Kohlhagen G[au] - Search Results

Year	Number of Results
1993	2
1994	5
1995	7
1996	1
1997	3
1998	3
1999	6
2000	5
2001	5
2002	7
2003	8
2004	12
2005	5
2006	6
2023	0

1

Repair of and checkpoint response to topoisomerase I-mediated DNA damage.

Pommier Y, Redon C, Rao VA, Seiler JA, Sordet O, Takemura H, Antony S, Meng L, Liao Z, Kohlhagen G, Zhang H, Kohn KW. Pommier Y, et al. Among authors: kohlhagen g. Mutat Res. 2003 Nov 27;532(1-2):173-203. doi: 10.1016/j.mrfmmm.2003.08.016. Mutat Res. 2003. PMID: 14643436 Review.

2

Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors.

Pommier Y, Leteurtre F, Fesen MR, Fujimori A, Bertrand R, Solary E, Kohlhagen G, Kohn KW. Pommier Y, et al. Among authors: kohlhagen g. Cancer Invest. 1994;12(5):530-42. doi: 10.3109/07357909409021413. Cancer Invest. 1994. PMID: 7922710 Review. No abstract available.

3

Human mitochondrial topoisomerase I.

Zhang H, Barceló JM, Lee B, Kohlhagen G, Zimonjic DB, Popescu NC, Pommier Y. Zhang H, et al. Among authors: kohlhagen g. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10608-13. doi: 10.1073/pnas.191321998. Epub 2001 Aug 28. Proc Natl Acad Sci U S A. 2001. PMID: 11526219 Free PMC article.

4

Different effects on human topoisomerase I by minor groove and intercalated deoxyguanosine adducts derived from two polycyclic aromatic hydrocarbon diol epoxides at or near a normal cleavage site.

Pommier Y, Kohlhagen G, Laco GS, Kroth H, Sayer JM, Jerina DM. Pommier Y, et al. Among authors: kohlhagen g. J Biol Chem. 2002 Apr 19;277(16):13666-72. doi: 10.1074/jbc.M200209200. Epub 2002 Feb 6. J Biol Chem. 2002. PMID: 11832494 Free article.

5

Synthesis and evaluation of indenoisoquinoline topoisomerase I inhibitors substituted with nitrogen heterocycles.

Nagarajan M, Morrell A, Ioanoviciu A, Antony S, Kohlhagen G, Agama K, Hollingshead M, Pommier Y, Cushman M. Nagarajan M, et al. Among authors: kohlhagen g. J Med Chem. 2006 Oct 19;49(21):6283-9. doi: 10.1021/jm060564z. J Med Chem. 2006. PMID: 17034134 Free PMC article.

6

Apoptotic topoisomerase I-DNA complexes induced by staurosporine-mediated oxygen radicals.

Sordet O, Khan QA, Plo I, Pourquier P, Urasaki Y, Yoshida A, Antony S, Kohlhagen G, Solary E, Saparbaev M, Laval J, Pommier Y. Sordet O, et al. Among authors: kohlhagen g. J Biol Chem. 2004 Nov 26;279(48):50499-504. doi: 10.1074/jbc.M410277200. Epub 2004 Sep 22. J Biol Chem. 2004. PMID: 15448130 Free article.

7

Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis.

Sordet O, Liao Z, Liu H, Antony S, Stevens EV, Kohlhagen G, Fu H, Pommier Y. Sordet O, et al. Among authors: kohlhagen g. J Biol Chem. 2004 Aug 6;279(32):33968-75. doi: 10.1074/jbc.M404620200. Epub 2004 Jun 3. J Biol Chem. 2004. PMID: 15178684 Free article.

8

Topoisomerase I and II Activity Assays.

Pourquier P, Kohlhagen G, Ueng LM, Pommier Y. Pourquier P, et al. Among authors: kohlhagen g. Methods Mol Med. 1999;28:95-110. doi: 10.1385/1-59259-687-8:95. Methods Mol Med. 1999. PMID: 21374031

9

Gemcitabine (2',2'-difluoro-2'-deoxycytidine), an antimetabolite that poisons topoisomerase I.

Pourquier P, Gioffre C, Kohlhagen G, Urasaki Y, Goldwasser F, Hertel LW, Yu S, Pon RT, Gmeiner WH, Pommier Y. Pourquier P, et al. Among authors: kohlhagen g. Clin Cancer Res. 2002 Aug;8(8):2499-504. Clin Cancer Res. 2002. PMID: 12171875

10

Synthesis of new indeno[1,2-c]isoquinolines: cytotoxic non-camptothecin topoisomerase I inhibitors.

Cushman M, Jayaraman M, Vroman JA, Fukunaga AK, Fox BM, Kohlhagen G, Strumberg D, Pommier Y. Cushman M, et al. Among authors: kohlhagen g. J Med Chem. 2000 Oct 5;43(20):3688-98. doi: 10.1021/jm000029d. J Med Chem. 2000. PMID: 11020283

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