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2001 1
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13 results

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Page 1
Whole-genome sequencing reveals host factors underlying critical COVID-19.
Kousathanas A, Pairo-Castineira E, Rawlik K, Stuckey A, Odhams CA, Walker S, Russell CD, Malinauskas T, Wu Y, Millar J, Shen X, Elliott KS, Griffiths F, Oosthuyzen W, Morrice K, Keating S, Wang B, Rhodes D, Klaric L, Zechner M, Parkinson N, Siddiq A, Goddard P, Donovan S, Maslove D, Nichol A, Semple MG, Zainy T, Maleady-Crowe F, Todd L, Salehi S, Knight J, Elgar G, Chan G, Arumugam P, Patch C, Rendon A, Bentley D, Kingsley C, Kosmicki JA, Horowitz JE, Baras A, Abecasis GR, Ferreira MAR, Justice A, Mirshahi T, Oetjens M, Rader DJ, Ritchie MD, Verma A, Fowler TA, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Elliott P, Walsh T, Tenesa A; GenOMICC investigators; 23andMe investigators; COVID-19 Human Genetics Initiative; Fawkes A, Murphy L, Rowan K, Ponting CP, Vitart V, Wilson JF, Yang J, Bretherick AD, Scott RH, Hendry SC, Moutsianas L, Law A, Caulfield MJ, Baillie JK. Kousathanas A, et al. Nature. 2022 Jul;607(7917):97-103. doi: 10.1038/s41586-022-04576-6. Epub 2022 Mar 7. Nature. 2022. PMID: 35255492 Free PMC article.
A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
NIHR Global Health Research Unit on Global Surgery; STARSurg Collaborative. NIHR Global Health Research Unit on Global Surgery, et al. Lancet Digit Health. 2024 Jul;6(7):e507-e519. doi: 10.1016/S2589-7500(24)00065-7. Lancet Digit Health. 2024. PMID: 38906616 Free PMC article.
Plasma neurofilament light chain concentration is increased in anorexia nervosa.
Nilsson IAK, Millischer V, Karrenbauer VD, Juréus A, Salehi AM, Norring C, von Hausswolff-Juhlin Y, Schalling M, Blennow K, Bulik CM, Zetterberg H, Landén M. Nilsson IAK, et al. Transl Psychiatry. 2019 Aug 1;9(1):180. doi: 10.1038/s41398-019-0518-2. Transl Psychiatry. 2019. PMID: 31371701 Free PMC article.
GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis.
De Marinis YZ, Salehi A, Ward CE, Zhang Q, Abdulkader F, Bengtsson M, Braha O, Braun M, Ramracheya R, Amisten S, Habib AM, Moritoh Y, Zhang E, Reimann F, Rosengren A, Shibasaki T, Gribble F, Renström E, Seino S, Eliasson L, Rorsman P. De Marinis YZ, et al. Cell Metab. 2010 Jun 9;11(6):543-553. doi: 10.1016/j.cmet.2010.04.007. Cell Metab. 2010. PMID: 20519125 Free PMC article.
Adrenaline stimulates alpha cell electrical activity, increases [Ca(2+)](i), enhances L-type Ca(2+) channel activity, and accelerates exocytosis. The stimulatory effect is partially PKA independent and reduced in Epac2-deficient islets. We propose that GLP-1 inhibits gluca …
Adrenaline stimulates alpha cell electrical activity, increases [Ca(2+)](i), enhances L-type Ca(2+) channel activity, and accelerates …
Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells.
Olofsson CS, Salehi A, Holm C, Rorsman P. Olofsson CS, et al. J Physiol. 2004 Jun 15;557(Pt 3):935-48. doi: 10.1113/jphysiol.2004.066258. Epub 2004 Apr 16. J Physiol. 2004. PMID: 15090611 Free PMC article.
Whole-cell peak Ca(2+) currents rose by approximately 25% following addition of 0.5 mm palmitate, an effect that was abolished in the presence of 10 microm isradipine indicating that the free fatty acid specifically acts on L-type Ca(2+) channels. The actions of palmitate …
Whole-cell peak Ca(2+) currents rose by approximately 25% following addition of 0.5 mm palmitate, an effect that was abolished in the presen …
Antitrypanosomal isothiocyanate and thiocarbamate glycosides from Moringa peregrina.
Ayyari M, Salehi P, Ebrahimi SN, Zimmermann S, Portmann L, Krauth-Siegel RL, Kaiser M, Brun R, Rezadoost H, Rezazadeh S, Hamburger M. Ayyari M, et al. Planta Med. 2014 Jan;80(1):86-9. doi: 10.1055/s-0033-1351102. Epub 2013 Dec 5. Planta Med. 2014. PMID: 24310210
O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(alpha-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(alpha-L-rhamnosyloxy) benzyl isothiocyanate (4) have been isolated from the aerial parts of Moringa peregrina. ...Because of its high in vitro activity and …
O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(alpha-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(alpha-L-rhamnosy …
Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice.
Schulla V, Renström E, Feil R, Feil S, Franklin I, Gjinovci A, Jing XJ, Laux D, Lundquist I, Magnuson MA, Obermüller S, Olofsson CS, Salehi A, Wendt A, Klugbauer N, Wollheim CB, Rorsman P, Hofmann F. Schulla V, et al. EMBO J. 2003 Aug 1;22(15):3844-54. doi: 10.1093/emboj/cdg389. EMBO J. 2003. PMID: 12881419 Free PMC article.
Mouse beta cells express several types of Ca(2+) channel (L-, R- and possibly P/Q-type). beta cell-selective ablation of the gene encoding the L-type Ca(2+) channel subtype Ca(v)1.2 (betaCa(v)1.2(-/-) mouse) decreased the whole-cell Ca(2+) current by only approximat …
Mouse beta cells express several types of Ca(2+) channel (L-, R- and possibly P/Q-type). beta cell-selective ablation of the gene enc …
Mitigating effects of agmatine on myocardial infarction in rats subjected to isoproterenol.
Elieh-Ali-Komi D, Yarmohammadi F, Nezamabadi M, Khirehgesh MR, Kiani M, Rashidi K, Mohammadi-Noori E, Salehi N, Dehpour AR, Kiani A. Elieh-Ali-Komi D, et al. Naunyn Schmiedebergs Arch Pharmacol. 2025 Apr;398(4):4279-4290. doi: 10.1007/s00210-024-03545-2. Epub 2024 Oct 24. Naunyn Schmiedebergs Arch Pharmacol. 2025. PMID: 39446151

The administration of agmatine to ISO-receiving group could mitigate several parameters when compared to ISO-receiving group including increasing papillary muscle contraction (0.83 vs 0.71 N/M(2) respectively, P < 0.01), decreasing LDH levels (660 ng/ml vs 1080 ng/ml, respecti

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The administration of agmatine to ISO-receiving group could mitigate several parameters when compared to ISO-receiving group including incre …
13 results