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Page 1
The Cancer SENESCopedia: A delineation of cancer cell senescence.
Jochems F, Thijssen B, De Conti G, Jansen R, Pogacar Z, Groot K, Wang L, Schepers A, Wang C, Jin H, Beijersbergen RL, Leite de Oliveira R, Wessels LFA, Bernards R. Jochems F, et al. Among authors: leite de oliveira r. Cell Rep. 2021 Jul 27;36(4):109441. doi: 10.1016/j.celrep.2021.109441. Cell Rep. 2021. PMID: 34320349 Free PMC article.
An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.
Wang L, Leite de Oliveira R, Huijberts S, Bosdriesz E, Pencheva N, Brunen D, Bosma A, Song JY, Zevenhoven J, Los-de Vries GT, Horlings H, Nuijen B, Beijnen JH, Schellens JHM, Bernards R. Wang L, et al. Among authors: leite de oliveira r. Cell. 2018 May 31;173(6):1413-1425.e14. doi: 10.1016/j.cell.2018.04.012. Epub 2018 May 10. Cell. 2018. PMID: 29754815 Free article.
With great power comes great vulnerability.
Leite de Oliveira R, Wang L, Bernards R. Leite de Oliveira R, et al. Mol Cell Oncol. 2018 Oct 9;5(6):e1509488. doi: 10.1080/23723556.2018.1509488. eCollection 2018. Mol Cell Oncol. 2018. PMID: 30525088 Free PMC article.
Anti-cancer therapy: senescence is the new black.
Leite de Oliveira R, Bernards R. Leite de Oliveira R, et al. EMBO J. 2018 May 15;37(10):e99386. doi: 10.15252/embj.201899386. Epub 2018 Apr 18. EMBO J. 2018. PMID: 29669859 Free PMC article.
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.
Pogacar Z, Johnson JL, Krenning L, De Conti G, Jochems F, Lieftink C, Velds A, Wardak L, Groot K, Schepers A, Wang L, Song JY, van de Ven M, van Tellingen O, Medema RH, Beijersbergen RL, Bernards R, Leite de Oliveira R. Pogacar Z, et al. Among authors: leite de oliveira r. PLoS One. 2022 Sep 6;17(9):e0273182. doi: 10.1371/journal.pone.0273182. eCollection 2022. PLoS One. 2022. PMID: 36067171 Free PMC article.
Genetic and compound screens uncover factors modulating cancer cell response to indisulam.
Pogacar Z, Groot K, Jochems F, Dos Santos Dias M, Mulero-Sánchez A, Morris B, Roosen M, Wardak L, De Conti G, Velds A, Lieftink C, Thijssen B, Beijersbergen RL, Bernards R, Leite de Oliveira R. Pogacar Z, et al. Among authors: leite de oliveira r. Life Sci Alliance. 2022 May 9;5(9):e202101348. doi: 10.26508/lsa.202101348. Print 2022 Sep. Life Sci Alliance. 2022. PMID: 35534224 Free PMC article.
Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.
Schepers A, Jochems F, Lieftink C, Wang L, Pogacar Z, Leite de Oliveira R, De Conti G, Beijersbergen RL, Bernards R. Schepers A, et al. Among authors: leite de oliveira r. Mol Cancer Res. 2021 Oct;19(10):1613-1621. doi: 10.1158/1541-7786.MCR-21-0146. Epub 2021 Jun 22. Mol Cancer Res. 2021. PMID: 34158393 Free PMC article.
14 results