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Year Number of Results
1998 1
2001 1
2003 1
2013 1
2014 4
2016 1
2019 1
2020 2
2021 0
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12 results
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IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A. Harnoss JM, et al. Among authors: le thomas a. Cancer Res. 2020 Jun 1;80(11):2368-2379. doi: 10.1158/0008-5472.CAN-19-3108. Epub 2020 Apr 7. Cancer Res. 2020. PMID: 32265225 Free PMC article.
Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen YA, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun MG, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A. Harnoss JM, et al. Among authors: le thomas a. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16420-16429. doi: 10.1073/pnas.1906999116. Epub 2019 Aug 1. Proc Natl Acad Sci U S A. 2019. PMID: 31371506 Free PMC article.
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands.
Ferri E, Le Thomas A, Wallweber HA, Day ES, Walters BT, Kaufman SE, Braun MG, Clark KR, Beresini MH, Mortara K, Chen YA, Canter B, Phung W, Liu PS, Lammens A, Ashkenazi A, Rudolph J, Wang W. Ferri E, et al. Among authors: le thomas a. Nat Commun. 2020 Dec 14;11(1):6387. doi: 10.1038/s41467-020-19974-5. Nat Commun. 2020. PMID: 33318494 Free PMC article.
A framework for piRNA cluster manipulation.
Olovnikov I, Le Thomas A, Aravin AA. Olovnikov I, et al. Among authors: le thomas a. Methods Mol Biol. 2014;1093:47-58. doi: 10.1007/978-1-62703-694-8_5. Methods Mol Biol. 2014. PMID: 24178556
Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors.
Chen YA, Stuwe E, Luo Y, Ninova M, Le Thomas A, Rozhavskaya E, Li S, Vempati S, Laver JD, Patel DJ, Smibert CA, Lipshitz HD, Toth KF, Aravin AA. Chen YA, et al. Among authors: le thomas a. Mol Cell. 2016 Jul 7;63(1):97-109. doi: 10.1016/j.molcel.2016.05.010. Epub 2016 Jun 9. Mol Cell. 2016. PMID: 27292797 Free PMC article.
[Polygamy in Atriplex halimus L. (Chenopodiaceae)].
Talamali A, Dutuit P, Le Thomas A, Gorenflot R. Talamali A, et al. Among authors: le thomas a. C R Acad Sci III. 2001 Feb;324(2):107-13. doi: 10.1016/s0764-4469(00)01273-7. C R Acad Sci III. 2001. PMID: 11280041 French.
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