarajan A. Robb CM, et al. Among authors: kizhake s. Oncotarget. 2020 Jun 23;11(25):2462-2463. doi: 10.18632/oncotarget.27403. eCollection 2020 Jun 23. Oncotarget. 2020. PMID: 32637035 Free PMC article.
22 results