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Year Number of Results
1998 1
1999 4
2000 2
2002 1
2003 1
2010 3
2014 1
2016 1
2017 1
2019 2
2020 2
2021 6
2022 2
2023 6
2024 4
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35 results

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Page 1
MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus.
de Blank PMK, Gross AM, Akshintala S, Blakeley JO, Bollag G, Cannon A, Dombi E, Fangusaro J, Gelb BD, Hargrave D, Kim A, Klesse LJ, Loh M, Martin S, Moertel C, Packer R, Payne JM, Rauen KA, Rios JJ, Robison N, Schorry EK, Shannon K, Stevenson DA, Stieglitz E, Ullrich NJ, Walsh KS, Weiss BD, Wolters PL, Yohay K, Yohe ME, Widemann BC, Fisher MJ. de Blank PMK, et al. Among authors: klesse lj. Neuro Oncol. 2022 Nov 2;24(11):1845-1856. doi: 10.1093/neuonc/noac165. Neuro Oncol. 2022. PMID: 35788692 Free PMC article. Review.
Targeted Therapies for the Neurofibromatoses.
Sanchez LD, Bui A, Klesse LJ. Sanchez LD, et al. Among authors: klesse lj. Cancers (Basel). 2021 Nov 30;13(23):6032. doi: 10.3390/cancers13236032. Cancers (Basel). 2021. PMID: 34885143 Free PMC article. Review.
Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma.
Kumar R, Smith KS, Deng M, Terhune C, Robinson GW, Orr BA, Liu APY, Lin T, Billups CA, Chintagumpala M, Bowers DC, Hassall TE, Hansford JR, Khuong-Quang DA, Crawford JR, Bendel AE, Gururangan S, Schroeder K, Bouffet E, Bartels U, Fisher MJ, Cohn R, Partap S, Kellie SJ, McCowage G, Paulino AC, Rutkowski S, Fleischhack G, Dhall G, Klesse LJ, Leary S, Nazarian J, Kool M, Wesseling P, Ryzhova M, Zheludkova O, Golanov AV, McLendon RE, Packer RJ, Dunham C, Hukin J, Fouladi M, Faria CC, Pimentel J, Walter AW, Jabado N, Cho YJ, Perreault S, Croul SE, Zapotocky M, Hawkins C, Tabori U, Taylor MD, Pfister SM, Klimo P Jr, Boop FA, Ellison DW, Merchant TE, Onar-Thomas A, Korshunov A, Jones DTW, Gajjar A, Ramaswamy V, Northcott PA. Kumar R, et al. Among authors: klesse lj. J Clin Oncol. 2021 Mar 1;39(7):807-821. doi: 10.1200/JCO.20.01359. Epub 2021 Jan 27. J Clin Oncol. 2021. PMID: 33502920 Free PMC article.
Genomic profiling of subcutaneous patient-derived xenografts reveals immune constraints on tumor evolution in childhood solid cancer.
He F, Bandyopadhyay AM, Klesse LJ, Rogojina A, Chun SH, Butler E, Hartshorne T, Holland T, Garcia D, Weldon K, Prado LP, Langevin AM, Grimes AC, Sugalski A, Shah S, Assanasen C, Lai Z, Zou Y, Kurmashev D, Xu L, Xie Y, Chen Y, Wang X, Tomlinson GE, Skapek SX, Houghton PJ, Kurmasheva RT, Zheng S. He F, et al. Among authors: klesse lj. Nat Commun. 2023 Nov 22;14(1):7600. doi: 10.1038/s41467-023-43373-1. Nat Commun. 2023. PMID: 37990009 Free PMC article.
Recent progress in the treatment of cancer in children.
Butler E, Ludwig K, Pacenta HL, Klesse LJ, Watt TC, Laetsch TW. Butler E, et al. Among authors: klesse lj. CA Cancer J Clin. 2021 Jul;71(4):315-332. doi: 10.3322/caac.21665. Epub 2021 Apr 1. CA Cancer J Clin. 2021. PMID: 33793968 Free article. Review.
ReNeu: A Pivotal, Phase IIb Trial of Mirdametinib in Adults and Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma.
Moertel CL, Hirbe AC, Shuhaiber HH, Bielamowicz K, Sidhu A, Viskochil D, Weber MD, Lokku A, Smith LM, Foreman NK, Hajjar FM, McNall-Knapp RY, Weintraub L, Antony R, Franson AT, Meade J, Schiff D, Walbert T, Ambady P, Bota DA, Campen CJ, Kaur G, Klesse LJ, Maraka S, Moots PL, Nevel K, Bornhorst M, Aguilar-Bonilla A, Chagnon S, Dalvi N, Gupta P, Khatib Z, Metrock LK, Nghiemphu PL, Roberts RD, Robison NJ, Sadighi Z, Stapleton S, Babovic-Vuksanovic D, Gershon TR; ReNeu Trial Investigators; ReNeu Study Investigators. Moertel CL, et al. Among authors: klesse lj. J Clin Oncol. 2025 Feb 20;43(6):716-729. doi: 10.1200/JCO.24.01034. Epub 2024 Nov 8. J Clin Oncol. 2025. PMID: 39514826 Free PMC article. Clinical Trial.
Insights into the Pathogenesis of NF1-Associated Neoplasms.
Bui A, Jiang C, McKay RM, Klesse LJ, Le LQ. Bui A, et al. Among authors: klesse lj. JID Innov. 2021 Sep;1(3):100044. doi: 10.1016/j.xjidi.2021.100044. Epub 2021 Aug 20. JID Innov. 2021. PMID: 34604833 Free PMC article.
Comprehensive characterization of patient-derived xenograft models of pediatric leukemia.
Rogojina A, Klesse LJ, Butler E, Kim J, Zhang H, Xiao X, Guo L, Zhou Q, Hartshorne T, Garcia D, Weldon K, Holland T, Bandyopadhyay A, Prado LP, Wang S, Yang DM, Langevan AM, Zou Y, Grimes AC, Assanasen C, Gidvani-Diaz V, Zheng S, Lai Z, Chen Y, Xie Y, Tomlinson GE, Skapek SX, Kurmasheva RT, Houghton PJ, Xu L. Rogojina A, et al. Among authors: klesse lj. iScience. 2023 Oct 10;26(11):108171. doi: 10.1016/j.isci.2023.108171. eCollection 2023 Nov 17. iScience. 2023. PMID: 37915590 Free PMC article.
The role of MEK inhibition in pediatric low-grade gliomas.
Sheikh SR, Klesse LJ, Mangum R, Bui A, Siegel BI, Abdelbaki MS, Patel NJ. Sheikh SR, et al. Among authors: klesse lj. Front Oncol. 2024 Dec 20;14:1503894. doi: 10.3389/fonc.2024.1503894. eCollection 2024. Front Oncol. 2024. PMID: 39759151 Free PMC article. Review.
35 results