Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1959 1
1964 3
1965 1
1967 1
1968 2
1970 2
1971 1
1973 2
1974 2
1975 4
1976 4
1977 7
1978 5
1979 8
1980 8
1981 9
1982 8
1983 19
1984 22
1985 14
1986 31
1987 30
1988 20
1989 43
1990 38
1991 46
1992 66
1993 40
1994 56
1995 76
1996 74
1997 96
1998 105
1999 115
2000 147
2001 144
2002 172
2003 193
2004 220
2005 296
2006 303
2007 334
2008 356
2009 378
2010 391
2011 405
2012 450
2013 486
2014 539
2015 563
2016 635
2017 630
2018 712
2019 819
2020 933
2021 1061
2022 1166
2023 1181
2024 1348
2025 1506
2026 95

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

14,811 results

Results by year

Filters applied: . Clear all
Page 1
Immunogenic chemotherapy in two mouse colon cancer models.
Taniura T, Iida Y, Kotani H, Ishitobi K, Tajima Y, Harada M. Taniura T, et al. Cancer Sci. 2020 Oct;111(10):3527-3539. doi: 10.1111/cas.14624. Epub 2020 Sep 1. Cancer Sci. 2020. PMID: 32816355 Free PMC article.
In the CT26 model, two injections of 5-FU/L-OHP and CP significantly suppressed the growth of subcutaneously established CT26 tumors compared with either 5-FU/L-OHP or CP, without a significant loss of body weight. ...Analysis of tumor-infiltrating imm …
In the CT26 model, two injections of 5-FU/L-OHP and CP significantly suppressed the growth of subcutaneously established CT26 …
Exosomes secreted by Fusobacterium nucleatum-infected colon cancer cells transmit resistance to oxaliplatin and 5-FU by delivering hsa_circ_0004085.
Hui B, Zhou C, Xu Y, Wang R, Dong Y, Zhou Y, Ding J, Zhang X, Xu J, Gu Y. Hui B, et al. J Nanobiotechnology. 2024 Feb 15;22(1):62. doi: 10.1186/s12951-024-02331-9. J Nanobiotechnology. 2024. PMID: 38360615 Free PMC article.
CONCLUSIONS: Plasma levels of hsa_circ_0004085 are increased in colon cancer patients with intracellular Fn and are associated with a poor response to oxaliplatin/5-FU. Fn infection promoted hsa_circ_0004085 formation by hnRNP L and packaged hsa_circ_0004085 into ex …
CONCLUSIONS: Plasma levels of hsa_circ_0004085 are increased in colon cancer patients with intracellular Fn and are associated with a poor r …
The combination of SHP099 inhibits the malignant biological behavior of L-OHP/5-FU-resistant colorectal cancer cells by regulating energy metabolism reprogramming.
Wang M, Yu K, Fu W, Yang L. Wang M, et al. Biochem Biophys Res Commun. 2024 Oct 8;728:150262. doi: 10.1016/j.bbrc.2024.150262. Epub 2024 Jun 28. Biochem Biophys Res Commun. 2024. PMID: 38959530
RESULTS: Compared with nonresistant strains, L-OHP/5-FU-resistant strains exhibited greater metabolic reprogramming. Functionally, SHP099 can restrain the metabolic reprogramming of L-OHP/5-FU-resistant strains and subsequently restrain the proliferati …
RESULTS: Compared with nonresistant strains, L-OHP/5-FU-resistant strains exhibited greater metabolic reprogramming. Functiona …
Anti-inflammatory effect of L-cysteine (a semi-essential amino acid) on 5-FU-induced oral mucositis in hamsters.
Fonseca KM, Macda RodriguesCosta D, da Silva VF, de Carvalho JL, Oliveira AP, de Melo Sousa FB, Lopes ALF, da Silva Martins C, de Sousa Chaves L, Nicolau LAD, Cerqueira GS, Medeiros JVR. Fonseca KM, et al. Amino Acids. 2021 Sep;53(9):1415-1430. doi: 10.1007/s00726-021-03062-z. Epub 2021 Aug 19. Amino Acids. 2021. PMID: 34410507
In view of these properties, we investigate the effect of L-cys in oral mucositis induced by 5-FU in hamsters. The animals were divided into the following groups: saline 0.9%, mechanical trauma, 5-FU 60-40 mg/kg, L-cys 10/40 mg and NaHS 27 g/kg. 5-F …
In view of these properties, we investigate the effect of L-cys in oral mucositis induced by 5-FU in hamsters. The animals wer …
5-FU preferably induces apoptosis in BRAF V600E colorectal cancer cells via downregulation of Bcl-x(L).
Shi T, Gao M, He M, Yue F, Zhao Y, Sun M, He K, Chen L. Shi T, et al. Mol Cell Biochem. 2019 Nov;461(1-2):151-158. doi: 10.1007/s11010-019-03598-5. Epub 2019 Jul 27. Mol Cell Biochem. 2019. PMID: 31352611
Our results revealed 5-FU preferably induces marked apoptosis in BRAF-mutant colorectal cancer cells, through attenuating expression of Bcl-x(L) and activation caspase-3/9 pathway, eventually conferring the anti-tumor efficacy of 5-FU in vitro and in vivo. Me …
Our results revealed 5-FU preferably induces marked apoptosis in BRAF-mutant colorectal cancer cells, through attenuating expression …
L-arginine combination with 5-fluorouracil inhibit hepatocellular carcinoma cells through suppressing iNOS/NO/AKT-mediated glycolysis.
Hu Y, Xing Y, Fan G, Xie H, Zhao Q, Liu L. Hu Y, et al. Front Pharmacol. 2024 May 22;15:1391636. doi: 10.3389/fphar.2024.1391636. eCollection 2024. Front Pharmacol. 2024. PMID: 38841361 Free PMC article.
Meanwhile, L-arginine increased 5-FU inhibitory effect on HepG2 and SMMC7721 cells by increasing NO production. Co-treatment with L-arginine and 5-FU resulted in a significant decrease in both G6PDH and LDH enzymatic activities, as well as reduced leve …
Meanwhile, L-arginine increased 5-FU inhibitory effect on HepG2 and SMMC7721 cells by increasing NO production. Co-treatment w …
Effects of L-Arginine Supplementation on Leukogram, Inflammatory Bowel Infiltrates and Immunoglobulins with 5-FU Use in Rats.
Balmant BD, Araújo EON, Yabuki D, Novais AB, Genaro SC, Laposy CB, Goiozo PFI, Chacur MGM, Giuffrida R, Reis LSLS. Balmant BD, et al. Nutr Cancer. 2018 Feb-Mar;70(2):249-256. doi: 10.1080/01635581.2018.1424346. Epub 2018 Jan 18. Nutr Cancer. 2018. PMID: 29345500
Thirty-two Wistar rats were randomly distributed into 4 groups (8 rats/group): an untreated control group, and test groups receiving one dose of 5-FU (G(5-FU) group), one dose of 5-FU and 295 mg L-arginine/day (G(Arg295) group) or one dose of 5-FU …
Thirty-two Wistar rats were randomly distributed into 4 groups (8 rats/group): an untreated control group, and test groups receiving one dos …
Selenium-Mediated (-)-Epigallocatechin-3-Gallate Dynamics via Flavanone-3-Hydroxylase Regulation of Flavonoid Biosynthesis in Fu Tea (Camellia sinensis (L.) O. Kuntze).
Guo A, Jia W, Wang X. Guo A, et al. J Agric Food Chem. 2024 Jun 5. doi: 10.1021/acs.jafc.4c02987. Online ahead of print. J Agric Food Chem. 2024. PMID: 38840526
Combining Word2vec and HNSW utilizing UHPLC-Q-Orbitrap HRMS-MS/MS to implement rapid matching annotation of the structural information on metabolites in Fu tea, we found that selenium-mediated changes in catechins in Fu tea were mainly associated with flavonoid bios …
Combining Word2vec and HNSW utilizing UHPLC-Q-Orbitrap HRMS-MS/MS to implement rapid matching annotation of the structural information on me …
L-arginine pretreatment reduces intestinal mucositis as induced by 5-FU in mice.
Leocádio PC, Antunes MM, Teixeira LG, Leonel AJ, Alvarez-Leite JI, Machado DC, Generoso SV, Cardoso VN, Correia MI. Leocádio PC, et al. Nutr Cancer. 2015;67(3):486-93. doi: 10.1080/01635581.2015.1004730. Epub 2015 Mar 24. Nutr Cancer. 2015. PMID: 25803482
The aim of this study was to evaluate the effect of pretreating with 2% L-arginine supplementation in water on mucositis as induced by 5-fluorouracil (5-FU; a single dose of 200 mg/kg body weight) in Swiss male mice. ...Intestinal length improvement was observed, in …
The aim of this study was to evaluate the effect of pretreating with 2% L-arginine supplementation in water on mucositis as induced b …
l-arginine minimizes immunosuppression and prothrombin time and enhances the genotoxicity of 5-fluorouracil in rats.
de Andrade Bernal Fagiani M, Fluminhan A, de Azevedo Mello F, Yabuki D, Gonçalves GV, Tsujigushi LK, Pereira LG, da Silva KA, da Silva SBB, Santarem CL, Giozo PFI, de Souza Reis LSL. de Andrade Bernal Fagiani M, et al. Nutrition. 2019 Oct;66:94-100. doi: 10.1016/j.nut.2019.04.012. Epub 2019 May 23. Nutrition. 2019. PMID: 31252338
METHODS: Thirty-two Wistar rats were fed commercial feed and water ad libitum and grouped into four (eight rats per group): The control group was given a 0.9% physiologic solution to simulate the application of 5-FU in the other groups; the G(5-FU) group was given a …
METHODS: Thirty-two Wistar rats were fed commercial feed and water ad libitum and grouped into four (eight rats per group): The control grou …
14,811 results
You have reached the last available page of results. Please see the User Guide for more information.