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From affinity selection to kinetic selection in Germinal Centre modelling.
Lashgari D, Merino Tejero E, Meyer-Hermann M, Claireaux MAF, van Gils MJ, Hoefsloot HCJ, van Kampen AHC. Lashgari D, et al. PLoS Comput Biol. 2022 Jun 3;18(6):e1010168. doi: 10.1371/journal.pcbi.1010168. eCollection 2022 Jun. PLoS Comput Biol. 2022. PMID: 35658003 Free PMC article.
Understanding repertoire sequencing data through a multiscale computational model of the germinal center.
García-Valiente R, Merino Tejero E, Stratigopoulou M, Balashova D, Jongejan A, Lashgari D, Pélissier A, Caniels TG, Claireaux MAF, Musters A, van Gils MJ, Rodríguez Martínez M, de Vries N, Meyer-Hermann M, Guikema JEJ, Hoefsloot H, van Kampen AHC. García-Valiente R, et al. Among authors: lashgari d. NPJ Syst Biol Appl. 2023 Mar 16;9(1):8. doi: 10.1038/s41540-023-00271-y. NPJ Syst Biol Appl. 2023. PMID: 36927990 Free PMC article.
Coupled Antigen and BLIMP1 Asymmetric Division With a Large Segregation Between Daughter Cells Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells and a DZ-to-LZ Ratio in the Germinal Center.
Merino Tejero E, Lashgari D, García-Valiente R, He J, Robert PA, Meyer-Hermann M, Guikema JEJ, Hoefsloot H, van Kampen AHC. Merino Tejero E, et al. Among authors: lashgari d. Front Immunol. 2021 Aug 17;12:716240. doi: 10.3389/fimmu.2021.716240. eCollection 2021. Front Immunol. 2021. PMID: 34484219 Free PMC article.
Multiscale Modeling of Germinal Center Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells Differentiation as Regulated by Antigen Affinity-Based Tfh Cell Help.
Merino Tejero E, Lashgari D, García-Valiente R, Gao X, Crauste F, Robert PA, Meyer-Hermann M, Martínez MR, van Ham SM, Guikema JEJ, Hoefsloot H, van Kampen AHC. Merino Tejero E, et al. Among authors: lashgari d. Front Immunol. 2021 Feb 5;11:620716. doi: 10.3389/fimmu.2020.620716. eCollection 2020. Front Immunol. 2021. PMID: 33613551 Free PMC article.