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A mechanistic, model-based approach to safety assessment in clinical development.
Lippert J, Brosch M, von Kampen O, Meyer M, Siegmund HU, Schafmayer C, Becker T, Laffert B, Görlitz L, Schreiber S, Neuvonen PJ, Niemi M, Hampe J, Kuepfer L. Lippert J, et al. Among authors: laffert b. CPT Pharmacometrics Syst Pharmacol. 2012 Nov 7;1(11):e13. doi: 10.1038/psp.2012.14. CPT Pharmacometrics Syst Pharmacol. 2012. PMID: 23835795 Free PMC article.