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Year Number of Results
2009 1
2010 1
2013 2
2014 1
2015 4
2016 3
2018 1
2019 1
2021 1
2022 1
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15 results
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Page 1
Optimization of a small-molecule Lipid II binder.
Chauhan J, Kwasny SM, Fletcher S, Opperman TJ, de Leeuw EPH. Chauhan J, et al. Among authors: kwasny sm. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1849-1853. doi: 10.1016/j.bmcl.2019.04.046. Epub 2019 May 17. Bioorg Med Chem Lett. 2019. PMID: 31126852
trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo.
Aron ZD, Mehrani A, Hoffer ED, Connolly KL, Srinivas P, Torhan MC, Alumasa JN, Cabrera M, Hosangadi D, Barbor JS, Cardinale SC, Kwasny SM, Morin LR, Butler MM, Opperman TJ, Bowlin TL, Jerse A, Stagg SM, Dunham CM, Keiler KC. Aron ZD, et al. Among authors: kwasny sm. Nat Commun. 2021 Mar 19;12(1):1799. doi: 10.1038/s41467-021-22012-7. Nat Commun. 2021. PMID: 33741965 Free PMC article.
Structure-activity exploration of a small-molecule Lipid II inhibitor.
Fletcher S, Yu W, Huang J, Kwasny SM, Chauhan J, Opperman TJ, MacKerell AD Jr, de Leeuw E. Fletcher S, et al. Among authors: kwasny sm. Drug Des Devel Ther. 2015 Apr 24;9:2383-94. doi: 10.2147/DDDT.S79504. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 25987836 Free PMC article.
Detour of prenostodione synthesis towards pyrazolones for antibacterial activity.
Rasapalli S, Fan Y, Yu M, Rees C, Harris JT, Golen JA, Jasinski JP, Rheingold AL, Kwasny SM, Opperman TJ. Rasapalli S, et al. Among authors: kwasny sm. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3235-8. doi: 10.1016/j.bmcl.2013.03.123. Epub 2013 Apr 6. Bioorg Med Chem Lett. 2013. PMID: 23611730
Optimized pyridazinone nutrient channel inhibitors are potent and specific antimalarial leads.
Butler MM, Waidyarachchi SL, Shao J, Nguyen ST, Ding X, Cardinale SC, Morin LR, Kwasny SM, Ito M, Gezelle J, Jiminez-Di Az MB, Angulo-Barturen I, Jacobs RT, Burrows JN, Aron ZD, Bowlin TL, Desai SA. Butler MM, et al. Among authors: kwasny sm. Mol Pharmacol. 2022 Jul 7:MOLPHARM-AR-2022-000549. doi: 10.1124/molpharm.122.000549. Online ahead of print. Mol Pharmacol. 2022. PMID: 35798366 Free article.
Towards Development of Small Molecule Lipid II Inhibitors as Novel Antibiotics.
Chauhan J, Cardinale S, Fang L, Huang J, Kwasny SM, Pennington MR, Basi K, diTargiani R, Capacio BR, MacKerell AD Jr, Opperman TJ, Fletcher S, de Leeuw EP. Chauhan J, et al. Among authors: kwasny sm. PLoS One. 2016 Oct 24;11(10):e0164515. doi: 10.1371/journal.pone.0164515. eCollection 2016. PLoS One. 2016. PMID: 27776124 Free PMC article.
15 results