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P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate.
Zhang S, Zhang L, Greule A, Tailhades J, Marschall E, Prasongpholchai P, Leng DJ, Zhang J, Zhu J, Kaczmarski JA, Schittenhelm RB, Einsle O, Jackson CJ, Alberti F, Bechthold A, Zhang Y, Tosin M, Si T, Cryle MJ. Zhang S, et al. Among authors: leng dj. Acta Pharm Sin B. 2023 Aug;13(8):3561-3574. doi: 10.1016/j.apsb.2023.03.021. Epub 2023 Mar 29. Acta Pharm Sin B. 2023. PMID: 37655329 Free PMC article.
Novel chemical probes for the investigation of nonribosomal peptide assembly.
Ho YTC, Leng DJ, Ghiringhelli F, Wilkening I, Bushell DP, Kostner O, Riva E, Havemann J, Passarella D, Tosin M. Ho YTC, et al. Among authors: leng dj. Chem Commun (Camb). 2017 Jun 27;53(52):7088-7091. doi: 10.1039/c7cc02427d. Chem Commun (Camb). 2017. PMID: 28627528 Free article.