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COVID-19-associated coagulopathy and antithrombotic agents-lessons after 1 year.

Leentjens J, van Haaps TF, Wessels PF, Schutgens REG, Middeldorp S. Leentjens J, et al. Lancet Haematol. 2021 Jul;8(7):e524-e533. doi: 10.1016/S2352-3026(21)00105-8. Epub 2021 Apr 27. Lancet Haematol. 2021. PMID: 33930350 Free PMC article. Review.

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Initial anticoagulation in patients with pulmonary embolism: thrombolysis, unfractionated heparin, LMWH, fondaparinux, or DOACs?

Leentjens J, Peters M, Esselink AC, Smulders Y, Kramers C. Leentjens J, et al. Br J Clin Pharmacol. 2017 Nov;83(11):2356-2366. doi: 10.1111/bcp.13340. Epub 2017 Jul 9. Br J Clin Pharmacol. 2017. PMID: 28593681 Free PMC article. Review.

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Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.

Cheng SC, Scicluna BP, Arts RJ, Gresnigt MS, Lachmandas E, Giamarellos-Bourboulis EJ, Kox M, Manjeri GR, Wagenaars JA, Cremer OL, Leentjens J, van der Meer AJ, van de Veerdonk FL, Bonten MJ, Schultz MJ, Willems PH, Pickkers P, Joosten LA, van der Poll T, Netea MG. Cheng SC, et al. Among authors: leentjens j. Nat Immunol. 2016 Apr;17(4):406-13. doi: 10.1038/ni.3398. Epub 2016 Mar 7. Nat Immunol. 2016. PMID: 26950237

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[Checkpoint inhibitor induced diabetes mellitus].

Leentjens J, Olde Bekkink M, Koot R, Herbschleb KH, de Galan BE. Leentjens J, et al. Ned Tijdschr Geneeskd. 2019 Aug 19;163:D3726. Ned Tijdschr Geneeskd. 2019. PMID: 31433147 Dutch.

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Trained Innate Immunity as a Novel Mechanism Linking Infection and the Development of Atherosclerosis.

Leentjens J, Bekkering S, Joosten LAB, Netea MG, Burgner DP, Riksen NP. Leentjens J, et al. Circ Res. 2018 Mar 2;122(5):664-669. doi: 10.1161/CIRCRESAHA.117.312465. Epub 2018 Jan 24. Circ Res. 2018. PMID: 29367213 Review.

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Immunotherapy for the adjunctive treatment of sepsis: from immunosuppression to immunostimulation. Time for a paradigm change?

Leentjens J, Kox M, van der Hoeven JG, Netea MG, Pickkers P. Leentjens J, et al. Am J Respir Crit Care Med. 2013 Jun 15;187(12):1287-93. doi: 10.1164/rccm.201301-0036CP. Am J Respir Crit Care Med. 2013. PMID: 23590272 Review.

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Incidence of thrombotic complications and overall survival in hospitalized patients with COVID-19 in the second and first wave.

Dutch COVID & Thrombosis Coalition, Kaptein FHJ, Stals MAM, Grootenboers M, Braken SJE, Burggraaf JLI, van Bussel BCT, Cannegieter SC, Ten Cate H, Endeman H, Gommers DAMPJ, van Guldener C, de Jonge E, Juffermans NP, Kant KM, Kevenaar ME, Koster S, Kroft LJM, Kruip MJHA, Leentjens J, Marechal C, Soei YL, Tjepkema L, Visser C, Klok FA, Huisman MV. Dutch COVID & Thrombosis Coalition, et al. Among authors: leentjens j. Thromb Res. 2021 Mar;199:143-148. doi: 10.1016/j.thromres.2020.12.019. Epub 2020 Dec 30. Thromb Res. 2021. PMID: 33535120 Free PMC article.

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Prior use of therapeutic anticoagulation does not protect against COVID-19 related clinical outcomes in hospitalized patients: A propensity score-matched cohort study.

Spiegelenberg JP, van Gelder MMHJ, Maas ML, Hovens MMC, Esselink A, Dofferhoff ASM, Janssen R, van de Maat J, Janssen N, Blaauw M, Hassing RJ, van Apeldoorn M, Kerckhoffs A, Veerman K, Hoogerwerf J, Kramers C, Leentjens J. Spiegelenberg JP, et al. Among authors: leentjens j. Br J Clin Pharmacol. 2021 Dec;87(12):4839-4847. doi: 10.1111/bcp.14877. Epub 2021 May 7. Br J Clin Pharmacol. 2021. PMID: 33899226 Free PMC article.

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[Immunomodulation for sepsis: a change of tack?].

Leentjens J, Kox M, Pickkers P. Leentjens J, et al. Ned Tijdschr Geneeskd. 2014;158:A6859. Ned Tijdschr Geneeskd. 2014. PMID: 24518844 Dutch.

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Multicentric experience with interferon gamma therapy in sepsis induced immunosuppression. A case series.

Payen D, Faivre V, Miatello J, Leentjens J, Brumpt C, Tissières P, Dupuis C, Pickkers P, Lukaszewicz AC. Payen D, et al. Among authors: leentjens j. BMC Infect Dis. 2019 Nov 5;19(1):931. doi: 10.1186/s12879-019-4526-x. BMC Infect Dis. 2019. PMID: 31690258 Free PMC article.

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