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Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo.

Cabrita I, Kraus A, Scholz JK, Skoczynski K, Schreiber R, Kunzelmann K, Buchholz B. Cabrita I, et al. Among authors: kunzelmann k. Nat Commun. 2020 Aug 28;11(1):4320. doi: 10.1038/s41467-020-18104-5. Nat Commun. 2020. PMID: 32859916 Free PMC article.

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Anoctamins.

Kunzelmann K, Tian Y, Martins JR, Faria D, Kongsuphol P, Ousingsawat J, Thevenod F, Roussa E, Rock J, Schreiber R. Kunzelmann K, et al. Pflugers Arch. 2011 Aug;462(2):195-208. doi: 10.1007/s00424-011-0975-9. Epub 2011 May 21. Pflugers Arch. 2011. PMID: 21607626 Review.

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TMEM16A is indispensable for basal mucus secretion in airways and intestine.

Benedetto R, Cabrita I, Schreiber R, Kunzelmann K. Benedetto R, et al. Among authors: kunzelmann k. FASEB J. 2019 Mar;33(3):4502-4512. doi: 10.1096/fj.201801333RRR. Epub 2018 Dec 26. FASEB J. 2019. PMID: 30586313

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Bicarbonate in cystic fibrosis.

Kunzelmann K, Schreiber R, Hadorn HB. Kunzelmann K, et al. J Cyst Fibros. 2017 Nov;16(6):653-662. doi: 10.1016/j.jcf.2017.06.005. Epub 2017 Jul 18. J Cyst Fibros. 2017. PMID: 28732801 Free article. Review.

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Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site.

Treharne KJ, Crawford RM, Xu Z, Chen JH, Best OG, Schulte EA, Gruenert DC, Wilson SM, Sheppard DN, Kunzelmann K, Mehta A. Treharne KJ, et al. Among authors: kunzelmann k. J Biol Chem. 2008 Sep 5;283(36):25103. J Biol Chem. 2008. PMID: 18810786 Free PMC article. No abstract available.

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Phenytoin inhibits necroptosis.

von Mässenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A. von Mässenhausen A, et al. Among authors: kunzelmann k. Cell Death Dis. 2018 Mar 2;9(3):359. doi: 10.1038/s41419-018-0394-3. Cell Death Dis. 2018. PMID: 29500402 Free PMC article.

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Differential effects of anoctamins on intracellular calcium signals.

Cabrita I, Benedetto R, Fonseca A, Wanitchakool P, Sirianant L, Skryabin BV, Schenk LK, Pavenstädt H, Schreiber R, Kunzelmann K. Cabrita I, et al. Among authors: kunzelmann k. FASEB J. 2017 May;31(5):2123-2134. doi: 10.1096/fj.201600797RR. Epub 2017 Feb 9. FASEB J. 2017. PMID: 28183802

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Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression.

Hagmann H, Mangold N, Rinschen MM, Koenig T, Kunzelmann K, Schermer B, Benzing T, Brinkkoetter PT. Hagmann H, et al. Among authors: kunzelmann k. FASEB J. 2018 Jan;32(1):208-219. doi: 10.1096/fj.201700309R. Epub 2017 Sep 6. FASEB J. 2018. PMID: 28877958 Free PMC article.

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The molecular mechanism of CFTR- and secretin-dependent renal bicarbonate excretion.

Berg P, Svendsen SL, Sorensen MV, Schreiber R, Kunzelmann K, Leipziger J. Berg P, et al. Among authors: kunzelmann k. J Physiol. 2021 Jun;599(12):3003-3011. doi: 10.1113/JP281285. Epub 2021 May 29. J Physiol. 2021. PMID: 33963548 Free article. Review.

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CyFi-MAP: an interactive pathway-based resource for cystic fibrosis.

Pereira C, Mazein A, Farinha CM, Gray MA, Kunzelmann K, Ostaszewski M, Balaur I, Amaral MD, Falcao AO. Pereira C, et al. Among authors: kunzelmann k. Sci Rep. 2021 Nov 15;11(1):22223. doi: 10.1038/s41598-021-01618-3. Sci Rep. 2021. PMID: 34782688 Free PMC article.

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