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2020 8
2021 5
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13 results
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Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
Mathew D, Giles JR, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Ramage H, Cherry S, Hensley SE, Apostolidis SA, Huang AC, Vella LA; UPenn COVID Processing Unit, Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: kuthuru o. Science. 2020 Sep 4;369(6508):eabc8511. doi: 10.1126/science.abc8511. Epub 2020 Jul 15. Science. 2020. PMID: 32669297 Free PMC article.
Comprehensive mapping of immune perturbations associated with severe COVID-19.
Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum RS, Mathew D, Baxter AE, Vella LA, Kuthuru O, Apostolidis SA, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR. Kuri-Cervantes L, et al. Among authors: kuthuru o. Sci Immunol. 2020 Jul 15;5(49):eabd7114. doi: 10.1126/sciimmunol.abd7114. Sci Immunol. 2020. PMID: 32669287 Free PMC article.
Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection.
Kuri-Cervantes L, Pampena MB, Meng W, Rosenfeld AM, Ittner CAG, Weisman AR, Agyekum R, Mathew D, Baxter AE, Vella L, Kuthuru O, Apostolidis S, Bershaw L, Dougherty J, Greenplate AR, Pattekar A, Kim J, Han N, Gouma S, Weirick ME, Arevalo CP, Bolton MJ, Goodwin EC, Anderson EM, Hensley SE, Jones TK, Mangalmurti NS, Luning Prak ET, Wherry EJ, Meyer NJ, Betts MR. Kuri-Cervantes L, et al. Among authors: kuthuru o. bioRxiv. 2020 May 18:2020.05.18.101717. doi: 10.1101/2020.05.18.101717. Preprint. bioRxiv. 2020. PMID: 32511394 Free PMC article.
SARS-CoV-2 seroprevalence among parturient women in Philadelphia.
Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Gerber JS, Arevalo CP, Bolton MJ, Weirick ME, Goodwin EC, Anderson EM, Greenplate AR, Kim J, Han N, Pattekar A, Dougherty J, Kuthuru O, Mathew D, Baxter AE, Vella LA, Weaver J, Verma A, Leite R, Morris JS, Rader DJ, Elovitz MA, Wherry EJ, Puopolo KM, Hensley SE. Flannery DD, et al. Among authors: kuthuru o. Sci Immunol. 2020 Jul 29;5(49):eabd5709. doi: 10.1126/sciimmunol.abd5709. Sci Immunol. 2020. PMID: 32727884 Free PMC article.
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions.
Mathew D, Giles JR, Baxter AE, Greenplate AR, Wu JE, Alanio C, Oldridge DA, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Hensley SE, Apostolidis S, Huang AC, Vella LA; UPenn COVID Processing Unit, Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: kuthuru o. bioRxiv. 2020 May 23:2020.05.20.106401. doi: 10.1101/2020.05.20.106401. Preprint. bioRxiv. 2020. PMID: 32511371 Free PMC article. Updated.
Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19.
Vella L, Giles JR, Baxter AE, Oldridge DA, Diorio C, Kuri-Cervantes L, Alanio C, Pampena MB, Wu JE, Chen Z, Huang YJ, Anderson EM, Gouma S, McNerney KO, Chase J, Burudpakdee C, Lee JH, Apostolidis SA, Huang AC, Mathew D, Kuthuru O, Goodwin EC, Weirick ME, Bolton MJ, Arevalo CP, Ramos A, Jasen C, Giannini HM, DAndrea K, Meyer NJ, Behrens EM, Bassiri H, Hensley SE, Henrickson SE, Teachey DT, Betts MR, Wherry EJ. Vella L, et al. Among authors: kuthuru o. medRxiv. 2020 Sep 27:2020.09.25.20201863. doi: 10.1101/2020.09.25.20201863. Preprint. medRxiv. 2020. PMID: 32995826 Free PMC article. Updated.
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection.
Anderson EM, Goodwin EC, Verma A, Arevalo CP, Bolton MJ, Weirick ME, Gouma S, McAllister CM, Christensen SR, Weaver J, Hicks P, Manzoni TB, Oniyide O, Ramage H, Mathew D, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, D'Andrea K, Kuthuru O, Dougherty J, Pattekar A, Kim J, Han N, Apostolidis SA, Huang AC, Vella LA; UPenn COVID Processing Unit, Wherry EJ, Meyer NJ, Cherry S, Bates P, Rader DJ, Hensley SE. Anderson EM, et al. Among authors: kuthuru o. medRxiv. 2020 Nov 10:2020.11.06.20227215. doi: 10.1101/2020.11.06.20227215. Preprint. medRxiv. 2020. PMID: 33200143 Free PMC article. Updated.
SARS-CoV-2 Seroprevalence Among Parturient Women.
Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Gerber JS, Arevalo CP, Bolton MJ, Weirick ME, Goodwin EC, Anderson EM, Greenplate AR, Kim J, Han N, Pattekar A, Dougherty J, Kuthuru O, Mathew D, Baxter AE, Vella LA, Weaver J, Verma A, Leite R, Morris JS, Rader DJ, Elovitz MA, Wherry EJ, Puopolo KM, Hensley SE. Flannery DD, et al. Among authors: kuthuru o. medRxiv. 2020 Jul 10:2020.07.08.20149179. doi: 10.1101/2020.07.08.20149179. Preprint. medRxiv. 2020. PMID: 32676623 Free PMC article. Updated.
Longitudinal Analysis Reveals Distinct Antibody and Memory B Cell Responses in SARS-CoV2 Naïve and Recovered Individuals Following mRNA Vaccination.
Goel RR, Apostolidis SA, Painter MM, Mathew D, Pattekar A, Kuthuru O, Gouma S, Kuri-Cervantes L, Meng W, Adamski S, Baxter AE, Giles JR, Weirick ME, McAllister CM, Hicks A, Korte S, Dougherty J, Long S, D'Andrea K, Hamilton JT, Prak ETL, Betts MR, Bates P, Hensley SE, Greenplate AR, Wherry EJ. Goel RR, et al. Among authors: kuthuru o. medRxiv. 2021 Mar 6:2021.03.03.21252872. doi: 10.1101/2021.03.03.21252872. Preprint. medRxiv. 2021. PMID: 33688691 Free PMC article. Updated.
Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19.
Apostolidis SA, Sarkar A, Giannini HM, Goel RR, Mathew D, Suzuki A, Baxter AE, Greenplate AR, Alanio C, Abdel-Hakeem M, Oldridge DA, Giles J, Wu JE, Chen Z, Huang YJ, Pattekar A, Manne S, Kuthuru O, Dougherty J, Weiderhold B, Weisman AR, Ittner CAG, Gouma S, Dunbar D, Frank I, Huang AC, Vella LA; UPenn COVID Processing Unit, Reilly JP, Hensley SE, Rauova L, Zhao L, Meyer NJ, Poncz M, Abrams CS, Wherry EJ. Apostolidis SA, et al. Among authors: kuthuru o. bioRxiv. 2021 May 3:2021.05.01.442279. doi: 10.1101/2021.05.01.442279. Preprint. bioRxiv. 2021. PMID: 33972943 Free PMC article.
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