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Page 1
Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein.
Armenta DA, Laqtom NN, Alchemy G, Dong W, Morrow D, Poltorack CD, Nathanson DA, Abu-Remalieh M, Dixon SJ. Armenta DA, et al. Among authors: laqtom nn. Cell Chem Biol. 2022 Nov 17;29(11):1588-1600.e7. doi: 10.1016/j.chembiol.2022.10.006. Epub 2022 Oct 27. Cell Chem Biol. 2022. PMID: 36306785 Free PMC article.
NUFIP1 is a ribosome receptor for starvation-induced ribophagy.
Wyant GA, Abu-Remaileh M, Frenkel EM, Laqtom NN, Dharamdasani V, Lewis CA, Chan SH, Heinze I, Ori A, Sabatini DM. Wyant GA, et al. Among authors: laqtom nn. Science. 2018 May 18;360(6390):751-758. doi: 10.1126/science.aar2663. Epub 2018 Apr 26. Science. 2018. PMID: 29700228 Free PMC article.
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes.
Laqtom NN, Dong W, Medoh UN, Cangelosi AL, Dharamdasani V, Chan SH, Kunchok T, Lewis CA, Heinze I, Tang R, Grimm C, Dang Do AN, Porter FD, Ori A, Sabatini DM, Abu-Remaileh M. Laqtom NN, et al. Nature. 2022 Sep;609(7929):1005-1011. doi: 10.1038/s41586-022-05221-y. Epub 2022 Sep 21. Nature. 2022. PMID: 36131016 Free PMC article.
Structural basis for the docking of mTORC1 on the lysosomal surface.
Rogala KB, Gu X, Kedir JF, Abu-Remaileh M, Bianchi LF, Bottino AMS, Dueholm R, Niehaus A, Overwijn D, Fils AP, Zhou SX, Leary D, Laqtom NN, Brignole EJ, Sabatini DM. Rogala KB, et al. Among authors: laqtom nn. Science. 2019 Oct 25;366(6464):468-475. doi: 10.1126/science.aay0166. Epub 2019 Oct 10. Science. 2019. PMID: 31601708 Free PMC article.
Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration.
Vest RT, Chou CC, Zhang H, Haney MS, Li L, Laqtom NN, Chang B, Shuken S, Nguyen A, Yerra L, Yang AC, Green C, Tanga M, Abu-Remaileh M, Bassik MC, Frydman J, Luo J, Wyss-Coray T. Vest RT, et al. Among authors: laqtom nn. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2121609119. doi: 10.1073/pnas.2121609119. Epub 2022 Mar 8. Proc Natl Acad Sci U S A. 2022. PMID: 35259016 Free PMC article.
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals.
Pedram K, Laqtom NN, Shon DJ, Di Spiezio A, Riley NM, Saftig P, Abu-Remaileh M, Bertozzi CR. Pedram K, et al. Among authors: laqtom nn. Proc Natl Acad Sci U S A. 2022 Sep 27;119(39):e2117105119. doi: 10.1073/pnas.2117105119. Epub 2022 Sep 19. Proc Natl Acad Sci U S A. 2022. PMID: 36122205 Free PMC article.
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes.
Jungnickel KEJ, Guelle O, Iguchi M, Dong W, Kotov V, Gabriel F, Debacker C, Dairou J, McCort-Tranchepain I, Laqtom NN, Chan SH, Ejima A, Sato K, Massa López D, Saftig P, Mehdipour AR, Abu-Remaileh M, Gasnier B, Löw C, Damme M. Jungnickel KEJ, et al. Among authors: laqtom nn. Nat Cell Biol. 2024 Jun 5. doi: 10.1038/s41556-024-01436-5. Online ahead of print. Nat Cell Biol. 2024. PMID: 38839979
12 results