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Year Number of Results
2014 2
2016 3
2017 2
2018 1
2021 2
2022 1
2023 4

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Page 1
Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification.
Liu L, Toung JM, Jassowicz AF, Vijayaraghavan R, Kang H, Zhang R, Kruglyak KM, Huang HJ, Hinoue T, Shen H, Salathia NS, Hong DS, Naing A, Subbiah V, Piha-Paul SA, Bibikova M, Granger G, Barnes B, Shen R, Gutekunst K, Fu S, Tsimberidou AM, Lu C, Eng C, Moulder SL, Kopetz ES, Amaria RN, Meric-Bernstam F, Laird PW, Fan JB, Janku F. Liu L, et al. Among authors: kruglyak km. Ann Oncol. 2018 Jun 1;29(6):1445-1453. doi: 10.1093/annonc/mdy119. Ann Oncol. 2018. PMID: 29635542 Free PMC article.
Clinical validation of a next-generation sequencing-based multi-cancer early detection "liquid biopsy" blood test in over 1,000 dogs using an independent testing set: The CANcer Detection in Dogs (CANDiD) study.
Flory A, Kruglyak KM, Tynan JA, McLennan LM, Rafalko JM, Fiaux PC, Hernandez GE, Marass F, Nakashe P, Ruiz-Perez CA, Fath DM, Jennings T, Motalli-Pepio R, Wotrang K, McCleary-Wheeler AL, Lana S, Phillips B, Flesner BK, Leibman NF, LaDue T, Tripp CD, Coomber BL, Woods JP, Miller M, Aiken SW, Wolf-Ringwall A, Borgatti A, Kraska K, Thomson CB, Kosanovich Cahalane A, Murray RL, Kisseberth WC, Camps-Palau MA, Floch F, Beaudu-Lange C, Klajer-Peres A, Keravel O, Fribourg-Blanc LA, Mazetier PC, Marco A, McLeod MB, Portillo E, Clark TS, Judd S, Feinberg CK, Benitez M, Runyan C, Hackett L, Lafey S, Richardson D, Vineyard S, Tefend Campbell M, Dharajiya N, Jensen TJ, van den Boom D, Diaz LA Jr, Grosu DS, Polk A, Marsal K, Hicks SC, Lytle KM, Holtvoigt L, Chibuk J, Chorny I, Tsui DWY. Flory A, et al. Among authors: kruglyak km. PLoS One. 2022 Apr 26;17(4):e0266623. doi: 10.1371/journal.pone.0266623. eCollection 2022. PLoS One. 2022. PMID: 35471999 Free PMC article.
Horizons in Veterinary Precision Oncology: Fundamentals of Cancer Genomics and Applications of Liquid Biopsy for the Detection, Characterization, and Management of Cancer in Dogs.
Chibuk J, Flory A, Kruglyak KM, Leibman N, Nahama A, Dharajiya N, van den Boom D, Jensen TJ, Friedman JS, Shen MR, Clemente-Vicario F, Chorny I, Tynan JA, Lytle KM, Holtvoigt LE, Murtaza M, Diaz LA Jr, Tsui DWY, Grosu DS. Chibuk J, et al. Among authors: kruglyak km. Front Vet Sci. 2021 Mar 23;8:664718. doi: 10.3389/fvets.2021.664718. eCollection 2021. Front Vet Sci. 2021. PMID: 33834049 Free PMC article. Review.
Clinical experience with next-generation sequencing-based liquid biopsy testing for cancer detection in dogs: a review of 1,500 consecutive clinical cases.
O'Kell AL, Lytle KM, Cohen TA, Wong LK, Sandford E, Rafalko JM, Brandstetter G, DiMarzio LR, Phelps-Dunn A, Rosentel MC, Warren CD, McCleary-Wheeler AL, Fiaux PC, Marass F, Marshall MA, Ruiz-Perez CA, Kruglyak KM, Tynan JA, Hicks SC, Grosu DS, Chibuk J, Chorny I, Tsui DWY, Flory A. O'Kell AL, et al. Among authors: kruglyak km. J Am Vet Med Assoc. 2023 Mar 17;261(6):827-836. doi: 10.2460/javma.22.11.0526. Print 2023 Jun 1. J Am Vet Med Assoc. 2023. PMID: 36965477 Review.
Fetal aneuploidy screening with cell-free DNA in late gestation.
Taneja PA, Prosen TL, de Feo E, Kruglyak KM, Halks-Miller M, Curnow KJ, Bhatt S. Taneja PA, et al. Among authors: kruglyak km. J Matern Fetal Neonatal Med. 2017 Feb;30(3):338-342. doi: 10.3109/14767058.2016.1172566. Epub 2016 Apr 28. J Matern Fetal Neonatal Med. 2017. PMID: 27124739
Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of more than 3,000 dogs: Determining the optimal age to initiate cancer screening in canine patients.
Rafalko JM, Kruglyak KM, McCleary-Wheeler AL, Goyal V, Phelps-Dunn A, Wong LK, Warren CD, Brandstetter G, Rosentel MC, DiMarzio L, McLennan LM, O'Kell AL, Cohen TA, Grosu DS, Chibuk J, Tsui DWY, Chorny I, Flory A. Rafalko JM, et al. Among authors: kruglyak km. PLoS One. 2023 Feb 1;18(2):e0280795. doi: 10.1371/journal.pone.0280795. eCollection 2023. PLoS One. 2023. PMID: 36724177 Free PMC article.
Cancer detection in clinical practice and using blood-based liquid biopsy: A retrospective audit of over 350 dogs.
Flory A, McLennan L, Peet B, Kroll M, Stuart D, Brown D, Stuebner K, Phillips B, Coomber BL, Woods JP, Miller M, Tripp CD, Wolf-Ringwall A, Kruglyak KM, McCleary-Wheeler AL, Phelps-Dunn A, Wong LK, Warren CD, Brandstetter G, Rosentel MC, DiMarzio LR, O'Kell AL, Cohen TA, Grosu DS, Chibuk J, Tsui DWY, Chorny I, Rafalko JM. Flory A, et al. Among authors: kruglyak km. J Vet Intern Med. 2023 Jan;37(1):258-267. doi: 10.1111/jvim.16616. Epub 2023 Jan 20. J Vet Intern Med. 2023. PMID: 36661398 Free PMC article.
Detection of Age-Related Somatic Alterations in Canine Blood Using Next-Generation Sequencing-Based Liquid Biopsy: An Analysis of over 4800 Dogs.
Kruglyak KM, O'Kell AL, Cohen TA, Marshall MA, Ruiz-Perez CA, Marass F, Tynan JA, Hicks SC, Lytle KM, Phelps-Dunn A, Brandstetter G, Warren CD, DiMarzio LR, Rosentel MC, Wong LK, McLennan LM, Rafalko JM, Grosu DS, Chibuk J, Chorny I, McCleary-Wheeler AL, Flory A, Tsui DWY. Kruglyak KM, et al. Vet Sci. 2023 Jul 11;10(7):455. doi: 10.3390/vetsci10070455. Vet Sci. 2023. PMID: 37505860 Free PMC article.
14 results