Kumondai M[au] - Search Results

Year	Number of Results
2015	1
2016	3
2017	3
2018	6
2019	2
2020	4
2021	3
2022	3

1

Heterologous expression of high-activity cytochrome P450 in mammalian cells.

Kumondai M, Hishinuma E, Gutiérrez Rico EM, Ito A, Nakanishi Y, Saigusa D, Hirasawa N, Hiratsuka M. Kumondai M, et al. Sci Rep. 2020 Aug 25;10(1):14193. doi: 10.1038/s41598-020-71035-5. Sci Rep. 2020. PMID: 32843676 Free PMC article.

2

Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6β-Hydroxylation.

Kumondai M, Gutiérrez Rico EM, Hishinuma E, Ueda A, Saito S, Saigusa D, Tadaka S, Kinoshita K, Nakayoshi T, Oda A, Abe A, Maekawa M, Mano N, Hirasawa N, Hiratsuka M. Kumondai M, et al. Drug Metab Dispos. 2021 Mar;49(3):212-220. doi: 10.1124/dmd.120.000261. Epub 2020 Dec 31. Drug Metab Dispos. 2021. PMID: 33384383

3

Functional Assessment of 12 Rare Allelic CYP2C9 Variants Identified in a Population of 4773 Japanese Individuals.

Kumondai M, Ito A, Gutiérrez Rico EM, Hishinuma E, Ueda A, Saito S, Nakayoshi T, Oda A, Tadaka S, Kinoshita K, Maekawa M, Mano N, Hirasawa N, Hiratsuka M. Kumondai M, et al. J Pers Med. 2021 Feb 2;11(2):94. doi: 10.3390/jpm11020094. J Pers Med. 2021. PMID: 33540768 Free PMC article.

4

Functional Characterization of 21 Rare Allelic CYP1A2 Variants Identified in a Population of 4773 Japanese Individuals by Assessing Phenacetin O-Deethylation.

Kumondai M, Gutiérrez Rico EM, Hishinuma E, Nakanishi Y, Yamazaki S, Ueda A, Saito S, Tadaka S, Kinoshita K, Saigusa D, Nakayoshi T, Oda A, Hirasawa N, Hiratsuka M. Kumondai M, et al. J Pers Med. 2021 Jul 22;11(8):690. doi: 10.3390/jpm11080690. J Pers Med. 2021. PMID: 34442334 Free PMC article.

5

An optimized prediction framework to assess the functional impact of pharmacogenetic variants.

Zhou Y, Mkrtchian S, Kumondai M, Hiratsuka M, Lauschke VM. Zhou Y, et al. Among authors: kumondai m. Pharmacogenomics J. 2019 Apr;19(2):115-126. doi: 10.1038/s41397-018-0044-2. Epub 2018 Sep 12. Pharmacogenomics J. 2019. PMID: 30206299 Free PMC article.

6

Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation.

Watanabe T, Saito T, Rico EMG, Hishinuma E, Kumondai M, Maekawa M, Oda A, Saigusa D, Saito S, Yasuda J, Nagasaki M, Minegishi N, Yamamoto M, Yamaguchi H, Mano N, Hirasawa N, Hiratsuka M. Watanabe T, et al. Among authors: kumondai m. Biochem Pharmacol. 2018 Oct;156:420-430. doi: 10.1016/j.bcp.2018.09.010. Epub 2018 Sep 8. Biochem Pharmacol. 2018. PMID: 30201214

7

Functional characterization of 50 CYP2D6 allelic variants by assessing primaquine 5-hydroxylation.

Saito T, Gutiérrez Rico EM, Kikuchi A, Kaneko A, Kumondai M, Akai F, Saigusa D, Oda A, Hirasawa N, Hiratsuka M. Saito T, et al. Among authors: kumondai m. Drug Metab Pharmacokinet. 2018 Dec;33(6):250-257. doi: 10.1016/j.dmpk.2018.08.004. Epub 2018 Aug 25. Drug Metab Pharmacokinet. 2018. PMID: 30366777

8

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics.

Santos M, Niemi M, Hiratsuka M, Kumondai M, Ingelman-Sundberg M, Lauschke VM, Rodríguez-Antona C. Santos M, et al. Among authors: kumondai m. Genet Med. 2018 Jun;20(6):622-629. doi: 10.1038/gim.2017.156. Epub 2017 Oct 26. Genet Med. 2018. PMID: 29261188 Free article.

9

Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes.

Hendriks DFG, Vorrink SU, Smutny T, Sim SC, Nordling Å, Ullah S, Kumondai M, Jones BC, Johansson I, Andersson TB, Lauschke VM, Ingelman-Sundberg M. Hendriks DFG, et al. Among authors: kumondai m. Clin Pharmacol Ther. 2020 Oct;108(4):844-855. doi: 10.1002/cpt.1860. Epub 2020 May 22. Clin Pharmacol Ther. 2020. PMID: 32320483

10

CYP2D6 genotyping analysis and functional characterization of novel allelic variants in a Ni-Vanuatu and Kenyan population by assessing dextromethorphan O-demethylation activity.

Gutiérrez Rico EM, Kikuchi A, Saito T, Kumondai M, Hishinuma E, Kaneko A, Chan CW, Gitaka J, Nakayoshi T, Oda A, Saito S, Hirasawa N, Hiratsuka M. Gutiérrez Rico EM, et al. Among authors: kumondai m. Drug Metab Pharmacokinet. 2020 Feb;35(1):89-101. doi: 10.1016/j.dmpk.2019.07.003. Epub 2019 Jul 20. Drug Metab Pharmacokinet. 2020. PMID: 32037159

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