Kulcsár PI[au] - Search Results

Year	Number of Results
2012	1
2013	2
2014	1
2016	1
2017	2
2018	2
2020	2
2021	3
2022	2
2023	2
2024	2

1

Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs.

Marquart KF, Mathis N, Mollaysa A, Müller S, Kissling L, Rothgangl T, Schmidheini L, Kulcsár PI, Allam A, Kaufmann MM, Matsushita M, Haenggi T, Cathomen T, Kopf M, Krauthammer M, Schwank G. Marquart KF, et al. Among authors: kulcsar pi. Nat Methods. 2024 Nov;21(11):2084-2093. doi: 10.1038/s41592-024-02418-z. Epub 2024 Sep 23. Nat Methods. 2024. PMID: 39313558

2

Identification of New Interactions between Endolysosomal Tethering Factors.

Simon-Vecsei Z, Sőth Á, Lőrincz P, Rubics A, Tálas A, Kulcsár PI, Juhász G. Simon-Vecsei Z, et al. Among authors: kulcsar pi. J Mol Biol. 2021 Jun 25;433(13):166965. doi: 10.1016/j.jmb.2021.166965. Epub 2021 Mar 27. J Mol Biol. 2021. PMID: 33781757 Free article.

3

PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully prime edited cells.

Simon DA, Tálas A, Kulcsár PI, Biczók Z, Krausz SL, Várady G, Welker E. Simon DA, et al. Among authors: kulcsar pi. Elife. 2022 Feb 23;11:e69504. doi: 10.7554/eLife.69504. Elife. 2022. PMID: 35196219 Free PMC article.

4

SuperFi-Cas9 exhibits remarkable fidelity but severely reduced activity yet works effectively with ABE8e.

Kulcsár PI, Tálas A, Ligeti Z, Krausz SL, Welker E. Kulcsár PI, et al. Nat Commun. 2022 Nov 11;13(1):6858. doi: 10.1038/s41467-022-34527-8. Nat Commun. 2022. PMID: 36369279 Free PMC article.

5

Position-dependent sequence motif preferences of SpCas9 are largely determined by scaffold-complementary spacer motifs.

Huszár K, Welker Z, Györgypál Z, Tóth E, Ligeti Z, Kulcsár PI, Dancsó J, Tálas A, Krausz SL, Varga É, Welker E. Huszár K, et al. Among authors: kulcsar pi. Nucleic Acids Res. 2023 Jun 23;51(11):5847-5863. doi: 10.1093/nar/gkad323. Nucleic Acids Res. 2023. PMID: 37140059 Free PMC article.

6

A method for characterizing Cas9 variants via a one-million target sequence library of self-targeting sgRNAs.

Tálas A, Huszár K, Kulcsár PI, Varga JK, Varga É, Tóth E, Welker Z, Erdős G, Pach PF, Welker Á, Györgypál Z, Tusnády GE, Welker E. Tálas A, et al. Among authors: kulcsar pi. Nucleic Acids Res. 2021 Apr 6;49(6):e31. doi: 10.1093/nar/gkaa1220. Nucleic Acids Res. 2021. PMID: 33450024 Free PMC article.

7

A cleavage rule for selection of increased-fidelity SpCas9 variants with high efficiency and no detectable off-targets.

Kulcsár PI, Tálas A, Ligeti Z, Tóth E, Rakvács Z, Bartos Z, Krausz SL, Welker Á, Végi VL, Huszár K, Welker E. Kulcsár PI, et al. Nat Commun. 2023 Sep 16;14(1):5746. doi: 10.1038/s41467-023-41393-5. Nat Commun. 2023. PMID: 37717069 Free PMC article.

8

Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47 ^phox -deficient chronic granulomatous disease.

Siow KM, Güngör M, Wrona D, Raimondi F, Pastukhov O, Tsapogas P, Menzi T, Schmitz M, Kulcsár PI, Schwank G, Schulz A, Jinek M, Modlich U, Siler U, Reichenbach J. Siow KM, et al. Among authors: kulcsar pi. Mol Ther Nucleic Acids. 2024 May 24;35(3):102229. doi: 10.1016/j.omtn.2024.102229. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 38952440 Free PMC article.

9

Blackjack mutations improve the on-target activities of increased fidelity variants of SpCas9 with 5'G-extended sgRNAs.

Kulcsár PI, Tálas A, Tóth E, Nyeste A, Ligeti Z, Welker Z, Welker E. Kulcsár PI, et al. Nat Commun. 2020 Mar 6;11(1):1223. doi: 10.1038/s41467-020-15021-5. Nat Commun. 2020. PMID: 32144253 Free PMC article.

10

BEAR reveals that increased fidelity variants can successfully reduce the mismatch tolerance of adenine but not cytosine base editors.

Tálas A, Simon DA, Kulcsár PI, Varga É, Krausz SL, Welker E. Tálas A, et al. Among authors: kulcsar pi. Nat Commun. 2021 Nov 3;12(1):6353. doi: 10.1038/s41467-021-26461-y. Nat Commun. 2021. PMID: 34732717 Free PMC article.

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